Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Anthony S, Fargnoli"'
Autor:
Alejandro Orlowski, Michael G. Katz, Sarah M. Gubara, Anthony S. Fargnoli, Kenneth M. Fish, Thomas Weber
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 16, Iss , Pp 192-203 (2020)
Gene therapy with adeno-associated virus (AAV)-based vectors shows great promise for the gene therapeutic treatment of a broad array of diseases. In fact, the treatment of genetic diseases with AAV vectors is currently the only in vivo gene therapy a
Externí odkaz:
https://doaj.org/article/15ad95b43f0f4dd189705de14587d1d1
Autor:
Jason C. Kovacic, Mohammad Tofael Kabir Sharkar, Yoav Hadas, Roger J. Hajjar, Ann Anu Kurian, Hanna Girard, Seonghun Yoon, Asharee Mahmood, Maria Paola Santini, Dalila Pinto, Djamel Lebeche, Vadim Chepurko, Nishat Sultana, Toshiro Io, Keerat Kaur, Shahin Rafii, Lior Zangi, Anthony S. Fargnoli, Jimeen Yoo, Ajit Magadum, Rinat Komargodski, Elena Chepurko, Efrat Eliyahu, Magdalena M. Żak
Publikováno v:
Molecular Therapy. 29:3042-3058
Reprogramming non-cardiomyocytes (non-CMs) into cardiomyocyte (CM)-like cells is a promising strategy for cardiac regeneration in conditions such as ischemic heart disease. Here, we used a modified mRNA (modRNA) gene delivery platform to deliver a co
Autor:
Tyler C Lewis, Deane E. Smith, Anthony S. Fargnoli, Nader Moazami, Stacey Chen, Zachary N. Kon, Aubrey C. Galloway
Publikováno v:
Seminars in Thoracic and Cardiovascular Surgery. 33:407-415
Thoracic organs from hepatitis C virus (HCV) positive donors are not commonly used for transplantation. The development of direct-acting antivirals (DAA) for HCV treatment has led to renewed interest in using HCV-positive organs. We evaluated HCV tra
Autor:
Michael G. Katz, Anthony S. Fargnoli, Sarah M. Gubara, Kenneth Fish, Thomas Weber, Charles R. Bridges, Roger J. Hajjar, Kiyotake Ishikawa
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 6, Iss 1, p 8 (2019)
Advances in DNA- and RNA-based technologies have made gene therapy suitable for many lung diseases, especially those that are hereditary. The main objective of gene therapy is to deliver an adequate amount of gene construct to the intended target cel
Externí odkaz:
https://doaj.org/article/eba4073123d04bceba63aab9a23938bf
Autor:
Zachary Kon, Nader Moazami, Jochen G. Raimann, Alex Reyentovich, S. Rao, Deane E. Smith, Tyler C Lewis, J. Pavone, Anthony S. Fargnoli, Navneet Narula, T. Saraon, Claudia Gidea, Maxine Stachel, Andre L. Moreira, Hannah Karpe
Publikováno v:
The Journal of Heart and Lung Transplantation. 39:1199-1207
Increased utilization of hepatitis C virus (HCV)-positive donors has increased transplantation rates. However, high levels of viremia have been documented in recipients of viremic donors. There is a knowledge gap in how transient viremia may impact a
Autor:
Anthony S. Fargnoli, Jonathan A Cohen, Sophia Madjarova, Sarah M. Gubara, Hylton P Gordon, Michael G. Katz, Virginia L. Gillespie, Shahood Fazal
Publikováno v:
Comp Med
Ischemic myocardial disease is a major cause of death among humans worldwide; it results in scarring and pallor of the myocardium and triggers an inflammatory response that contributes to impaired left ventricular function. This response includes and
Autor:
Stephanie H. Chang, Stacey Chen, Julius A. Carillo, Aubrey C. Galloway, Marjan Alimi, Anthony S. Fargnoli, Nader Moazami, Travis C. Geraci, Zachary N. Kon, Harvey I. Pass, Deane E. Smith
Publikováno v:
Journal of Cardiac Surgery
Background and aim of the study: Patients with severe coronavirus disease 2019 (COVID-19) develop a profound cytokine-mediated pro-inflammatory response. This study reports outcomes in 10 patients with COVID-19 supported on veno-venous extracorporeal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c3ba44b6bf2ed1c579968c6995dc04
https://doi.org/10.22541/au.161888021.17404769/v1
https://doi.org/10.22541/au.161888021.17404769/v1
Autor:
Michael G. Katz, Anthony S. Fargnoli, Charles R. Bridges, Roger J. Hajjar, Sarah M. Gubara, Elena Chepurko
Publikováno v:
Heart Fail Rev
Rodent surgical animal models of heart failure (HF) are critically important for understanding the proof of principle of the cellular alterations underlying the development of the disease as well as evaluating therapeutics. Robust, reproducible roden
Autor:
Anthony S. Fargnoli, T. Saraon, B. Kadosh, Nader Moazami, S. Rao, Claudia Gidea, J. Pavone, Deane E. Smith, R. Goldberg, Alex Reyentovich, Zachary N. Kon, A. Emmarco
Publikováno v:
The Journal of Heart and Lung Transplantation. 40:S423-S424
Purpose The Lavare Cycle (LC) is a pre-programmed speed modulation algorithm in the HVAD device designed to automatically increase both ventricular and pump washing. The ReVOLVE trial suggested a reduction in adverse outcomes including stroke. We ass
Autor:
Yassine Sassi, Benjamin Strauss, Marine Cacheux, Joseph G. Akar, Emerson Obus, Anthony S. Fargnoli, Lahouaria Hadri, Michael G. Katz, Fadi G. Akar, Malik Bisserier, James P. Hummel
Publikováno v:
Heart Rhythm
Background Electrophysiological (EP) properties have been studied mainly in the monocrotaline model of pulmonary arterial hypertension (PAH). Findings are confounded by major extrapulmonary toxicities, which preclude the ability to draw definitive co