Zobrazeno 1 - 10 of 35 pro vyhledávání: '"Anthony Simmons"'
2
Use of a lentivirus/VSV pseudotype virus for highly efficient genetic redirection of human peripheral blood lymphocytes
Autor: Kristina Jantz, Anthony Simmons
Publikováno v: Nature Protocols. 1:2688-2700
Genetic redirection of lymphocytes that have been engineered to recognize antigens other than those originally programmed by their rearranged germlines is a potentially powerful immunotherapeutic tool. The rationale for the protocol described here is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d01c94ceb09115f261830b612cb1f30
https://doi.org/10.1038/nprot.2006.409
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3
Use of mRNA differential display to study the action of lymphocyte subsets in vivo and application to a murine model of herpes simplex virus infection
Autor: Anthony Simmons, Ray Wilkinson, David C. Tscharke
Publikováno v: Immunology Letters. 74:127-132
Depletion of lymphocyte subsets in vivo using monoclonal antibodies against cell surface markers has helped to define the roles for these subsets in many immune processes. However, in some cases the mechanisms through which these lymphocytes act rema
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6e5e45412f6032f57a1fc2a2050fa9
https://doi.org/10.1016/s0165-2478(00)00239-x
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4
Molecular localisation of a G-protein mRNA using differential display and in situ hybridization
Autor: Ray Wilkinson, Anthony Simmons, David C. Tscharke
Publikováno v: Brain Research Protocols. 5:290-297
Defining molecular repertoires within virally infected tissues of the nervous system may provide insight into the pathogenesis of, and immunity to, neurotropic viruses. Here we report the application of such a method, namely mRNA differential display
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65dda6434f19e57efc9f7f16e411454f
https://doi.org/10.1016/s1385-299x(00)00025-8
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6
Cell Surface Expression of H2 Antigens on Primary Sensory Neurons in Response to Acute but Not Latent Herpes Simplex Virus Infection In Vivo
Autor: Rosemarie A. Pereira, Anthony Simmons
Publikováno v: Journal of Virology. 73:6484-6489
Herpes simplex virus (HSV) infection has high community impact as a result of the high prevalence of genital herpes and its ability to cause life-threatening infections in immunocompromised hosts and sporadic cases of rapidly fatal encephalitis (35).
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a3b216704e781e7b40ecc12338f1f4
https://doi.org/10.1128/jvi.73.8.6484-6489.1999
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7
Concatemeric Intermediates of Equine Herpesvirus Type 1 DNA Replication Contain Frequent Inversions of Adjacent Long Segments of the Viral Genome
Autor: Anthony Simmons, Barry Slobedman
Publikováno v: Virology. 229:415-420
In common with other α-herpesviruses, the genome of equine herpesvirus type-1 (EHV-1) comprises covalently linked long and short unique sequences of DNA, each flanked by inverted repeats. Equimolar amounts of two genomic isomers, generated by free i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea59a60b337c5e338aedd1a2d9f5a0e
https://doi.org/10.1006/viro.1997.8447
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8
Quantitative analysis of herpes simplex virus DNA and transcriptional activity in ganglia of mice latently infected with wild-type and thymidine kinase-deficient viral strains
Autor: Barry Slobedman, Anthony Simmons, Stacey Efstathiou
Publikováno v: Journal of General Virology. 75:2469-2474
The relationship between herpes simplex virus (HSV) DNA replication and establishment of latent infection was examined using an experimental model that makes use of the segmental sensory innervation of mouse flanks (T7 to T12). Ganglia from consecuti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef058f5b5f1750211b38b701eb8a4a88
https://doi.org/10.1099/0022-1317-75-9-2469
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9
Upregulation of class I major histocompatibility complex gene expression in primary sensory neurons, satellite cells, and Schwann cells of mice in response to acute but not latent herpes simplex virus infection in vivo
Autor: Anthony Simmons, R A Pereira, D C Tscharke
Publikováno v: The Journal of Experimental Medicine
Major histocompatibility complex (MHC) deficiency is typical of almost all resident cells in normal neural tissue. However, CD8+ T cells, which recognize antigenic peptides in the context of class I MHC molecules, are known to mediate clearance of he
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74af6736245fad18244ee14befa3102e
http://europepmc.org/articles/PMC2191654
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10
Intranuclear foci containing low abundance herpes simplex virus latency-associated transcripts visualized by non-isotopic in situ hybridization
Autor: Stacey Efstathiou, Jane Arthur, Anthony Simmons
Publikováno v: Journal of General Virology. 74:1363-1370
During latent infection of neurons with herpes simplex virus type 1 (HSV-1), several RNA transcripts of varying abundance arise from a single locus within the virus repeats. The functions of latency-associated transcripts (LATs) are unknown and the r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd908f1b639756e8758d9cbe0c466ee
https://doi.org/10.1099/0022-1317-74-7-1363
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