Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Anthrapyrazoles"'
Akademický článek
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Publikováno v:
Computational Chemistry. :17-26
QSAR methodology was used to assess the effects of lipophilicity (logP), molar volume (MV) and polarizability (pl) of the side chains at N2 and C5 of 20 known desoxy anthrapyrazoles on their in vitro anticancer activity expressed as the negative loga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::961024fce4dd6fa9f08be65a7168860e
https://doi.org/10.4236/cc.2020.82003
https://doi.org/10.4236/cc.2020.82003
Autor:
Marcin Gackowski, Karolina Szewczyk-Golec, Robert Pluskota, Marcin Koba, Katarzyna Mądra-Gackowska, Alina Woźniak
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 5132
An approach using multivariate adaptive regression splines (MARSplines) was applied for quantitative structure–activity relationship studies of the antitumor activity of anthrapyrazoles. At the first stage, the structures of anthrapyrazole derivati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d9ad1ae0118eafc930b815f8c02df1
https://pubmed.ncbi.nlm.nih.gov/35563523
https://pubmed.ncbi.nlm.nih.gov/35563523
Ο σκοπός της παρούσας διπλωματικής εργασίας είναι η ανάπτυξη νέων ανθραπυραζολικών παραγώγων και των συμπλόκων τους με τρικαρβονυλικό
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb84f408219edc90eb1d12cddb6a84c9
Akademický článek
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Autor:
David F. Wiemer, MeeKyoung Kim
Publikováno v:
Tetrahedron Letters. 45:4977-4980
The EDC-mediated condensation of 1-chloro-5-hydrazino-9,10-anthracenedione afforded an N-1 acyl anthrapyrazole instead of the expected hydrazide. The regiochemistry of the N-acyl substituent was assigned on the basis of an extensive set of NMR experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6018462ac6b3452acb30f394de2384d5
https://doi.org/10.1016/j.tetlet.2004.04.041
https://doi.org/10.1016/j.tetlet.2004.04.041
Publikováno v:
Journal of Heterocyclic Chemistry. 37:47-55
The synthesis of several N-tert-butoxycarbonyl(Boc)-protected-N-substituted hydrazines has been accomplished. The use of these protected hydrazines in SNAr substitutions leads to products in which the most nucleophilic nitrogen displaces the leaving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db1b437d2644caaae578d99ed9da292a
https://doi.org/10.1002/jhet.5570370108
https://doi.org/10.1002/jhet.5570370108
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 10(8)
We have synthesized a series of anthrapyrazoles derivatives. The biological results indicated that these derivatives exhibited potent in vitro cytotoxicity against different cancer cell lines (human hepatocellular carcinoma HepG2 and BEL-7402, human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ac08d11eb31c34ff259c215f81b158
https://pubmed.ncbi.nlm.nih.gov/24773347
https://pubmed.ncbi.nlm.nih.gov/24773347
Autor:
Janine Mansi, Helen Gogas
Publikováno v:
Cancer Treatment Reviews. 21:541-552
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff8197bfbd49d6a923e61f29a35b7c62
https://doi.org/10.1016/0305-7372(95)90017-9
https://doi.org/10.1016/0305-7372(95)90017-9
Autor:
Monica Tortoreto, Rosanna Supino, Raffaella Pavesi, Federica Facchinetti, Laura Dal Bo, Gabriella Pezzoni, Ernesto Menta, Silvia Richter, Dante Torriani, Claudia Sissi, Donatella Polizzi, Nives Carenini, Giovanni Capranico, Manlio Palumbo, Silvano Spinelli, Gino Beggiolin, Fulvio Guano, Franco Zunino, Graziella Pratesi
Objectives: Systematic investigation of a novel series of intercalating agents, 9-aza-anthrapyrazoles, has led to the identification of a promising analogue, BBR 3438. This study describes the antitumour efficacy of the novel compound in human prosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823e34adb6d76ca739b679a41c8393d0
http://hdl.handle.net/11577/2467700
http://hdl.handle.net/11577/2467700