Výsledky vyhledávání - "Anti-leishmanial"

Akademický článek

In vitro antileishmanial activity of ozone against Leishmania major

Autor: Ali Salmani, Mahdi Delavari, Mohsen Arbabi

Publikováno v: International Archives of Health Sciences, Vol 11, Iss 3, Pp 173-177 (2024)

Objectives: This research aimed to investigate the impact of ozone on Leishmania major.Methods: Leishmania major promastigotes were exposed to ozone flow at varying concentrations (5, 10, 20, 30, and 40 ppm) for different durations (5, 10, 20, 30, an

Externí odkaz: https://doaj.org/article/3c6c134c8b654a769a78f02b3d8f18fb

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Akademický článek

In vitro and in vivo anti-parasitic activity of curcumin nanoemulsion on Leishmania major (MRHO/IR/75/ER)

Autor: Keivan Sahebi, Fatemeh Shahsavani, Fatemeh Mehravar, Gholamreza Hatam, Rasoul Alimi, Amirhossein Radfar, Mohammad Saleh Bahreini, Ali Pouryousef, Aref Teimouri

Publikováno v: BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-8 (2024)

Abstract The present study aimed to assess the anti-leishmanial effects of curcumin nanoemulsion (CUR-NE) against Leishmania major (MRHO/IR/75/ER) in both in vitro and in vivo experiments. CUR-NE was successfully prepared via the spontaneous emulsifi

Externí odkaz: https://doaj.org/article/afaf97dbcc75497992cab4b31e9f9b9c

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Akademický článek

Cocrystals of a coumarin derivative: an efficient approach towards anti-leishmanial cocrystals against MIL-resistant Leishmania tropica

Autor: Muhammad Shahbaz, Saba Farooq, M. Iqbal Choudhary, Sammer Yousuf

Publikováno v: IUCrJ, Vol 11, Iss 2, Pp 224-236 (2024)

Leishmaniasis is a neglected parasitic tropical disease with numerous clinical manifestations. One of the causative agents of cutaneous leishmaniasis (CL) is Leishmania tropica (L. tropica) known for causing ulcerative lesions on the skin. The advers

Externí odkaz: https://doaj.org/article/296690fbdbfa4b8c9ec943c27ac715db

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Akademický článek

Molecular docking and synthesis of N-alkyl-isatin-3-imino aromatic amine derivatives and their antileishmanial and cytotoxic activities

Autor: Farshid Hassanzadeh, Seyed Hossein Hejazi, Elham Jafari, Atefeh Mohammadi fard, Hojjat Sadeghi-aliabadi

Publikováno v: Research in Pharmaceutical Sciences, Vol 19, Iss 2, Pp 238-250 (2024)

Background and purpose: Isatin derivatives have excited attention due to their biological attractions, especially, anticancer properties. Isatin analogs such as semaxanib and sunitinib were exposed to tyrosine kinase inhibitory properties. N-substitu

Externí odkaz: https://doaj.org/article/e06368f26a524e51ba71f8de4abe1489

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Akademický článek

Liposomal dual delivery systems in visceral leishmaniasis enhance the synergistic effects of combination therapy: A promise for the future

Autor: Raghunath Hazra, Amrita Kar, Santanu Kar Mahapatra

Publikováno v: Asian Pacific Journal of Tropical Medicine, Vol 17, Iss 2, Pp 47-60 (2024)

Visceral leishmaniasis (VL) is a neglected tropical disease, and this review has summarized the current treatment scenario and its prospects. It also highlights alternative approaches used by research groups in India and around the world to develop c

Externí odkaz: https://doaj.org/article/fa2930f6ebaf4d3bb0bd78093eae3af7

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Akademický článek

Phytochemical profiling, antimicrobial, antibiofilm, insecticidal, and anti-leishmanial properties of aqueous extract from Juglans regia L. root bark: In vitro and in silico approaches

Autor: Ali Ellafi, Racha Farhat, Mejdi Snoussi, Emira Noumi, El Hassane Anouar, Ridha Ben Ali, Michèle Véronique El May, Sami Sayadi, Kaïss Aouadi, Adel Kadri, Sonia Ben Younes

Publikováno v: International Journal of Food Properties, Vol 26, Iss 1, Pp 1079-1097 (2023)

ABSTRACTThe Juglans regia root aqueous extract (JRRAE) phytochemical variability and the investigation of their antimicrobial, antibiofilm, insecticidal, and anti-leishmanial properties were studied. As a result, the JRRAE chemical profile revealed t

Externí odkaz: https://doaj.org/article/e54b0d4bdb2e4b12922b06cdddd0c72c

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Akademický článek

Aurantoside L, a New Tetramic Acid Glycoside with Anti-Leishmanial Activity Isolated from the Marine Sponge Siliquariaspongia japonica

Autor: Yasumoto Oyadomari, Yasuyuki Goto, Keisuke Suganuma, Shin-ichiro Kawazu, Leontine E. Becking, Nobuhiro Fusetani, Yoichi Nakao

Publikováno v: Marine Drugs, Vol 22, Iss 4, p 171 (2024)

A new tetramic acid glycoside, aurantoside L (1), was isolated from the sponge Siliquariaspongia japonica collected at Tsushima Is., Nagasaki Prefecture, Japan. The structure of aurantoside L (1) composed of a tetramic acid bearing a chlorinated poly

Externí odkaz: https://doaj.org/article/466cd7399c8d423588fbfb3ba5df8485

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Akademický článek

In vitro Anti-Leishmanial Activities of Methanol Extract of Brucea antidysenterica J.F. Mill Seeds and Its Solvent Fractions

Autor: Ketema T, Tadele M, Gebrie Z, Makonnen E, Hailu A, Abay SM

Publikováno v: Journal of Experimental Pharmacology, Vol Volume 15, Pp 123-135 (2023)

Tasisa Ketema,1 Markos Tadele,2 Zewdie Gebrie,1 Eyasu Makonnen,1,3 Asrat Hailu,3,4 Solomon M Abay1 1Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Science, Addis Ababa University, Addis Ababa, Ethiopia; 2Anima

Externí odkaz: https://doaj.org/article/22c445d870ef4e44bb65a95b897b21d5

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