Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Antibodies/chemistry"'
Publikováno v:
Methods in Molecular Biology ISBN: 9781071620748
Peste des petits ruminants virus (PPRV) causes a highly devastating disease, peste des petits ruminants (PPR) of sheep and goats, that threatens food security, small ruminant production, and the conservation of wild small ruminants in many developing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34dda803f47bac8f0e54ab2bcf3e4036
https://biblio.vub.ac.be/vubir/(b574ee24-d3de-44cc-a12d-9ef036c11a19).html
https://biblio.vub.ac.be/vubir/(b574ee24-d3de-44cc-a12d-9ef036c11a19).html
Autor:
Thinzar M. Lwin, Michael A. Turner, Hiroto Nishino, Siamak Amirfakhri, Sophie Hernot, Robert M. Hoffman, Michael Bouvet
Publikováno v:
Biomolecules, vol 12, iss 5
Biomolecules; Volume 12; Issue 5; Pages: 711
Biomolecules; Volume 12; Issue 5; Pages: 711
Tumor-specific targeting with fluorescent probes can enhance contrast for identification of cancer during surgical resection and visualize otherwise invisible tumor margins. Nanobodies are the smallest naturally-occurring antigen-binding molecules wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef471ac055ec50b37dd11e53a93a8f67
https://escholarship.org/uc/item/8xx7m201
https://escholarship.org/uc/item/8xx7m201
Autor:
Märcher, Anders, Gothelf, Kurt V.
Publikováno v:
Methods in Molecular Biology ISBN: 9781071620748
Märcher, A & Gothelf, K V 2022, Affinity-Guided Site-Selective Labeling of Nanobodies with Aldehyde Handles . in G Hussack & K A Henry (eds), Single-Domain Antibodies : Methods in Molecular Biology . vol. 2446, Humana Press, New York, Methods in Molecular Biology, vol. 2446, pp. 345-356 . https://doi.org/10.1007/978-1-0716-2075-5_17
Märcher, A & Gothelf, K V 2022, Affinity-Guided Site-Selective Labeling of Nanobodies with Aldehyde Handles . in G Hussack & K A Henry (eds), Single-Domain Antibodies : Methods in Molecular Biology . vol. 2446, Humana Press, New York, Methods in Molecular Biology, vol. 2446, pp. 345-356 . https://doi.org/10.1007/978-1-0716-2075-5_17
Antigen-binding proteins such as nanobodies are extensively used in biomedicine, diagnostics, and as tools for molecular biology. Often such applications require modification of the nanobodies with fluorophores or drugs. Here, we describe a robust me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beefc45b57107a2b11b598c873936877
https://doi.org/10.1007/978-1-0716-2075-5_17
https://doi.org/10.1007/978-1-0716-2075-5_17
Publikováno v:
Methods in Molecular Biology ISBN: 9781071620748
Near-infrared fluorescence molecular imaging has become an established preclinical technique to investigate molecular processes in vivo and to study novel therapies. Furthermore, fluorescence molecular imaging is gaining significant interest from cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c43d4b9089ff59fb613575eeb7d2cd
https://doi.org/10.1007/978-1-0716-2075-5_20
https://doi.org/10.1007/978-1-0716-2075-5_20
Autor:
Sha Li, Sandra Bouchy, Carine Michiels, Bernard Gallez, Olivier Feron, Stéphane Lucas, Philippe Martinive, Anne-Catherine Heuskin, Riccardo Marega, Ornella Fichera, Sébastien Penninckx
Publikováno v:
Nanomedicine (London, England), Vol. 14, p. 317-333 (2019)
AIM: This study aimed at developing antibody-functionalized gold nanoparticles (AuNPs) to selectively target cancer cells and probing their potential radiosensitizing effects under proton irradiation.MATERIALS & METHODS: AuNPs were conjugated with ce
Autor:
D. Proverbio, T. Kralj, Madelon M. Maurice, Piet Gros, Sarah Stryeck, M. Goldflam, C. Ullman, G. Hermans, T. Aastrup, R.C. van Scherpenzeel, T.Z. Bass, Ingrid Jordens, Nicola Fenderico
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications, 10(1), 365. Nature Publishing Group
'Nature Communications ', vol: 10, pages: 365-1-365-13 (2019)
Nature Communications
Nature Communications, 10(1), 365. Nature Publishing Group
'Nature Communications ', vol: 10, pages: 365-1-365-13 (2019)
Wnt-induced β-catenin-mediated transcription is a driving force for stem cell self-renewal during adult tissue homeostasis. Enhanced Wnt receptor expression due to mutational inactivation of the ubiquitin ligases RNF43/ZNRF3 recently emerged as a le
Autor:
Irina Smirnova, H. Ronald Kaback, Xiaoxu Jiang, Els Pardon, Robert M. Stroud, Jan Steyaert, Vladimir N. Kasho, Janet Finer-Moore, Hemant Kumar
Publikováno v:
Proceedings of the National Academy of Sciences. 115:8769-8774
The lactose permease of Escherichia coli (LacY), a dynamic polytopic membrane transport protein, catalyzes galactoside/H(+) symport and operates by an alternating access mechanism that exhibits multiple conformations, the distribution of which is alt
Autor:
Jan Steyaert, Yuan Cai, Ikuo Masuho, Sahil Gulati, Christopher P. Ford, Krzysztof Palczewski, Kirill A. Martemyanov, Tivadar Orban, Els Pardon, Philip D. Kiser, Hui Jin, Phoebe L. Stewart
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications
Nature Communications
G protein-coupled receptors (GPCRs) activate heterotrimeric G proteins by mediating a GDP to GTP exchange in the Gα subunit. This leads to dissociation of the heterotrimer into Gα-GTP and Gβγ dimer. The Gα-GTP and Gβγ dimer each regulate a var
Publikováno v:
Analytical Chemistry, 89(6), 3402-3410. American Chemical Society
Analytical Chemistry
Analytical Chemistry
Because of their high surface-to-volume ratio and adaptable surface functionalization, particles are widely used in bioanalytical methods to capture molecular targets. In this article, a comprehensive study is reported of the effectiveness of protein
Publikováno v:
Annual Review of Pharmacology and Toxicology. 57:19-37
Ligand-induced activation of G protein-coupled receptors (GPCRs) is a key mechanism permitting communication between cells and organs. Enormous progress has recently elucidated the structural and dynamic features of GPCR transmembrane signaling. Nano