Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anthony W. Frei"'
Autor:
Ying Li, Anthony W. Frei, Irayme M. Labrada, Yanan Rong, Jia-Pu Liang, Magdalena M. Samojlik, Chuqiao Sun, Steven Barash, Benjamin G. Keselowsky, Allison L. Bayer, Cherie L. Stabler
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Allogeneic islet transplantation is a promising cell-based therapy for Type 1 Diabetes (T1D). The long-term efficacy of this approach, however, is impaired by allorejection. Current clinical practice relies on long-term systemic immunosuppression, le
Externí odkaz:
https://doaj.org/article/320ef7a04b384cbfa75532b3502888b2
Autor:
Ying, Li, Anthony W, Frei, Ethan Y, Yang, Irayme, Labrada-Miravet, Chuqiao, Sun, Yanan, Rong, Magdalena M, Samojlik, Allison L, Bayer, Cherie L, Stabler
Publikováno v:
Biomaterials
The curative potential of non-autologous cellular therapy is hindered by the requirement of anti-rejection therapy. Cellular encapsulation within nondegradable biomaterials has the potential to inhibit immune rejection, but the efficacy of this appro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5e4e32ffd938d12817b1503c48e1fa6
https://pubmed.ncbi.nlm.nih.gov/32599358
https://pubmed.ncbi.nlm.nih.gov/32599358
Autor:
Chuqiao Sun, Cherie L. Stabler, Magdalena M. Samojlik, Ying Li, Anthony W. Frei, Yanan Rong, Allison L. Bayer, Irayme Labrada-Miravet, Ethan Y. Yang
Publikováno v:
Biomaterials. 256:120182
Cell replacement therapy has the potential to cure diseases caused by the absence or malfunction of specialized cells. A substantial impediment to the success of any non-autologous cellular transplant is the need for systemic immunosuppressive drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c354099a81db21e99e2ff36b434f2d93
https://doi.org/10.1016/j.biomaterials.2020.120182
https://doi.org/10.1016/j.biomaterials.2020.120182
Publikováno v:
Diabetes. 67
Clinical islet transplantation (CIT) is a potential therapy for type 1 diabetes. Allorejection mediated by the host CD4 T cells is a major hurdle for successful CIT, despite potent systemic immunosuppression (SI). To address these issues, we engineer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c95a2e7aa4b0ec271993c788100845bc
https://doi.org/10.2337/db18-31-or
https://doi.org/10.2337/db18-31-or
Publikováno v:
Journal of tissue engineering and regenerative medicine. 12(2)
The local delivery of immunosuppressive agents could significantly promote the success of islet transplantation for the treatment of Type 1 diabetes. Fingolimod, a clinically-approved sphingosine-1-phosphate receptor agonist, has been found to dampen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321fb9c85a4e1bb9abc538c4a218d8f7
https://pubmed.ncbi.nlm.nih.gov/28486786
https://pubmed.ncbi.nlm.nih.gov/28486786
Autor:
Cherie L. Stabler, Anthony W. Frei
Publikováno v:
Bio-inspired Materials for Biomedical Engineering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bdadbe249edb227bc36c597d679906b
https://doi.org/10.1002/9781118843499.ch17
https://doi.org/10.1002/9781118843499.ch17
Interpenetrating network (IPN) hydrogels were recently introduced to the cartilage tissue engineering literature, with the approach of encapsulating cells in thermally gelling agarose that is then soaked in a poly(ethylene glycol) diacrylate (PEGDA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d971795ed8f5d27ce0cde412f0bb373b
https://europepmc.org/articles/PMC3638541/
https://europepmc.org/articles/PMC3638541/