How well can in vitro data predict in vivo effects of chemicals? Rodent carcinogenicity as a case study.

Autor: Anthony Tony Cox L; Cox Associates, 503 Franklin St., Denver, CO, 80218, USA. Electronic address: tcoxdenver@aol.com., Popken DA; Cox Associates, 503 Franklin St., Denver, CO, 80218, USA., Kaplan AM; A. Michael Kaplan & Associates, LLC, 23 Wilkinson Drive, Landenberg, PA, 19350, USA. Electronic address: amkaplan1@comcast.net., Plunkett LM; Integrative Biostrategies LLC, 1127 Eldridge Parkway, Suite 300-335, Houston, TX, 77077, USA. Electronic address: lmplunkett@inbiostrat.com., Becker RA; American Chemistry Council, 700 Second Street NE, Washington, D.C. 20002, USA. Electronic address: Rick_Becker@americanchemistry.com.

Publikováno v: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2016 Jun; Vol. 77, pp. 54-64. Date of Electronic Publication: 2016 Feb 13.