Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Anthony T. Tan"'
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 101995- (2023)
Summary: Specialized T cells are located in the nasal cavity and act as the first line of defense against respiratory viral infection. Here, we present a protocol for the detection and characterization of antigen-specific nasal-resident T cells. We d
Externí odkaz:
https://doaj.org/article/547fed37c3ae4f2d8173e7e0d15c0165
Autor:
Megan Schwarz, Slim Mzoughi, Daniel Lozano-Ojalvo, Anthony T. Tan, Antonio Bertoletti, Ernesto Guccione
Publikováno v:
Current Research in Immunology, Vol 3, Iss , Pp 215-221 (2022)
As vaccine deployment improves the healthcare emergency status caused by the SARS-CoV-2 pandemic, we need reliable tools to evaluate the duration of protective immunity at a global scale. Seminal studies have demonstrated that while neutralizing anti
Externí odkaz:
https://doaj.org/article/d8349f6fc609413d9e0f99d8a9c69ee5
Autor:
Katie Healy, Andrea Pavesi, Tiphaine Parrot, Michał J. Sobkowiak, Susanne E. Reinsbach, Haleh Davanian, Anthony T. Tan, Soo Aleman, Johan K. Sandberg, Antonio Bertoletti, Margaret Sällberg Chen
Publikováno v:
JHEP Reports, Vol 3, Iss 4, Pp 100318- (2021)
Background & Aims: Virus-specific T cell dysfunction is a common feature of HBV-related hepatocellular carcinoma (HBV-HCC). Conventional T (ConT) cells can be redirected towards viral antigens in HBV-HCC when they express an HBV-specific receptor; ho
Externí odkaz:
https://doaj.org/article/1ca0a3c213a64d5897fe3f31b9de4c40
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10679 (2022)
The emergence of new SARS-CoV-2 lineages able to escape antibodies elicited by infection or vaccination based on the Spike protein of the Wuhan isolates has reduced the ability of Spike-specific antibodies to protect previously infected or vaccinated
Externí odkaz:
https://doaj.org/article/b3b8ca1e01f54c2aba3dfe16d4677d84
Autor:
Anthony T. Tan, Martin Linster, Chee Wah Tan, Nina Le Bert, Wan Ni Chia, Kamini Kunasegaran, Yan Zhuang, Christine Y.L. Tham, Adeline Chia, Gavin J.D. Smith, Barnaby Young, Shirin Kalimuddin, Jenny G.H. Low, David Lye, Lin-Fa Wang, Antonio Bertoletti
Publikováno v:
Cell Reports, Vol 34, Iss 6, Pp 108728- (2021)
Summary: Virus-specific humoral and cellular immunity act synergistically to protect the host from viral infection. We interrogate the dynamic changes of virological and immunological parameters in 12 patients with symptomatic acute SARS-CoV-2 infect
Externí odkaz:
https://doaj.org/article/c8f64ca8ef0343c9be0d502c42de65fd
Autor:
Christine Y.L. Tham, Janine Kah, Anthony T. Tan, Tassilo Volz, Adeline Chia, Katja Giersch, Yvonne Ladiges, Alessandro Loglio, Marta Borghi, Camille Sureau, Pietro Lampertico, Marc Lütgehetmann, Maura Dandri, Antonio Bertoletti
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 4, Pp 100060- (2020)
Summary: Hepatitis delta virus (HDV) requires hepatitis B virus (HBV) to complete its infection cycle and causes severe hepatitis, with limited therapeutic options. To determine the prospect of T cell therapy in HBV/HDV co-infection, we study the imp
Externí odkaz:
https://doaj.org/article/6d4ddfe9419f438f9c91e9142a2b1cb6
Publikováno v:
Viruses, Vol 1, Iss 2, Pp 91-103 (2009)
The successful control of HBV infection requires an efficient expansion of distinct elements of the adaptive immune system (B cells, helper and cytotoxic T cells) that, due to the hepatotropic nature of HBV, need to operate in the liver parenchyma. I
Externí odkaz:
https://doaj.org/article/bc6e0726403547829a40bbf0814e8d6e
Autor:
Anthony T. Tan, Wai Lu-En, Junliang Fu, Antonio Bertoletti, Ming Shi, Jinfang Zhao, Sarene Koh, Yuanyuan Li, Fanping Meng, Chun-Bao Zhou, Shuang-jie Yu, Limin Liu, Juan Wu, Yunbo Xie, Ji-Yuan Zhang, Tingting Wang, Siyu Wang, Junqing Luan, Fu-Sheng Wang, Lei Shi, Yingjuan Shen, Regina Wanju Wong, Jiehua Jin, Wei Hu
Publikováno v:
Hepatology International
Background & aims Immunotherapy with hepatitis B virus (HBV)-specific TCR redirected T (HBV-TCR-T) cells in HBV-related hepatocellular carcinoma (HBV-HCC) patients after liver transplantation was reported to be safe and had potential therapeutic effi
Publikováno v:
Cellular and Molecular Immunology
During viral infections, antibodies and T cells act together to prevent pathogen spread and remove virus-infected cells. Virus-specific adaptive immunity can, however, also trigger pathological processes characterized by localized or systemic inflamm
Publikováno v:
Virologica Sinica. 37(6)