Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Anthony Possemato"'
Autor:
Lauren Foltz, Nagashree Avabhrath, Jean-Marc Lanchy, Tyler Levy, Anthony Possemato, Majd Ariss, Bradley Peterson, Mark Grimes
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109585- (2024)
Summary: Knowledge of cell signaling pathways that drive human neural crest differentiation into craniofacial chondrocytes is incomplete, yet essential for using stem cells to regenerate craniomaxillofacial structures. To accelerate translational pro
Externí odkaz:
https://doaj.org/article/23015d337b934de4b9abaaaf6113fc78
Autor:
Jennifer S. Carew, Allison Berger, Michael Thomas, Stephen Blakemore, Michael Milhollen, Sean A. Beausoleil, Anthony Possemato, Claudia M. Espitia, Peter G. Smith, Kevin R. Kelly, Steffan T. Nawrocki
PDF file - 1755K, Supplemental Figure 1: Effects of targeted p65 knockdown on cisplatin sensitivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627036159925f122bbe6cee401c9efba
https://doi.org/10.1158/1078-0432.22451391
https://doi.org/10.1158/1078-0432.22451391
Autor:
Jennifer S. Carew, Allison Berger, Michael Thomas, Stephen Blakemore, Michael Milhollen, Sean A. Beausoleil, Anthony Possemato, Claudia M. Espitia, Peter G. Smith, Kevin R. Kelly, Steffan T. Nawrocki
PDF file - 71K, Supplemental Table 1. Proteins Altered >2-fold by Treatment with MLN4924.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0b67ed86626b6eb94f1ada6e5c926e
https://doi.org/10.1158/1078-0432.22451385
https://doi.org/10.1158/1078-0432.22451385
Autor:
Jennifer S. Carew, Allison Berger, Michael Thomas, Stephen Blakemore, Michael Milhollen, Sean A. Beausoleil, Anthony Possemato, Claudia M. Espitia, Peter G. Smith, Kevin R. Kelly, Steffan T. Nawrocki
PDF file - 3554K, Supplemental Figure 2: Effects of caspase inhibition and antioxidant treatment on MLN4924/cisplatin-induced DNA damage.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a0198af11e49361783b5d136b4d01d
https://doi.org/10.1158/1078-0432.22451388
https://doi.org/10.1158/1078-0432.22451388
Autor:
Jennifer S. Carew, Allison Berger, Michael Thomas, Stephen Blakemore, Michael Milhollen, Sean A. Beausoleil, Anthony Possemato, Claudia M. Espitia, Peter G. Smith, Kevin R. Kelly, Steffan T. Nawrocki
Purpose: Ovarian cancer has the highest mortality rate of all female reproductive malignancies. Drug resistance is a major cause of treatment failure and novel therapeutic strategies are urgently needed. MLN4924 is a NEDDylation inhibitor currently u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cbb66a754615a2340af9aba36490809
https://doi.org/10.1158/1078-0432.c.6522186.v1
https://doi.org/10.1158/1078-0432.c.6522186.v1
Severe birth defects or major injuries to the face require surgical reconstruction and rehabilitation. The ability to make bona fide craniofacial cartilage – cartilage of the head and face – from patient-derived induced pluripotent stem cells (iP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::725334e5c986fcea1a4b0ac246410153
https://doi.org/10.1101/2021.05.31.446459
https://doi.org/10.1101/2021.05.31.446459
Publikováno v:
Targeted Protein Degradation ISBN: 9781071616642
Protein degradation is a critical component of all facets of cell biology, and recently methods have been developed to make use of targeted protein degradation as both an investigative tool and a potential therapeutic avenue. Mass spectrometry-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c23f0000d08893c85a9756d47a2bbef9
https://doi.org/10.1007/978-1-0716-1665-9_16
https://doi.org/10.1007/978-1-0716-1665-9_16
SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2
Autor:
Shankara Anand, Lewis C. Cantley, Long He, Joseph D. Trimarco, Benjamin E. Nilsson-Payant, Edward R. Kastenhuber, Harel Weinstein, Andrew D. Davidson, Maia Kavanagh-Williamson, Elena Piskounova, Anthony Possemato, Tyler Levy, Cait E. Hamele, Xinyu Zhu, Robert E. Schwartz, Benjamin R. tenOever, Kaitlyn N. Burke, John Blenis, Jared L. Johnson, Gina Lee, Kripa Shobana-Ganesh, François Aguet, Sasha Tkachev, Gad Getz, David A. Matthews, Clare M. Smith, Kate J. Heesom, Nicholas S. Heaton, Purushothama Rao Tata, Shuibing Chen, Danielle K. Bulaon, Aleksandra Tata, Ryan R. Chaparian, Peter Hornbeck, Alexander Kerelsky, Katarina M. Liberatore, Tomer M. Yaron, Brook E. Heaton, Marisa N. Mercadante, Benjamin M. Cohen, Alfred T. Harding, Olivier Elemento, Sean A. Beausoleil, Ting-Yu Lin, Tristan X. Jordan
Publikováno v:
bioRxiv
While vaccines are vital for preventing COVID-19 infections, it is critical to develop new therapies to treat patients who become infected. Pharmacological targeting of a host factor required for viral replication can suppress viral spread with a low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8def4c82dbd399ebda8cd6b0c2c056c
https://europepmc.org/articles/PMC7430567/
https://europepmc.org/articles/PMC7430567/
Autor:
Joao A. Paulo, Sean A. Beausoleil, Daniel Mulhern, Steven P. Gygi, Ailan Guo, Anthony Possemato
Publikováno v:
Journal of Proteome Research. 16:1506-1514
A comprehensive view of protein phosphorylation remains an unmet challenge in the field of cell biology. Mass spectrometry-based proteomics is one of the most promising approaches for identifying thousands of phosphorylation events in a single experi
Autor:
Mohammad J. Eslamizade, Albert Quintana, Elisenda Sanz, Karim Nader, Anthony Possemato, Matthew P. Stokes, Pavel V. Baranov, Randal J. Kaufman, Adonis Yiannakas, Maya Lalzar, Kathryn Abell, Vinh Tai Truong, Abdessattar Khlaifia, Mauro Costa-Mattioli, Shunit Gal-Ben-Ari, Arkady Khoutorsky, Azam Asgarihafshejani, Noah Cohen, Rapita Sood, Nahum Sonenberg, Vijendra Sharma, Peng Wang, Jean-Claude Lacaille, Alissa J. Nelson, Tzu-Yu Hung, Stephen J Kiniry, Fatemeh Saffarzadeh, A. Claudio Cuello, Danning Lou, Kobi Rosenblum
Publikováno v:
Signal Transduction and Targeted Therapy
An important tenet of learning and memory is the notion of a molecular switch that promotes the formation of long-term memory1–4. The regulation of proteostasis is a critical and rate-limiting step in the consolidation of new memories5–10. One of