Výsledky vyhledávání - "Anthony Wing-ip Lo"

Akademický článek

Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

The tumor microenvironment can influence patient survival response to therapy. Here, the authors used single-cell sequencing to investigate the microenvironment of nasopharyngeal cancer and identify tumor-specific signatures in five stromal clusters

Externí odkaz: https://doaj.org/article/0b2c6fcf4f674aa2b645939100155c52

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Akademický článek

Efficacy, safety, and correlative biomarkers of bintrafusp alfa in recurrent or metastatic nasopharyngeal cancer patients: a phase II clinical trialResearch in context

Publikováno v: The Lancet Regional Health. Western Pacific, Vol 40, Iss , Pp 100898- (2023)

Summary: Background: The strategy of dual blockade of TGF-β and PD-L1 pathways has not been previously tested in platinum-refractory recurrent or metastatic nasopharyngeal cancer (R/M NPC) patients. This study aimed to evaluate the safety and effica

Externí odkaz: https://doaj.org/article/8a4c0f1c23f14e66b633df5f0add5a87

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Akademický článek

Predicting oral cancer risk in patients with oral leukoplakia and oral lichenoid mucositis using machine learning

Autor: John Adeoye, Mohamad Koohi-Moghadam, Siu-Wai Choi, Li-Wu Zheng, Anthony Wing Ip Lo, Raymond King-Yin Tsang, Velda Ling Yu Chow, Abdulwarith Akinshipo, Peter Thomson, Yu-Xiong Su

Publikováno v: Journal of Big Data, Vol 10, Iss 1, Pp 1-24 (2023)

Abstract Oral cancer may arise from oral leukoplakia and oral lichenoid mucositis (oral lichen planus and oral lichenoid lesions) subtypes of oral potentially malignant disorders. As not all patients will develop oral cancer in their lifetime, the av

Externí odkaz: https://doaj.org/article/f18f545ec3b54e3c9ea5ba566b9c6927

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Peritumoral B cells drive proangiogenic responses in HMGB1-enriched esophageal squamous cell carcinoma

Autor: Ying Wang, Reshma Shakya, Anthony Wing Ip Lo, Rajiv Khanna, Ka Chun Wu, Xin Yuan Guan, Leo Y. C. Yan, Dora L.W. Kwong, Yanru Qin, Wei Dai, Simon Law, Ngar-Woon Kam, Victor Ho-Fun Lee

Publikováno v: Angiogenesis

Several B-cell subsets with distinct functions and polarized cytokine profiles that extend beyond antibody production have been reported in different cancers. Here we have demonstrated that proliferating B cells were predominantly found in the peritu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4695a893e3aa9e3fcc155bc54348ecf
http://europepmc.org/articles/PMC8494172

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Abstract 363: Modelling cancer cachexia using a comprehensive panel of heterogeneous esophageal squamous cell carcinoma xenografts for therapeutic application

Autor: Bryan Chee-chad Lung, Valen Zhuoyou Yu, Ian Yu-hong Wong, Claudia Lai-yin Wong, Desmond Kwan-kit Chan, Fion Siu-yin Chan, Betty Tsz-ting Law, Ka-on Lam, Dora Lai-wan Kwong, Anthony Wing-ip Lo, Simon Law, Maira Li Lung

Publikováno v: Cancer Research. 83:363-363

Background: Esophageal squamous cell carcinoma (ESCC) is one of deadliest esophageal malignancies in Asia. Cancer cachexia is a multifactorial body wasting syndrome and is one of the major causes of death in late-stage patients (1). It is characteriz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b51c63a2a931bafbb35fdfbfb2870317
https://doi.org/10.1158/1538-7445.am2023-363

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Clonal relationship and alcohol consumption-associated mutational signature in synchronous hypopharyngeal tumours and oesophageal squamous cell carcinoma

Autor: Josephine Mun-Yee Ko, Chen Guo, Conghui Liu, Lvwen Ning, Wei Dai, Lihua Tao, Anthony Wing-Ip Lo, Carissa Wing-Yan Wong, Ian Yu-Hong Wong, Fion Siu-Yin Chan, Claudia Lai-Yin Wong, Kwan Kit Chan, Tsz Ting Law, Nikki Pui-Yue Lee, Zhichao Liu, Haoyao Jiang, Zhigang Li, Simon Law, Maria Li Lung

Publikováno v: British journal of cancer. 127(12)

Background The patients with dual oesophageal squamous cell carcinoma (ESCC) and hypopharyngeal cancer (HPC) have poor prognosis; their underlying genetic pathogenesis is unclear. We hypothesise that development of synchronous ESCC/HPC depends on mul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8531a6cce1364498fca67456086653d
https://pubmed.ncbi.nlm.nih.gov/36261585

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SMARCB1 (INI-1)-Deficient Sinonasal Carcinoma: A Systematic Review and Pooled Analysis of Treatment Outcomes

Autor: Victor Ho-Fun Lee, Raymond King-Yin Tsang, Anthony Wing Ip Lo, Sum-Yin Chan, Joseph Chun-Kit Chung, Chi-Chung Tong, To-Wai Leung, Dora Lai-Wan Kwong

Publikováno v: Cancers. 14:3285

(1) Background: SMARCB1 (INI-1)-deficient sinonasal carcinoma is a rare sinonasal malignancy; since its discovery and description in 2014, less than 200 cases have been identified. It is almost impossible to perform randomized-controlled trials on no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea17d949573b5226f9699f2b7d8a2ae
https://doi.org/10.3390/cancers14133285

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Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma

Publikováno v: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

The tumor microenvironment (TME) of nasopharyngeal carcinoma (NPC) harbors a heterogeneous and dynamic stromal population. A comprehensive understanding of this tumor-specific ecosystem is necessary to enhance cancer diagnosis, therapeutics, and prog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02cb14bf2f435c152099305ed517828
http://europepmc.org/articles/PMC7943808

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