Výsledky vyhledávání - "Antibodies, Monoclonal/immunology"

Manifold Roles of CCR7 and Its Ligands in the Induction and Maintenance of Bronchus-Associated Lymphoid Tissue

Autor: Sanjiv A. Luther, Gerd Sutter, Reinhold Förster, Anja Bubke, Marc Permanyer, Stefanie Willenzon, Berislav Bošnjak, Henrike Fleige, Jasmin Ristenpart

Publikováno v: Cell reports, vol. 23, no. 3, pp. 783-795
Cell Reports, Vol 23, Iss 3, Pp 783-795 (2018)

Summary: The processes underlying the development and maintenance of tertiary lymphoid organs are incompletely understood. Using a Ccr7 knockout/knockin approach, we show that spontaneous bronchus-associated lymphoid tissue (BALT) formation can be ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c34892c25d581f23ba5b5724047ddf4
https://doi.org/10.1016/j.celrep.2018.03.072

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TNF blockade induces a dysregulated type I interferon response without autoimmunity in paradoxical psoriasis

Autor: Alexander A. Navarini, Curdin Conrad, Alessio Mylonas, Anne-Karine Lapointe, Jeremy Di Domizio, Olivier Demaria, Michel Gilliet, Cyrine Belkhodja, Lars E. French, Maxime Vernez

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature communications, vol. 9, no. 1, pp. 25

Although anti-tumor necrosis factor (TNF) agents are highly effective in the treatment of psoriasis, 2–5% of treated patients develop psoriasis-like skin lesions called paradoxical psoriasis. The pathogenesis of this side effect and its distinction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbc7decb248c10970a313c075620f0f
https://doaj.org/article/180fc992d72e4fcbbf1d606055e86015

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SARS-CoV-2 ACE-receptor detection in the placenta throughout pregnancy

Autor: Carole Gengler, Laurence de Leval, Estelle Dubruc, Gilbert Greub, David Baud, Guillaume Favre

Publikováno v: Clinical Microbiology and Infection
Clinical microbiology and infection, vol. 27, no. 3, pp. 489-490

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6820416744a3fcd77a50507acf955d5
https://doi.org/10.1016/j.cmi.2020.09.049

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Site-specific absence of microfibrillar-associated protein 4 (MFAP4) from the internal elastic membrane of arterioles in the rheumatoid arthritis synovial membrane:an immunohistochemical study in patients with advanced rheumatoid arthritis versus osteoarthritis

Autor: Christensen, Anne Friesgaard, Sorensen, Grith Lykke, Junker, Kirsten, Revald, Peter, Varnum, Claus, Issa, Saida Farah, Junker, Peter, Sorensen, Flemming Brandt

Publikováno v: Christensen, A F, Sorensen, G L, Junker, K, Revald, P, Varnum, C, Issa, S F, Junker, P & Sorensen, F B 2019, Site-specific absence of microfibrillar-associated protein 4 (MFAP4) from the internal elastic membrane of arterioles in the rheumatoid arthritis synovial membrane : an immunohistochemical study in patients with advanced rheumatoid arthritis versus osteoarthritis . in AMPIS . 8 edn, vol. 127, APMIS Supplementum, pp. 588-593 . https://doi.org/10.1111/apm.12974

Microfibrillar-associated protein 4 (MFAP4) is a non-structural matrix protein with cell regulatory activities and a potential as seromarker for fibrosis. We aimed to study the occurrence of MFAP4 in the synovial membrane from patients with rheumatoi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pure_au_____::1ca6bd99791b937a7a07051819c1f084
https://pure.au.dk/portal/da/publications/sitespecific-absence-of-microfibrillarassociated-protein-4-mfap4-from-the-internal-elastic-membrane-of-arterioles-in-the-rheumatoid-arthritis-synovial-membrane(ef097145-6c87-4367-8dc5-e08652b5a045).html

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Refined Immunochemical Characterization in Healthy Dog Skin of the Epidermal Cornification Proteins, Filaggrin, and Corneodesmosin

Autor: Marie-Christine Cadiergues, Valérie Pendaries, Carine Froment, Guy Serre, Marek Haftek, Emilie Videmont, Sokhna Keita Alassane, Didier Pin, Michel Simon, Nicolas Amalric

Publikováno v: Journal of Histochemistry and Cytochemistry
Journal of Histochemistry and Cytochemistry, Histochemical Society, 2019, 67 (2), pp.85-97. ⟨10.1369/0022155418798807⟩
Journal of Histochemistry and Cytochemistry, 2019, 67 (2), pp.85-97. ⟨10.1369/0022155418798807⟩

International audience; Filaggrin (FLG) and corneodesmosin (CDSN) are two key proteins of the human epidermis. FLG loss-of-function mutations are the strongest genetic risk factors for human atopic dermatitis. Studies of the epidermal distribution of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3448b31d09720a83c6411374cb87c2e3
https://hal-univ-tlse3.archives-ouvertes.fr/hal-03185040

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Effectiveness of biologics in patients with rheumatoid arthritis – a single-center experience

Autor: Marijana Šupe, Ana Gudelj Gračanin, Marko Lucijanić, Jadranka Morović-Vergles

Publikováno v: Reumatizam
Volume 66
Issue 1 (online first)

Pri neučinkovitosti sintetskih lijekova koji modificiraju tijek bolesti (engl. disease-modifying antirheumatic drugs – DMARD s; u tekstu DMARD -i) u liječenju bolesnika s aktivnim reumatoidnim artritisom (RA ) možemo primijeniti jedan od biološ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______951::f71889ba9b26d360c54dafc0f5e4dd7a
https://hrcak.srce.hr/file/329609

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Tracking the amphibian pathogens Batrachochytrium dendrobatidis and Batrachochytrium salamandrivorans using a highly specific monoclonal antibody and lateral-flow technology

Autor: Jamie R. Stevens, Michael J Bungard, Michelle F. O'Brien, Christopher R. Thornton, Andrew E. Bowkett, Michael J. Dillon, Kieran A. Bates, Matthew C. Fisher, Katie M. Beckman

Publikováno v: Dillon, M J, Bowkett, A E, Bungard, M J, Beckmann, K, O'Brien, M F, Bates, K, Fisher, M C, Stevens, J R & Thornton, C R 2017, ' Tracking the amphibian pathogens Batrachochytrium dendrobatidis and Batrachochytrium salamandrivorans using a highly specific monoclonal antibody and lateral-flow technology ', Microbial biotechnology, vol. 10, no. 2, pp. 381-394 . https://doi.org/10.1111/1751-7915.12464
Microbial Biotechnology

Summary The fungus Batrachochytrium dendrobatidis (Bd) causes chytridiomycosis, a lethal epizootic disease of amphibians. Rapid identification of the pathogen and biosecurity is essential to prevent its spread, but current laboratory‐based tests ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d1d8a61acb6a13c5a1f78c1f6d035c
https://doi.org/10.1111/1751-7915.12464

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A value proposition for trough level-based anti-TNFα drug dosing

Autor: E. M. H. Schmitz, Maarten A. C. Broeren, D. van de Kerkhof, Luc J J Derijks, Volkher Scharnhorst

Publikováno v: Clinica Chimica Acta, 489, 89-95. Elsevier

Treatment of inflammatory bowel diseases and rheumatic disorders with anti-tumor necrosis factor alpha (TNFα) drugs is expensive, while a significant proportion of patients does not show adequate clinical response. Therapeutic drug monitoring (TDM)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9702b528150951b8e16ffad0947a3ec1
https://pubmed.ncbi.nlm.nih.gov/30521801

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