Zobrazeno 1 - 10
of 970
pro vyhledávání: '"Anthony S Fauci"'
Autor:
Sinmanus Vimonpatranon, Livia R Goes, Amanda Chan, Isabella Licavoli, Jordan McMurry, Samuel R Wertz, Anush Arakelyan, Dawei Huang, Andrew Jiang, Cindy Huang, Joyce Zhou, Jason Yolitz, Alexandre Girard, Donald Van Ryk, Danlan Wei, Il Young Hwang, Craig Martens, Kishore Kanakabandi, Kimmo Virtaneva, Stacy Ricklefs, Benjamin P Darwitz, Marcelo A Soares, Kovit Pattanapanyasat, Anthony S Fauci, James Arthos, Claudia Cicala
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011209 (2023)
CD4+ tissue resident memory T cells (TRMs) are implicated in the formation of persistent HIV reservoirs that are established during the very early stages of infection. The tissue-specific factors that direct T cells to establish tissue residency are
Externí odkaz:
https://doaj.org/article/dbbfe6462eef488fb4eecaebbb698732
Autor:
Giulia Calenda, Ines Frank, Géraldine Arrode-Brusés, Amarendra Pegu, Keyun Wang, James Arthos, Claudia Cicala, Kenneth A Rogers, Lisa Shirreff, Brooke Grasperge, James L Blanchard, Stephanie Maldonado, Kevin Roberts, Agegnehu Gettie, Francois Villinger, Anthony S Fauci, John R Mascola, Elena Martinelli
Publikováno v:
PLoS Pathogens, Vol 15, Iss 5, p e1007776 (2019)
VRC01 protects macaques from vaginal SHIV infection after a single high-dose challenge. Infusion of a simianized anti-α4β7 mAb (Rh-α4β7) just prior to, and during repeated vaginal exposures to SIVmac251 partially protected macaques from vaginal S
Externí odkaz:
https://doaj.org/article/56f99e9871a14c77a113d5c201dca31e
Autor:
Sakaorat Lertjuthaporn, Claudia Cicala, Donald Van Ryk, Matthew Liu, Jason Yolitz, Danlan Wei, Fatima Nawaz, Allison Doyle, Brooke Horowitch, Chung Park, Shan Lu, Yang Lou, Shixia Wang, Ruimin Pan, Xunqing Jiang, Francois Villinger, Siddappa N Byrareddy, Philip J Santangelo, Lynn Morris, Constantinos Kurt Wibmer, Kristin Biris, Rosemarie D Mason, Jason Gorman, Joseph Hiatt, Elena Martinelli, Mario Roederer, Dai Fujikawa, Giacomo Gorini, Genoveffa Franchini, Anush Arakelyan, Aftab A Ansari, Kovit Pattanapanyasat, Xiang-Peng Kong, Anthony S Fauci, James Arthos
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007278 (2018)
The GI tract is preferentially targeted during acute/early HIV-1 infection. Consequent damage to the gut plays a central role in HIV pathogenesis. The basis for preferential targeting of gut tissues is not well defined. Recombinant proteins and synth
Externí odkaz:
https://doaj.org/article/1d27a974a42f4d20a2e0217100ce0387
Autor:
David M Morens, Anthony S Fauci
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003467 (2013)
Externí odkaz:
https://doaj.org/article/08cb2e31635b40489d05cb0fd668d351
Autor:
Christina Guzzo, Jamie Fox, Yin Lin, Huiyi Miao, Raffaello Cimbro, Brian F Volkman, Anthony S Fauci, Paolo Lusso
Publikováno v:
PLoS Pathogens, Vol 9, Iss 12, p e1003852 (2013)
CD8+ T cells play a key role in the in vivo control of HIV-1 replication via their cytolytic activity as well as their ability to secrete non-lytic soluble suppressive factors. Although the chemokines that naturally bind CCR5 (CCL3/MIP-1α, CCL4/MIP-
Externí odkaz:
https://doaj.org/article/d7b2e8d43d7643fe956871c5d5bd67d6
Autor:
Lia Vassena, Huiyi Miao, Raffaello Cimbro, Mauro S Malnati, Giulia Cassina, Michael A Proschan, Vanessa M Hirsch, Bernard A Lafont, Michel Morre, Anthony S Fauci, Paolo Lusso
Publikováno v:
PLoS Pathogens, Vol 8, Iss 4, p e1002636 (2012)
Although treatment with interleukin-7 (IL-7) was shown to transiently expand the naïve and memory T-cell pools in patients with chronic HIV-1 infection receiving antiretroviral therapy (ART), it is uncertain whether a full immunologic reconstitution
Externí odkaz:
https://doaj.org/article/fc41a4b83dfa4464b5b0238448aa17e4
Autor:
Fatima Nawaz, Claudia Cicala, Donald Van Ryk, Katharine E Block, Katija Jelicic, Jonathan P McNally, Olajumoke Ogundare, Massimiliano Pascuccio, Nikita Patel, Danlan Wei, Anthony S Fauci, James Arthos
Publikováno v:
PLoS Pathogens, Vol 7, Iss 2, p e1001301 (2011)
Mucosal transmission of HIV is inefficient. The virus must breach physical barriers before it infects mucosal CD4+ T cells. Low-level viral replication occurs initially in mucosal CD4+ T cells, but within days high-level replication occurs in Peyer's
Externí odkaz:
https://doaj.org/article/8784641fb4874ee6932b21860cd590a8
Autor:
Steven J Reynolds, Cissy Kityo, Claire W Hallahan, Geoffrey Kabuye, Diana Atwiine, Frank Mbamanya, Francis Ssali, Robin Dewar, Marybeth Daucher, Richard T Davey, Peter Mugyenyi, Anthony S Fauci, Thomas C Quinn, Mark R Dybul
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10307 (2010)
Short cycle treatment interruption could reduce toxicity and drug costs and contribute to further expansion of antiretroviral therapy (ART) programs.A 72 week, non-inferiority trial enrolled one hundred forty six HIV positive persons receiving ART (C
Externí odkaz:
https://doaj.org/article/e9266d96ceae4c009bf03922e0c95b03
Autor:
Manuela Fogli, Domenico Mavilio, Enrico Brunetta, Stefania Varchetta, Khaled Ata, Gregg Roby, Colin Kovacs, Dean Follmann, Daniela Pende, Jeffrey Ward, Edward Barker, Emanuela Marcenaro, Alessandro Moretta, Anthony S Fauci
Publikováno v:
PLoS Pathogens, Vol 4, Iss 7, p e1000101 (2008)
Understanding the cellular mechanisms that ensure an appropriate innate immune response against viral pathogens is an important challenge of biomedical research. In vitro studies have shown that natural killer (NK) cells purified from healthy donors
Externí odkaz:
https://doaj.org/article/1f55587d873f4ba0a4c9e4e30c216973
Autor:
Jennifer Hartt Meyers, J Shawn Justement, Claire W Hallahan, Eric T Blair, Yongming A Sun, M Angeline O'Shea, Gregg Roby, Shyam Kottilil, Susan Moir, Colin M Kovacs, Tae-Wook Chun, Anthony S Fauci
Publikováno v:
PLoS ONE, Vol 2, Iss 5, p e458 (2007)
Plasmacytoid dendritic cells (pDCs) are important mediators of innate immunity that act mainly through secretion of interferon (IFN)-alpha. Previous studies have found that these cells can suppress HIV in vitro; additionally, pDCs have been shown to
Externí odkaz:
https://doaj.org/article/d44c8696110246179f9b5da77b358390