Výsledky vyhledávání - "Anthony Raffo"

Akademický článek

Gene Therapy with p14/tBID Induces Selective and Synergistic Apoptosis in Mutant Ras and Mutant p53 Cancer Cells In Vitro and In Vivo

Autor: Robert L. Fine, Yuehua Mao, Dario Garcia-Carracedo, Gloria H. Su, Wanglong Qiu, Uri Hochfeld, Gwen Nichols, Yong-Liang Li, Richard D. Dinnen, Anthony Raffo, Paul W. Brandt-Rauf

Publikováno v: Biomedicines, Vol 11, Iss 2, p 258 (2023)

Any gene therapy for cancer will be predicated upon its selectivity against cancer cells and non-toxicity to normal cells. Therefore, safeguards are needed to prevent its activation in normal cells. We designed a minimal p14ARF promoter with upstream

Externí odkaz: https://doaj.org/article/63ac97b61c3745b18f46b4184dca843e

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Akademický článek

C-Terminal p53 Palindromic Tetrapeptide Restores Full Apoptotic Function to Mutant p53 Cancer Cells In Vitro and In Vivo

Autor: Robert L. Fine, Yuehua Mao, Richard Dinnen, Ramon V. Rosal, Anthony Raffo, Uri Hochfeld, Patrick Senatus, Jeffrey N. Bruce, Gwen Nichols, Hsin Wang, Yongliang Li, Paul W. Brandt-Rauf

Publikováno v: Biomedicines, Vol 11, Iss 1, p 137 (2023)

We previously demonstrated that a synthetic monomer peptide derived from the C-terminus of p53 (aa 361–382) induced preferential apoptosis in mutant p53 malignant cells, but not normal cells. The major problem with the peptide was its short half-li

Externí odkaz: https://doaj.org/article/90a0fac39c5d4ce1a697f6695fbb8e57

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A Study of the Effect of Energy Healing on In Vitro Tumor Cell Proliferation

Autor: Anthony Raffo, Sonal Shah, Alfred T. Ogden, Christian M. Pettker, Mehmet C. Oz, Silviu Itescu

Publikováno v: The Journal of Alternative and Complementary Medicine. 5:359-365

This study examined the effect of energy healing on in vitro tumor cell growth using the cell culture model similar to that embraced by oncologists to assess the effect of chemotherapeutic agents. After selecting an energy healer based on his ability

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34f1e4624ef9a34f4404a4286252d67
https://doi.org/10.1089/acm.1999.5.359

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Chemosensitization of bladder carcinoma cells by bcl-xL antisense oligonucleotides

Autor: IRINA LEBEDEVA, ANTHONY RAFFO, ROBERT RANDO, JOSHUA OJWANG, PAUL COSSUM, C. A. STEIN

Publikováno v: The Journal of urology. 166(2)

We investigated antisense inhibition of anti-apoptotic bcl-xL and bcl-2 proteins to increase chemosensitization in the T24 and 5637 bladder carcinoma cell lines.A T24 bladder carcinoma cell line stably over expressing bcl-xL protein was constructed.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688c68be31ee7e46bedb0f7482d45148
https://pubmed.ncbi.nlm.nih.gov/11458048

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Akademický článek

Role of vesicular monoamine transporter type 2 in rodent insulin secretion and glucose metabolism revealed by its specific antagonist tetrabenazine.

Autor: Anthony Raffo

Publikováno v: Journal of Endocrinology; Jul2008, Vol. 198 Issue 1, p41-49, 9p

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The capacity of chondrocytes to respond to serum is enhanced by organ culture in the absence of serum, stimulated by serum, and modified by ascorbate

Autor: Anthony Raffo, Stuart Jaffe, Paul D. Benya

Publikováno v: Archives of Biochemistry and Biophysics. 232:323-336

Cartilage slices maintained in organ culture have been shown to develop an enhanced capacity to respond to serum. The response was measured at the initiation of culture and after 3 and 7 days of culture in medium containing an inhibitor of DNA synthe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91be71b11b0aefda30e4b02e3cbebe9d
https://doi.org/10.1016/0003-9861(84)90548-4

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