Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Anthony Stea"'
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 308:805-813
Pyrethroids are commonly used insecticides for both household and agricultural applications. It is generally reported that voltage-gated sodium channels are the primary target for toxicity of these chemicals to humans. The phylogenetic and structural
Autor:
Anthony Stea, Kathy G. Sutton, Francisco S. Cayabyab, Janette Mezeyova, Terrance P. Snutch, Celia M. Santi, David Parker, John E. McRory, Kevin S. Hamming
Publikováno v:
The Journal of Neuroscience. 22:396-403
T-type calcium channels play critical roles in cellular excitability and have been implicated in the pathogenesis of a variety of neurological disorders including epilepsy. Although there have been reports that certain neuroleptics that primarily tar
Publikováno v:
Annals of the New York Academy of Sciences. 868:118-130
N-type calcium channels both generate the initial calcium signal to trigger neurotransmitter release and also interact with synaptic release proteins at many mammalian central nervous system synapses. Two isoforms of the alpha 1B N-type channel from
Autor:
Michael K. Ahlijanian, Heck Steven D, Anthony Stea, Gerald W. Zamponi, Chet Siok, Robert A. Volkmann, Terry P. Snutch, Kathy G. Sutton
Publikováno v:
Molecular Pharmacology. 54:407-418
Peptide toxins have proved to be useful agents, both in discriminating between different components of native calcium channel currents and in the molecular isolation and designation of their cloned channel counterparts. Here, we describe the isolatio
Publikováno v:
Proceedings of the National Academy of Sciences. 93:1486-1491
The modulation of a family of cloned neuronal calcium channels by stimulation of a coexpressed mu opioid receptor was studied by transient expression in Xenopus oocytes. Activation of the morphine receptor with the synthetic enkephalin [D-Ala2,N-Me-P
Publikováno v:
Neuron. 15:929-940
The modulation of Ca2+ channel activity by protein kinases contributes to the dynamic regulation of neuronal physiology. Using the transient expression of a family of neuronal Ca2+ channels, we have identified several factors that contribute to the P
Autor:
Steven R. Vincent, Stefan J. Dubel, Emmanuel Bourinet, W J Tomlinson, Tuck Wah Soong, Terry P. Snutch, Anthony Stea
Publikováno v:
Proceedings of the National Academy of Sciences. 91:10576-10580
Functional expression of the rat brain alpha 1A Ca channel was obtained by nuclear injection of an expression plasmid into Xenopus oocytes. The alpha 1A Ca current activated quickly, inactivated slowly, and showed a voltage dependence typical of high
Autor:
Steven R. Vincent, Tuck Wah Soong, Stefan J. Dubel, Anthony Stea, Connie D. Hodson, Terry P. Snutch
Publikováno v:
Science. 260:1133-1136
Oscillatory firing patterns are an intrinsic property of some neurons and have an important function in information processing. In some cells, low voltage-activated calcium channels have been proposed to underlie a depolarizing potential that regulat
Autor:
Anthony Stea, Terrance P. Snutch
Publisher Summary This chapter presents molecular and functional insights into voltage-gated calcium (Ca) channels. Ca channels are not only found ubiquitously in nervous, neuroendocrine, and muscle tissues, but are also found in endocrine, epithelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ec6c6cdfa39e7fccbea4418d8253e61
https://doi.org/10.1016/s1569-2558(03)32016-8
https://doi.org/10.1016/s1569-2558(03)32016-8
Autor:
Anthony Stea, David L. Baillie, Terrance P. Snutch, Kevin S. Hamming, Janette Mezeyova, John E. McRory, Kathy G. Sutton, Celia M. Santi
Publikováno v:
The Journal of biological chemistry. 276(6)
Voltage-gated calcium channels represent a heterogenous family of calcium-selective channels that can be distinguished by their molecular, electrophysiological, and pharmacological characteristics. We report here the molecular cloning and functional