Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Antibiotic persistence"'
Autor:
Shuo Yuan, Yamin Shen, Yingying Quan, Shuji Gao, Jing Zuo, Wenjie Jin, Rishun Li, Li Yi, Yuxin Wang, Yang Wang
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Since the discovery of antibiotics, they have served as a potent weapon against bacterial infections; however, natural evolution has allowed bacteria to adapt and develop coping mechanisms, ultimately leading to the concerning escalation of
Externí odkaz:
https://doaj.org/article/4e0753a9916343fea0b45a70c4037886
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Bacterial dormancy is marked by reduced cellular activity and the suspension of growth. It represents a valuable strategy to survive stressful conditions, as exemplified by the long-term tolerance towards antibiotics that is attributable to
Externí odkaz:
https://doaj.org/article/a8c83c82c92b48b39b189dcf9f0092e1
Publikováno v:
mSystems, Vol 9, Iss 11 (2024)
ABSTRACT Bacterial persistence profoundly impacts biofilms, infections, and antibiotic effectiveness. Persister formation can be substantially promoted by nutrient shift, which commonly exists in natural environments. However, mechanisms that promote
Externí odkaz:
https://doaj.org/article/1e680c9b15224e3fb52320ab3ab563e3
Autor:
Jia Hao Yeo, Nasren Begam, Wan Ting Leow, Jia Xuan Goh, Yang Zhong, Yiying Cai, Andrea Lay-Hoon Kwa
Publikováno v:
Microorganisms, Vol 12, Iss 5, p 972 (2024)
Antibiotic resistance is a global health crisis. Notably, carbapenem-resistant Enterobacterales (CRE) pose a significant clinical challenge due to the limited effective treatment options. This problem is exacerbated by persisters that develop upon an
Externí odkaz:
https://doaj.org/article/17bdeea9bb844c379ffba8841cf69916
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Non-genetic factors can cause significant fluctuations in gene expression levels. Regardless of growing in a stable environment, this fluctuation leads to cell-to-cell variability in an isogenic population. This phenotypic heterogeneity allo
Externí odkaz:
https://doaj.org/article/d283cdc9a15b4802adad3a9c8557e36b
Autor:
Alisa Rizvanovic, Charlotte Michaux, Margherita Panza, Zeynep Iloglu, Sophie Helaine, E. Gerhart H. Wagner, Erik Holmqvist
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Bacterial populations can survive exposure to antibiotics through transient phenotypic and gene expression changes. These changes can be attributed to a small subpopulation of bacteria, giving rise to antibiotic persistence. Although this ph
Externí odkaz:
https://doaj.org/article/e5b43f1c7ca441e0b5e3e4000e3e9fe5
Akademický článek
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Akademický článek
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Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Combination treatments are commonly prescribed for enhancing drug efficacy, as well as for preventing the evolution of resistance. The interaction between drugs is typically evaluated near the MIC, using growth rate as a measure of treatment
Externí odkaz:
https://doaj.org/article/4219e7d3412c469ea290bb2dc0d34de4
Akademický článek
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