Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anthony T. Dobson"'
Publikováno v:
Journal of Virology. 68:7148-7158
The ability to direct foreign gene expression from the herpes simplex virus type 1 (HSV-1) genome during an acute or latent infection is a subject of increasing importance in the utilization of HSV vectors for gene therapy. Little is known about the
Publikováno v:
Virology. 189:150-160
Pathways of viral gene expression were investigated during the acute phase of sensory ganglionic infection with HSV-1. To facilitate these studies we constructed KOS/62-3, an HSV-1 vector in which the Escherichia coli lac-Z gene was inserted behind b
Publikováno v:
American journal of obstetrics and gynecology. 179(2)
OBJECTIVE: Acyclovir is an antiviral agent that inhibits acute herpes simplex virus replication and decreases the frequency of reactivation, but it is not currently used to prevent primary disease or the establishment of latency. The purpose of this
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 88(3)
The latency-associated transcript (LAT) is the major viral transcript detected by in situ hybridization of mouse and human sensory ganglia latently infected with herpes simplex virus type 1. The last 750 bases of LAT are complementary to infected-cel
Publikováno v:
Intervirology. 32(5)
A clinical isolate, designated 145, of herpes simplex virus (HSV) had type 1 characteristics as determined by monoclonal antibody immunofluorescence, heat stability of viral thymidine kinase (TK), BamHI restriction endonuclease pattern, and absence o
Publikováno v:
Neuron. 5(3)
A genetically engineered herpes simplex virus variant was constructed for use as a stable gene vector for neurons. To inhibit replication, the agent possessed a deletion in the immediate early gene ICP4, and to minimize reactivation from the latent s
Autor:
Anthony T. Dobson, Marcelle I. Cedars, Shehua Shen, Victor Y. Fujimoto, Mitchell P. Rosen, Tracy L Telles
Publikováno v:
Fertility and Sterility. 80:8
Publikováno v:
Fertility and Sterility. 78:S76
Autor:
E. K. Wagner, Farhad Sederati, Anthony T. Dobson, W. M. Flanagan, Michael Farrell, Lawrence T. Feldman, Jack G. Stevens, Gayathri Devi-Rao
Publikováno v:
Journal of virology. 63(9)
The herpes simplex virus type 1 latency-associated transcript (LAT) is expressed as a major species in latently infected mouse neurons. Previous sequence analysis revealed no obvious promoter elements near the 5' end of the LAT, but a TATA box and ot