Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Anti-Carcinoembryonic Antigen Antibody"'
Publikováno v:
The Journal of surgical research. 218
BackgroundThe success of a curative surgery for cancer is dependent on the complete removal of all cancer cells. Tumor visualization by the surgeon can be enhanced through fluorescent-antibody targeting. To further develop such technology, we selecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422d27185254b599dcf6afc83b729001
https://pubmed.ncbi.nlm.nih.gov/28985840
https://pubmed.ncbi.nlm.nih.gov/28985840
Autor:
Yuji Watanabe, Takeshi Imamura, Shigehiro Koga, Koichi Sato, Tadahiro Iimura, Atsuhiko Hikita, Kenji Kameda, Motohira Yoshida, Naoki Honkura, Yuji Yamamoto, Yusuke Oshima
Publikováno v:
Cancer Science
Recently, there has been growing interest in applying fluorescence imaging techniques to the study of various disease processes and complex biological phenomena in vivo. To apply these methods to clinical settings, several groups have developed proto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bafa3c7011d95cbddeb63c8f2ba64626
https://doi.org/10.1111/cas.12500
https://doi.org/10.1111/cas.12500
Autor:
Eric Frampas, Philippe Thedrez, Patricia Remaud-Le Saëc, Alain Faivre-Chauvet, Jacques Barbet, Catherine Maurel
Publikováno v:
Nuclear Medicine Communications. 32:147-154
Background Radioimmunotherapy is emerging as a new tool for adjuvant therapy of colorectal cancer. The liver remains the main site for metastases, carrying a high mortality rate. Many animal models are available but none associates easy, reliable imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a294f2c98dcef3445259d0d5b83e30a
https://doi.org/10.1097/mnm.0b013e328341b268
https://doi.org/10.1097/mnm.0b013e328341b268
Publikováno v:
Cancer Immunology, Immunotherapy. 57:1879-1890
Theoretical analyses suggest that the cellular internalization and catabolism of bound antibodies contribute significantly to poor penetration into tumors. Here we quantitatively assess the internalization of antibodies and antibody fragments against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47e7976973500881c76836f3d3910cb
https://doi.org/10.1007/s00262-008-0518-1
https://doi.org/10.1007/s00262-008-0518-1
Publikováno v:
International Journal of Cancer. 100:367-374
Production of recombinant antibody fragments in bacterial expression systems results in intentional or fortuitous differences compared to the original products prepared by hybridoma technology. These differences may have significant effects not only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4e9f921ef9491dc20e93164192e97be
https://doi.org/10.1002/ijc.10477
https://doi.org/10.1002/ijc.10477
Autor:
Ali Maawy, Sharmeela Kaushal, Yukihiko Hiroshima, Robert M. Hoffman, Michael Bouvet, George A. Luiken
Publikováno v:
Journal of biomedical optics, vol 18, iss 12
The aim of this study was to evaluate a set of visible and near-infrared dyes conjugated to a tumor-specific chimeric antibody for high-resolution tumor imaging in orthotopic models of pancreatic cancer. BxPC-3 human pancreatic cancer was orthotopica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ad7c00390f0a418a3c50e5cfc1fded
https://europepmc.org/articles/PMC3868446/
https://europepmc.org/articles/PMC3868446/
Publikováno v:
Bioorganic & Medicinal Chemistry. 3:1305-1312
Doxorubicin was modified with five different heterobifunctional reagents to produce drug analogs containing 3'-N-amide or C-13 hydrazone linkage with maleimide. Synthesis and characterization of two new reagents, 4-maleimidobenzohydrazide trifluoroac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42b562cedda334e60d982d95a9b6f98
https://doi.org/10.1016/0968-0896(95)00126-2
https://doi.org/10.1016/0968-0896(95)00126-2
Autor:
Suresh C. Srivastava, Jean-François Chatal, Jean-François Gestin, Alain Faivre-Chauvet, George E. Meinken, Ronnie C. Mease, M. A. Slinkin, Catherine Saï-Maurel, Philippe Thedrez
Publikováno v:
Nuclear Medicine and Biology. 20:755-762
The purpose of this study was to synthesize new bifunctional linker-chelating agents for the modification of the in vivo distribution of 111 In-labeled antibodies. A general simple synthetic method of preparing cyclohexyl EDTA (CDTA) derivatives cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e6855743e626c493009bf68b301cf6
https://doi.org/10.1016/0969-8051(93)90162-n
https://doi.org/10.1016/0969-8051(93)90162-n
Autor:
Jason L. J. Dearling, Uzma Qureshi, Elena F. Fidarova, Klaus R. Trott, Ethaar El-Emir, Mathew Robson, R. Barbara Pedley, Richard H. J. Begent, Geoffrey M. Boxer
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 14(9)
Purpose: Most radioimmunotherapy studies on radiolabeled antibody distribution are based on autoradiographic and radioluminographic data, which provide a lack of detailed information due to low resolution. We used fluorescently labeled anti–carcino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9400b079cd6cd3df80491327f8d6c1f
https://pubmed.ncbi.nlm.nih.gov/18451227
https://pubmed.ncbi.nlm.nih.gov/18451227
Autor:
Clare Cruickshank, John A. Hartley, Berend Tolner, Alan J. Green, Julie Wren, Geoff Boxer, Surinder K. Sharma, A Mayer, Jan Martin, Richard H. J. Begent, Roslyn J. Francis, Caroline J. Springer, Jimmy D. Bell, Kerry A. Chester
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 12(21)
Purpose: Antibody-directed enzyme prodrug therapy is a two-stage treatment whereby a tumor-targeted antibody-enzyme complex localizes in tumor for selective conversion of prodrug. The purpose of this study was to establish optimal variables for singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed3680d6afd8a53b5698f90bd1ad4cf
https://pubmed.ncbi.nlm.nih.gov/17085666
https://pubmed.ncbi.nlm.nih.gov/17085666