Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anthony R. DiSanto"'
Publikováno v:
Clinical Pharmacology in Drug Development. 3:493-498
Treating children with compounded liquid formulations of tablets intended for adults, where quality-control and compliance issues exist, was previously the only antihypertensive therapy option. A 1-mg/mL oral solution of enalapril maleate (enalapril)
Autor:
Anthony R. DiSanto, Gil Golden
Publikováno v:
Clinical Drug Investigation. 29:539-549
Food has reportedly not affected the systemic bioavailability of the atypical antipsychotic drug clozapine. However, searches of the medical literature could find no studies to support this food claim for any formulation of clozapine. The purpose of
Autor:
Jeffrey S. Barrett, Lee J. McDonald, Esther M. Morris, Anthony R. DiSanto, John Darnow, Shashank Rohatagi
Publikováno v:
Pharmaceutical Research. 14:50-55
Purpose. A Selegiline Transdermal System (STS) is under development for indications which may not be optimally or safely treated with oral selegiline. Studies were conducted to evaluate the in vitro penetration and skin metabolism of selegiline in or
Publikováno v:
Clinical pharmacology in drug development. 3(6)
Treating children with compounded liquid formulations of tablets intended for adults, where quality-control and compliance issues exist, was previously the only antihypertensive therapy option. A 1-mg/mL oral solution of enalapril maleate (enalapril)
Autor:
Shashank Rohatagi, Jeffrey S. Barrett, Richard J. Morales, Kimberly E. DeWitt, Anthony R. DiSanto
Publikováno v:
American Journal of Therapeutics. 3:298-313
The pharmacokinetics of oral selegiline hydrochloride were examined in two crossover studies in healthy volunteers: a 5-mg b.i.d. administration in the fed-versus-fasted state and a 5-mg b.i.d. versus 10-mg q.d. multiple-dose administration. Food inc
Autor:
Anthony R. DiSanto, Jeffrey S. Barrett, Sara K. Watson, Thomas J. Hochadel, Richard J. Morales, Kimberly E. DeWitt, Shashank Rohatagi
Publikováno v:
American journal of therapeutics. 3(10)
This open-label, two-phase cross-over study compared the safety and pharmacokinetics of transdermally administered selegiline and orally administered selegiline hydrochloride in elderly men and women (n = 6/gender). Single oral doses of 10 mg selegil
Autor:
John G. Wagner, Anthony R. Disanto
Publikováno v:
Journal of Pharmaceutical Sciences. 61:1090-1094
Plasma concentrations following rapid intravenous injection of 2-, 5-, 7.5-, 10-, and 15-mg./kg. doses of methylene blue in a dog were obtained. The single-dose data were fit to both a nonlinear heterogeneous one-compartment open model with binding t
Autor:
John G. Wagner, Anthony R. Disanto
Publikováno v:
Journal of Pharmaceutical Sciences. 58:1077-1085
Turnover time (T) of goldfish in 2-8% v/v ethanol-water (C) was determined in two crossover studies: (a) three body weight groups of six fish each, and (b) six larger fish. Each fish had different treatment schedule. Analyses of variance of log T sho
Autor:
Anthony R. Disanto, John G. Wagner
Publikováno v:
Journal of Pharmaceutical Sciences. 61:1086-1090
Methylene blue was administered orally to seven normal human subjects at a dose of 10 mg. in capsule form. Total urinary recovery ranged from 53 to 97% of the dose, with an average of 74%. Of the material recovered, an average of 78% was excreted as
Publikováno v:
Archives of surgery (Chicago, Ill. : 1960). 112(12)
• Serial serum and fecal erythromycin concentrations were measured in a group of ten healthy volunteers following oral intake of 3 gm of neomycin sulfate and 3 gm of erythromycin base over a ten-hour period, as is currently used in preoperative int