Výsledky vyhledávání - "Antibiotic failure"

Akademický článek

Dimensionless parameter predicts bacterial prodrug success

Autor: Brandon Alexander Holt, McKenzie Tuttle, Yilin Xu, Melanie Su, Joachim J Røise, Xioajian Wang, Niren Murthy, Gabriel A Kwong

Publikováno v: Molecular Systems Biology, Vol 18, Iss 1, Pp 1-13 (2022)

Abstract Understanding mechanisms of antibiotic failure is foundational to combating the growing threat of multidrug‐resistant bacteria. Prodrugs—which are converted into a pharmacologically active compound after administration—represent a grow

Externí odkaz: https://doaj.org/article/5d6712bdf18742c38cc6ff861bf63f43

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Akademický článek

Neutropenic Fever in Lung Cancer: Clinical Aspects Related to Mortality and Antibiotic Failure

Autor: Inês RODRIGUES, Luísa NASCIMENTO, Ana Cláudia PIMENTA, Sara RAIMUNDO, Bebiana CONDE, Ana FERNANDES

Publikováno v: Chinese Journal of Lung Cancer, Vol 24, Iss 11, Pp 764-769 (2021)

Background and objectives: Lung cancer (LC) is the leading cause of cancer death. Patients treated with chemotherapy are at risk of developing chemotherapy-induced febrile neutropenia (FN), a potentially life-threatening complication. The aims of thi

Externí odkaz: https://doaj.org/article/9bd8aa2930da41dda05db2004e1cf81f

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Akademický článek

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Akademický článek

Mechanisms of Antibiotic Failure During Staphylococcus aureus Osteomyelitis

Autor: Brittney D. Gimza, James E. Cassat

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Staphylococcus aureus is a highly successful Gram-positive pathogen capable of causing both superficial and invasive, life-threatening diseases. Of the invasive disease manifestations, osteomyelitis or infection of bone, is one of the most prevalent,

Externí odkaz: https://doaj.org/article/696371898152493d9026222dad91f8ff

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Akademický článek

Clinical Outcome of Discordant Empirical Therapy and Risk Factors Associated to Treatment Failure in Children Hospitalized for Urinary Tract Infections

Autor: Giovanni Autore, Cosimo Neglia, Margherita Di Costanzo, Martina Ceccoli, Gianluca Vergine, Claudio La Scola, Cristina Malaventura, Alice Falcioni, Alessandra Iacono, Antonella Crisafi, Lorenzo Iughetti, Maria Luisa Conte, Luca Pierantoni, Claudia Gatti, Giacomo Biasucci, Susanna Esposito, UTI-Ped-ER Study Group

Publikováno v: Children, Vol 9, Iss 2, p 128 (2022)

With the spread of antibiotic resistance in pediatric urinary tract infections (UTIs), more patients are likely to be started empirically on antibiotics to which pathogens are later found to be resistant (discordant therapy). However, in-vivo effecti

Externí odkaz: https://doaj.org/article/c86f22c6fa6648f3bf806462c206487c

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Akademický článek

A cost analysis of a broad-spectrum antibiotic therapy in the empirical treatment of health care-associated infections in cirrhotic patients

Autor: Lucidi C, Di Gregorio V, Ceccarelli G, Venditti M, Riggio O, Merli M

Publikováno v: ClinicoEconomics and Outcomes Research, Vol Volume 9, Pp 385-390 (2017)

Cristina Lucidi,1 Vincenza Di Gregorio,1 Giancarlo Ceccarelli,2 Mario Venditti,2 Oliviero Riggio,1 Manuela Merli1 1Gastroenterology, Department of Clinical Medicine, Sapienza University of Rome, Rome, Italy; 2Department of Public Health and Infectiou

Externí odkaz: https://doaj.org/article/649c27b4ea464b739a39d1cfb193e9e0

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