Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anthony T. Trinh"'
Autor:
Justin E. Richards, Ken Koerner, Richard D. Betzold, Caroline S. Schlee, Thomas E. Grissom, Rosemary A. Kozar, Benjamin T Fedeles, Jonathan J. Morrison, Jonathan H. Chow, Thomas M. Scalea, Anthony T Trinh, Corinne Renner
Publikováno v:
Shock. 55:55-60
BACKGROUND Tranexamic acid (TXA) administration is recommended in severely injured trauma patients. We examined TXA administration, admission fibrinolysis phenotypes, and clinical outcomes following traumatic injury and hypothesized that TXA was asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd498f31873cb74efd09613c1df183a8
https://doi.org/10.1097/shk.0000000000001608
https://doi.org/10.1097/shk.0000000000001608
Autor:
Thomas M. Scalea, Michael A. Mazzeffi, Benjamin T Fedeles, Kenichi A. Tanaka, Jonathan J. Morrison, Corinne Renner, Anthony T Trinh, Jonathan H. Chow, Peter Rock, Justin E. Richards, Caroline S. Schlee
Publikováno v:
Journal of the American College of Surgeons. 230:798-808
Background Coagulopathy is common in multitrauma patients and repletion of procoagulant factor deficiency with fresh frozen plasma (FFP) improves hemostasis. Optimal kaolin-thromboelastography thresholds for FFP transfusion in trauma patients have no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2192b05d276a85c58c5fae3b7ae7dbf
https://doi.org/10.1016/j.jamcollsurg.2020.01.033
https://doi.org/10.1016/j.jamcollsurg.2020.01.033
Autor:
Anthony T. Trinh, Michele Campaigne Larsen, Pierre R. Bushel, Colin R. Jefcoate, Randal S. Tibbetts, Sang Hwa Kim, Adam S. Mastrocola
Publikováno v:
Nucleic Acids Research
cAMP response element binding protein (CREB) is a key regulator of glucose metabolism and synaptic plasticity that is canonically regulated through recruitment of transcriptional coactivators. Here we show that phosphorylation of CREB on a conserved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7847472c3259340b82ce71acf9ae2edb
http://europepmc.org/articles/PMC5175338
http://europepmc.org/articles/PMC5175338
Publikováno v:
Journal of Biological Chemistry. 288:24731-24741
The list of factors that participate in the DNA damage response to maintain genomic stability has expanded significantly to include a role for proteins involved in RNA processing. Here, we provide evidence that the RNA-binding protein fused in sarcom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6954bd23184cceba23ed8b3a8fb95962
https://doi.org/10.1074/jbc.m113.497974
https://doi.org/10.1074/jbc.m113.497974
Autor:
Gerald E. Dodson, Anthony T. Trinh, Yuling Shi, Naval P. Shanware, Partha S. Mukhopadhyay, Randal S. Tibbetts
Publikováno v:
Journal of Biological Chemistry. 282:9236-9243
The functionally related ATM (ataxia telangiectasia-mutated) and ATR (ATM-Rad3-related) protein kinases are critical regulators of DNA damage responses in mammalian cells. ATM and ATR share highly overlapping substrate specificities and show a strong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a939c51270df7da6585ab07bd2bde19
https://doi.org/10.1074/jbc.m609256200
https://doi.org/10.1074/jbc.m609256200
Publikováno v:
Journal of Biological Chemistry. 282:6283-6291
The cyclic AMP-response element-binding protein (CREB) is a bZIP family transcription factor implicated as an oncoprotein and neuron survival factor. CREB is activated in response to cellular stimuli, including cAMP and Ca(2+), via phosphorylation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3002ba41d00df508f060f333d15831a7
https://doi.org/10.1074/jbc.m610674200
https://doi.org/10.1074/jbc.m610674200
The cyclic AMP response element-binding protein (CREB) initiates transcriptional responses to a wide variety of stimuli. CREB activation involves its phosphorylation on Ser-133, which promotes interaction between the CREB kinase-inducible domain (KID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e10729661ba4885a0ffbea1f96bab6
https://europepmc.org/articles/PMC3745323/
https://europepmc.org/articles/PMC3745323/
Autor:
David A. Wassarman, Gerald E. Dodson, Rebeccah J. Katzenberger, Stacey A. Rimkus, Anthony T. Trinh, Randal S. Tibbetts
Publikováno v:
Genesdevelopment. 22(9)
Mutations in ATM (Ataxia telangiectasia mutated) result in Ataxia telangiectasia (A-T), a disorder characterized by progressive neurodegeneration. Despite advances in understanding how ATM signals cell cycle arrest, DNA repair, and apoptosis in respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a2f3d93fcb2864c922651e79408eed
https://pubmed.ncbi.nlm.nih.gov/18408079
https://pubmed.ncbi.nlm.nih.gov/18408079
Publikováno v:
Cell cycle (Georgetown, Tex.). 4(11)
Hydroxyurea (HU) is a competitive inhibitor of ribonucleotide reductase that is used for the treatment of myeloproliferative disorders. HU inhibits DNA replication and induces apoptosis in a cell type-dependent manner, yet the relevant pathways that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6441a6b2cb53965788e739eb4aa63352
https://pubmed.ncbi.nlm.nih.gov/16258278
https://pubmed.ncbi.nlm.nih.gov/16258278