Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Anthony R. M. Coates"'
Autor:
Alexander Liu, Robert Hammond, Kenneth Chan, Chukwugozie Chukwuenweniwe, Rebecca Johnson, Duaa Khair, Eleanor Duck, Oluwaseun Olubodun, Kristian Barwick, Winston Banya, James Stirrup, Peter D. Donnelly, Juan Carlos Kaski, Anthony R. M. Coates
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2819 (2023)
Introduction: The ferritin–lymphocyte ratio (FLR) is a novel inflammatory biomarker for the assessment of acute COVID-19 patients. However, the prognostic value of FLR for predicting adverse clinical outcomes in COVID-19 remains unclear, which hind
Externí odkaz:
https://doaj.org/article/9aeef0c6d76a4c4bb7c75d2c6cc3e20a
Autor:
Alexander Liu, Robert Hammond, Kenneth Chan, Chukwugozie Chukwuenweniwe, Rebecca Johnson, Duaa Khair, Eleanor Duck, Oluwaseun Olubodun, Kristian Barwick, Winston Banya, James Stirrup, Peter D. Donnelly, Juan Carlos Kaski, Anthony R. M. Coates
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2423 (2023)
Background: CRB-65 (Confusion; Respiratory rate ≥ 30/min; Blood pressure ≤ 90/60 mmHg; age ≥ 65 years) is a risk score for prognosticating patients with COVID-19 pneumonia. However, a significant proportion of COVID-19 patients have normal ches
Externí odkaz:
https://doaj.org/article/dacec034922740b6b498f8609afadd25
Autor:
Alexander Liu, Robert Hammond, Kenneth Chan, Chukwugozie Chukwuenweniwe, Rebecca Johnson, Duaa Khair, Eleanor Duck, Oluwaseun Olubodun, Kristian Barwick, Winston Banya, James Stirrup, Peter D. Donnelly, Juan Carlos Kaski, Anthony R. M. Coates
Introduction Assessment of inpatient mortality risk in COVID-19 patients is important for guiding clinical decision-making. High sensitivity cardiac troponin T (hs-cTnT) is a biomarker of cardiac injury associated with a worse prognosis in COVID-19.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e997c0db4991d17b38e3b01e49c82ec2
https://hdl.handle.net/10023/27473
https://hdl.handle.net/10023/27473
Autor:
Anthony R. M. Coates
All cellular life-forms can exist in replicating and non-replicating states. Organisms replicate only when the conditions are beneficial, and when not replicating they concentrate on survival of these environmental stresses. Many bacteria, harmful to
Autor:
Alexander Liu, Robert Hammond, Kenneth Chan, Chukwugozie Chukwuenweniwe, Rebecca Johnson, Duaa Khair, Eleanor Duck, Oluwaseun Olubodun, Kristian Barwick, Winston Banya, James Stirrup, Peter D. Donnelly, Juan Carlos Kaski, Anthony R. M. Coates
Publikováno v:
Journal of Personalized Medicine; Volume 13; Issue 6; Pages: 909
Background : In COVID-19 patients, lymphocyte–CRP ratio (LCR) is a promising biomarker for predicting adverse clinical outcomes. How well LCR performs compared to conventional inflammatory markers for prognosticating COVID-19 patients remains uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b613f52a118d50ecf2af70b4878894e4
https://doi.org/10.3390/jpm13060909
https://doi.org/10.3390/jpm13060909
Autor:
Yanmin Hu, Anthony R M Coates
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20958 (2011)
Mycobacterium tuberculosis dosRS two-component regulatory system controls transcription of approximately 50 genes including hspX, acg and Rv2030c, in response to hypoxia and nitric oxide conditions and within macrophages and mice. The hspX lies betwe
Externí odkaz:
https://doaj.org/article/a49c7d2e14c64a8a8757b009be14493e
Autor:
Yanmin Hu, Anthony R M Coates
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5150 (2009)
The macrophage is the natural niche of Mycobacterium tuberculosis infection. In order to combat oxidative and nitrosative stresses and persist in macrophages successfully, M. tuberculosis is endowed with a very efficient antioxidant complex. Amongst
Externí odkaz:
https://doaj.org/article/1f670ef48fbc42889eebe79b49b73076
Autor:
Alireza Shamaei-Tousi, Francesco D'Aiuto, Luigi Nibali, Andrew Steptoe, Anthony R M Coates, Mohamed Parkar, Nikos Donos, Brian Henderson
Publikováno v:
PLoS ONE, Vol 2, Iss 11, p e1198 (2007)
Evidence is emerging that molecular chaperones, in addition to their intracellular protein folding actions, can act as intercellular signaling proteins with an ability to modulate leukocyte function. Recent evidence has also shown that these proteins
Externí odkaz:
https://doaj.org/article/8624a1fcefc945309b2f043bb0931a10
Autor:
Anthony R M, Coates, Gerry, Halls
Publikováno v:
Handbook of experimental pharmacology. (211)
There are 19 compounds in late-stage clinical trials, of which ten may be suitable for Gram-positive infections. However, there are only five compounds in development for Gram-negative infections, in addition to four broad-spectrum ones. There are tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dd3948949a2354be8b1e6558e7edcf4b
https://pubmed.ncbi.nlm.nih.gov/23090602
https://pubmed.ncbi.nlm.nih.gov/23090602
Publikováno v:
Novartis Foundation symposium. 291
Eukaryotic and prokaryotic chaperonin 60s (Cpn60s) activate macrophages to produce pro-inflammatory cytokines. CD14 and TLR4 have been proposed as potential Cpn receptors. In addition, Cpn60s can block LPS-induced activation. This is a dose-related e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2eb264bf8a5ef2ca6485027dc63a71db
https://pubmed.ncbi.nlm.nih.gov/18575272
https://pubmed.ncbi.nlm.nih.gov/18575272