Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anthony Slavin"'
Autor:
Edward Htun van der Horst, Brendon T. Frank, Lawrence Chinn, Angela Coxon, Shyun Li, Fanny Polesso, Anthony Slavin, Astrid Ruefli-Brasse, Holger Wesche
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 4, Pp 340-346 (2008)
Midkine (MDK) is a heparin-binding growth factor involved in growth, survival, migration, and differentiation of various target cells and dysregulation of MDK signaling is implicated in a variety of inflammatory diseases and cancers. Although MDK has
Externí odkaz:
https://doaj.org/article/536b22dbcd454592b9a9dd88e9acc18f
Autor:
Min Hu, Ryan Duggan, Eric R. Goedken, Heath A. McDonald, Peter F. Slivka, J. Wetter, Marc H Domanus, Anthony Slavin, Sujatha M. Gopalakrishnan, Victoria E. Scott, Marian Namovic, Namjin Chung, Erin Murphy, John Locklear, Chen-Lin Hsieh, Charles Lu, Steven D. Pratt, Alex Lipovsky, Rebecca M. Edelmayer, Jacob King, Diana Donnelly-Roberts
Publikováno v:
ACS Chemical Biology. 14:857-872
Interleukin-17A (IL17A) plays a critical role in the development of numerous autoimmune diseases, including psoriasis. The clinical success of IL17A neutralizing biologics in psoriasis has underlined its importance as a drug discovery target. While m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e412ff837e5c673b8f22c55b9a72b01
https://doi.org/10.1021/acschembio.8b00260
https://doi.org/10.1021/acschembio.8b00260
Autor:
Jeffrey Sullivan, Crystal Brown, Michele Mayo, Vaishali Dixit, Bradley Enerson, Haojing Rong, Bin Yang, Chris De Savi, Jared Gollob, Nello Mainolfi, Anthony Slavin, Cedric Hubeau
Publikováno v:
The Journal of Immunology. 208:60.07-60.07
Signal transducer and activator of transcription 3 (STAT3), an “undruggable” transcription factor activated by a variety of receptor- and non-receptor tyrosine kinases, plays a critical role in activation pathways triggered by cytokines, hormones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33cf0b326918837caa79bf3794ddacc4
https://doi.org/10.4049/jimmunol.208.supp.60.07
https://doi.org/10.4049/jimmunol.208.supp.60.07
Autor:
Jesus Paez-Cortez, Paul G. Thomas, Song Baik, David Price, Karsten Hokamp, Sarah C. Edwards, Bruno Silva-Santos, Rachel M. McLoughlin, Stephen J. Lalor, Valerie Pivorunas, Caroline E. Sutton, Graham Anderson, Walid Awad, Barry Moran, Julie C. Ribot, James E. McLaren, Aoife M. McGinley, Anthony Slavin, Fiona M. Roche, Pradyot Dash, Kristin Ladell, Nopporn Apiwattanakul, Kingston H. G. Mills, Michael Macoritto, Kelly L. Miners, Lori Dowding, Emma J. Grant
Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine
Journal of Experimental Medicine
T cells classically express either αβ or γδ T cell receptors. We have identified T cells that express both pairs of receptors. These hybrid αβ-γδ T cells exhibit a hyperinflammatory and migratory phenotype and act as first responders in infec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b959b0b0d180f391caec4c75edeeac7c
https://doi.org/10.1084/jem.20190834
https://doi.org/10.1084/jem.20190834
Autor:
Cedric J Hubeau, Veronica Campbell, Albert Lee, Emily Lurier, Stephanie Skouras, Michele Mayo, Michael Fitzgerald, Amy Wang, Dapeng Chen, Haojing Rong, Xiaozhang Zheng, Richard Chesworth, Jared Gollob, Nello Mainolfi, Anthony Slavin
Publikováno v:
The Journal of Immunology. 206:66.16-66.16
Interleukin-1 receptor associated kinase 4 (IRAK4) plays a critical role in TLR and IL-1R mediated inflammation through its catalytic and scaffolding functions, making it an attractive target for the treatment of immune-inflammatory diseases. Kymera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::956f346e192dadb51eddebf014413541
https://doi.org/10.4049/jimmunol.206.supp.66.16
https://doi.org/10.4049/jimmunol.206.supp.66.16
Autor:
Alfredo Csibi, Nello Mainolfi, Veronica Campbell, Bin Yang, Mike Sintchak, Michele Mayo, Sharon Townson, Sean Zhu, Haojing Rong, Hari Kamadurai, Henry Li, Phillip Liu, Anthony Slavin, Karen Yuan, Scott F. Rusin, Kirti Sharma, Chris De Savi, Nan Ji, Jared Gollob, Yogesh Chutake, Duncan Walker, Alice McDonald
Publikováno v:
Cancer Research. 80:LB-088
Signal transducer and activator of transcription 3 (STAT3) has been implicated in multiple aspects of tumorigenesis. In addition to increasing cancer cell proliferation and survival, constitutively activated STAT3 is proposed to regulate cross-talk b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf55692bc7b3ca0baadf1d0b2f5d6458
https://doi.org/10.1158/1538-7445.am2020-lb-088
https://doi.org/10.1158/1538-7445.am2020-lb-088
Autor:
Anthony Slavin, Annette J. Schwartz Sterman, Regina Mario, Kristen Legendre, Yingli Yang, Susan V. Westmoreland, Karin Orsi, Robert Dunstan, Sonia Terrillon, Rajesh V. Kamath, Tariq Ghayur, Martha Mayo, Heather Knight, Sarah Wilson, Terry Melim
Publikováno v:
Gastroenterology. 156:S-493
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48a2291a9eed365b7a3a342f49608231
https://doi.org/10.1016/s0016-5085(19)38098-9
https://doi.org/10.1016/s0016-5085(19)38098-9
Autor:
Sam Karsen, Liang Zhang, Jamie Erickson, Anthony Slavin, Annette J. Schwartz Sterman, Gricelda H. Simler, Rajesh V. Kamath, Craig Wallace, Stephen Laroux, Ruoqi Peng, Stephanie M. Gaudette, Bradford L. McRae, Soumya Mitra, Christopher Stedman, Marc-André Wurbel, Christine M. Nelson
Publikováno v:
Gastroenterology. 156:S-698
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::731400959da9dcf2926a1d01039d803f
https://doi.org/10.1016/s0016-5085(19)38672-x
https://doi.org/10.1016/s0016-5085(19)38672-x
Autor:
Jamie Erickson, Robert Dunstan, Marc-André Wurbel, Ruoqi Peng, Anthony Slavin, Rajesh V. Kamath, Annette Schwartz Sterman
Publikováno v:
Gastroenterology. 154:S-1364
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ed597e2e4b8764428dfce1853a29364
https://doi.org/10.1016/s0016-5085(18)34458-5
https://doi.org/10.1016/s0016-5085(18)34458-5
Autor:
Michael Eckart, Bo Liu, Masao Yamada, Jennifer L. Harris, Weijia Ou, Anthony Slavin, Mary S. Turner, Elizabeth Zuo, Feng Gao, Tove Tuntland, Alana Althage, Tomohisa Ogawa, John Trauger, Ka Fai Suen
Publikováno v:
Protein expression and purification. 71(1)
Transient transfection of mammalian cells in suspension culture has recently emerged as a very useful method for production of research-scale quantities of recombinant proteins. The most commonly used cell lines for this purpose are suspension-adapte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341cbca456571c928dae793964376ec5
https://pubmed.ncbi.nlm.nih.gov/20045465
https://pubmed.ncbi.nlm.nih.gov/20045465