Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment

Autor: Silvia Gobbi, Alessandra Bisi, Letizia Pruccoli, Manuela Bartolini, Ignacio Moraleda, Serena Montanari, Marina Naldi, Sabrina Petralla, Barbara Monti, Alessia Ligresti, Isabel Iriepa, Alessandro Rabbito, Vincenzo Di Marzo, Ali M. Mahmoud, Federica Belluti, Andrea Tarozzi, Angela Rampa

Publikováno v: European journal of medicinal chemistry 178 (2019): 243–258. doi:10.1016/j.ejmech.2019.05.080
info:cnr-pdr/source/autori:Montanari, Serena; Mahmoud, Ali Mokhtar; Pruccoli, Letizia; Rabbito, Alessandro; Naldi, Marina; Petralla, Sabrina; Moraleda, Ignacio; Bartolini, Manuela; Monti, Barbara; Iriepa, Isabel; Belluti, Federica; Gobbi, Silvia; Di Marzo, Vincenzo; Bisi, Alessandra; Tarozzi, Andrea; Ligresti, Alessia; Rampa, Angela/titolo:Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment/doi:10.1016%2Fj.ejmech.2019.05.080/rivista:European journal of medicinal chemistry/anno:2019/pagina_da:243/pagina_a:258/intervallo_pagine:243–258/volume:178
European Journal of Medicinal Chemistry

To address the multifactorial nature of Alzheimer's Disease (AD), a multi-target-directed ligand approach was herein developed. As a follow-up of our previous studies, a small library of newly designed 2-arylbenzofuran derivatives was evaluated towar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa055218c5b73e3c7255d06e2d5ed41
https://doi.org/10.1016/j.ejmech.2019.05.080

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