Zobrazeno 1 - 10
of 1 912
pro vyhledávání: '"Anti-cancer drug"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 179, Iss , Pp 117356- (2024)
Protein neddylation, a type of post-translational modifications, involves the transfer of the ubiquitin-like protein NEDD8 to the lysine residues of a target substrate, which is catalyzed by the NEDD8 activating enzyme (E1), NEDD8 conjugating enzyme
Externí odkaz:
https://doaj.org/article/8f51bf3e2a15428b88cdde70f8e82e8d
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5178-5193 (2024)
Histone deacetylase 9 (HDAC9) is known to be upregulated in various cancers. Cancer-associated antigens (CAGEs) are cancer/testis antigens that play an important role in anti-cancer drug resistance. This study aimed to investigate the relationship be
Externí odkaz:
https://doaj.org/article/9dd815432e864cd188e5daf6888066f8
Autor:
Eugene V. Makeyev, Sui Huang
Publikováno v:
Nucleus, Vol 15, Iss 1 (2024)
The perinucleolar compartment (PNC) was initially identified as a nuclear structure enriched for the polypyrimidine tract-binding protein. Since then, the PNC has been implicated in carcinogenesis. The prevalence of this compartment is positively cor
Externí odkaz:
https://doaj.org/article/12343826ce5a417ea5c74cf443e7840d
Publikováno v:
Cancer Reports, Vol 7, Iss 5, Pp n/a-n/a (2024)
Abstract Background Statins, frequently prescribed medications, work by inhibiting the rate‐limiting enzyme HMG‐CoA reductase (HMGCR) in the mevalonate pathway to reduce cholesterol levels. Due to their multifaceted benefits, statins are being ad
Externí odkaz:
https://doaj.org/article/33a0cbdfe84b4227bd4c874c3678eb3d
Autor:
Chenchen He, Linlin Ma, Jeff Hirst, Fei Li, Hao Wu, Wang Liu, Jiang Zhao, Feng Xu, Andrew K. Godwin, Xiangwei Wang, Benyi Li
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionAlternol is a natural compound isolated from the fermentation of a mutated fungus. We have demonstrated its potent anti-cancer effect via the accumulation of radical oxygen species (ROS) in prostate cancer cells in vitro and in vivo. In t
Externí odkaz:
https://doaj.org/article/bb74bb9f5b694e3db95c11a1ed625183
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/171fac00c2d74d75839ab8553a4ddf18
Autor:
Saied Jamaladdin Emamjome Koohbanani, Sayed Ali Ahmadi, Dadkhoda Ghazanfari, Enayatollah Sheikhhosseini
Publikováno v:
Carbon Trends, Vol 14, Iss , Pp 100332- (2024)
Axitinib, marketed as Inlyta, finds various medical applications in the treatment of conditions such as breast cancer, myeloid leukemia, and juvenile myelomonocytic leukemia. Initially, the synthesis of this cytidine analog, and its deoxy derivative
Externí odkaz:
https://doaj.org/article/6e80d5c2682e43438fb89fccd4ee815a
Publikováno v:
علوم و تکنولوژی پلیمر, Vol 36, Iss 2, Pp 167-176 (2023)
Hypothesis: Due to the alternating hydroxyl and secondary amine groups, the polymer poly(1-(2-((3-amino-2-hydroxypropyl)amino)ethyl)-1'-ethyl-[4,4'-bipyridine]-1,1'-diium) (poly(AHAEBD)), is highly prone to complex formation. In this case, iron (III)
Externí odkaz:
https://doaj.org/article/d943883ec5a542249345193ed4df6866
Publikováno v:
IET Nanobiotechnology, Vol 17, Iss 4, Pp 326-336 (2023)
Abstract In nanotechnology, compounds containing metal materials are used in pharmaceutical sciences. The main purpose of this research was to introduce a novel method to control the amount of zeolite imidazolate framework (ZIF) in water by forming a
Externí odkaz:
https://doaj.org/article/f206d93f8121416f8a1bc6f5485f8b6d
Autor:
Biuck Habibi, Sara Pashazadeh
Publikováno v:
Sensing and Bio-Sensing Research, Vol 42, Iss , Pp 100604- (2023)
In this research, the synthesis, fabrication steps and characterization of a new modified glassy carbon electrode (GCE) with CuFe2O4 magnetic nanoparticles combined with zeolitic imidazolate framework (ZIF-8) embedded graphene quantum dots (GQDs), (C
Externí odkaz:
https://doaj.org/article/cf7d89feb1014fb0bef21983d982687b