Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Anthony W. Bannon"'
Autor:
Stephen, Zicha, Randall J, Bateman, Leslie M, Shaw, Henrik, Zetterberg, Anthony W, Bannon, Wesley A, Horton, Mike, Baratta, Hartmuth C, Kolb, Iwona, Dobler, Yulia, Mordashova, Ziad S, Saad, David L, Raunig, Emmanouil Manos, Spanakis, Yan, Li, Suzanne E, Schindler, Kyle, Ferber, Carrie E, Rubel, Robert L, Martone, Christopher J, Weber, Rebecca M, Edelmayer, Emily A, Meyers, James G, Bollinger, Erin G, Rosenbaugh, William Z, Potter
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's AssociationREFERENCES.
This report details the approach taken to providing a dataset allowing for analyses on the performance of recently developed assays of amyloid beta (Aβ) peptides in plasma and the extent to which they improve the prediction of amyloid positivity.Alz
Autor:
Rosemarie Roeloffs, Anthony W Bannon, Adam R. Brown, Alexandre J.C. Loucif, Aristos J. Alexandrou, Anthony J. Kirkup, Mathew D Fuller, Gillian Stockbridge, Edward B. Stevens, David Printzenhoff, Praveen Anand, Steve England, Claire Elizabeth Payne, Uma Anand, Peter J. Bungay, Aaron C. Gerlach, Mark L. Chapman, Kemp Mark Ian, John H. Mahoney, Rebecca L. Prime, Jonathon W Theile, Brett M Antonio, Richard P. Butt, Sharan K. Bagal
Publikováno v:
British Journal of Pharmacology. 172:2654-2670
Background and Purpose NaV1.8 ion channels have been highlighted as important molecular targets for the design of low MW blockers for the treatment of chronic pain. Here, we describe the effects of PF-01247324, a new generation, selective, orally bio
Autor:
Balu Kamaraj, Yingtao Bi, Simon Xi, Amit Das, Viswanath Devanarayan, Smriti Mishra, Matt Townsend, Philge Philip, Anthony W. Bannon, M.I. Shah, Gyan Srivastava, Sudeshna Das, Amitava Bhattacharyya, Brinda Ravikumar
Publikováno v:
Alzheimer's & Dementia. 15:P1588-P1588
Autor:
Douglas S. Krafte, Anthony W Bannon
Publikováno v:
Current Opinion in Pharmacology. 8:50-56
Recent scientific advances have enhanced our understanding of the role voltage-gated sodium channels play in pain sensation. Human data on Nav1.7 show that gain-of-function mutations lead to enhanced pain while loss-of-function mutations lead to Cong
Autor:
Tie J. Zhang, James W. Davis, Di Bian, Jean-Claude Louis, Dawn Zhu, Anthony W. Bannon, Kenneth D. Wild
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 322:282-287
A considerable body of evidence implicates endogenous nerve growth factor (NGF) in conditions in which pain is a prominent feature, including neuropathic pain. However, previous studies of NGF antagonism in animal models of neuropathic pain have exam
Autor:
Carlo van Staden, Clarence Hale, Faye Hsieh, Vu Van Ma, Anthony W. Bannon, John A. Salon, Christopher Hulme, Kirk Rorrer, Paul Tempest, Jamie Baumgartner
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:5066-5072
Melanin-concentrating hormone (MCH) is a cyclic 19 amino acid orexigenic neuropeptide. The action of MCH on feeding is thought to involve the activation of its respective G protein-coupled receptor MCH-R1. Consequently, antagonists that block MCH reg
Autor:
Nuria A. Tamayo, Shimin Xu, Michael G. Kelly, Duncan M. Smith, Ning Chen, Michelle Carmouche, Mark H. Norman, Martin H. Goldberg, James Davis, Christopher H. Fotsch, Clarence Hale, Ning Xi, Markian Stec, James W. Baumgartner, Premilla Arasasingham, Nianhe Han, Feng-Yin Hsieh, Qingyian Liu, Yunxin Bo, Anthony W. Bannon
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:1623-1627
The biological activity for a set of melanocortin-4 receptor (MC4R) agonists containing a piperazine core with an ortho-substituted aryl sulfonamide is described. Compounds from this set had binding and functional activities at MC4R less than 30 nM.
Autor:
Narender R. Gavva, James J. S. Treanor, Todd W. Vanderah, Yusheng Qu, Jean Claude Louis, Tie J. Zhang, Frank Porreca, Kenneth D. Wild, Elizabeth M. Doherty, Rami Tamir, David C. Immke, Anthony W. Bannon, Mark H. Norman, Lana Klionsky, Judy Wang, Dawn Zhu
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 313:474-484
The vanilloid receptor 1 (VR1 or TRPV1) is a membrane-bound, nonselective cation channel expressed by peripheral sensory neurons. TRPV1 antagonists produce antihyperalgesic effects in animal models of inflammatory and neuropathic pain. Here, we descr
Autor:
James Davis, William J. Boyle, Anthony W. Bannon, Vickie E. Baracos, David L. Lacey, Xiaolan Zhou, H.Q. Han, Vered Solomon, Keith Soo-Nyung Kwak
Publikováno v:
Cancer Research. 64:8193-8198
The progressive depletion of skeletal muscle is a hallmark of many types of advanced cancer and frequently is associated with debility, morbidity, and mortality. Muscle wasting is primarily mediated by the activation of the ubiquitin-proteasome syste
Autor:
Karen L. Gunther, Elizabeth A. Kowaluk, Kathy L. Kohlhaas, Anthony W. Bannon, James J Lynch, Michael F. Jarvis
Publikováno v:
Pharmacology Biochemistry and Behavior. 63:83-91
Adenosine (ADO) is an inhibitory neuromodulator that can increase the nociceptive threshold in animals exposed to a variety of noxious stimuli. Inhibition of the ADO-metabolizing enzyme, ADO kinase (AK), provides a means of locally enhancing extracel