Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Anthony P. H. Wright"'
Autor:
Laia Sadeghi, Anthony P. H. Wright
Publikováno v:
Cells, Vol 12, Iss 15, p 2010 (2023)
Multiple signaling pathways facilitate the survival and drug resistance of malignant B-cells by regulating their migration and adhesion to microenvironmental niches. NF-κB pathways are commonly dysregulated in mantle cell lymphoma (MCL), but the exa
Externí odkaz:
https://doaj.org/article/2676e7f2696241219e2d7a0091f7d8c7
Autor:
Yaxuan, Liu, Olga, Axell, Tom, van Leeuwen, Robert, Konrat, Pedram, Kharaziha, Catharina, Larsson, Anthony P H, Wright, Svetlana, Bajalica-Lagercrantz
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6345, p 6345 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 12
International Journal of Molecular Sciences
Volume 22
Issue 12
Rare germline pathogenic TP53 missense variants often predispose to a wide spectrum of tumors characterized by Li-Fraumeni syndrome (LFS) but a subset of variants is also seen in families with exclusively hereditary breast cancer (HBC) outcomes. We h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e6c8b8abfb50481247d91cd8a0e00e1b
https://www.mdpi.com/1422-0067/22/12/6345
https://www.mdpi.com/1422-0067/22/12/6345
Autor:
Xinyuan Liu, Rainer Heuchel, Jianping Liu, Anthony P. H. Wright, Gustav Arvidsson, Matthias Löhr, Beate Gündel, Xidan Li
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 7, Pp 101107-(2021)
Translational Oncology, Vol 14, Iss 7, Pp 101107-(2021)
Highlights • We described a straightforward and highly reproducible 3D culturing method to investigate the intercellular crosstalk between pancreatic cancer and pancreatic stellate cells (PSCs)/cancer associated fibroblasts (CAFs). • Pancreatic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309016806d03c6c70de0bb89b2ca621a
https://pubmed.ncbi.nlm.nih.gov/33946033
https://pubmed.ncbi.nlm.nih.gov/33946033
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75057 (2013)
Mammalian Myc proteins are important determinants of cell proliferation as well as the undifferentiated state of stem cells and their activity is frequently deregulated in cancer. Based mainly on conservation in the C-terminal DNA-binding and dimeriz
Externí odkaz:
https://doaj.org/article/88e922e39649407cbbbd6f184558c054
The transcription factor MYC regulates the expression of a vast number of genes and is implicated in various human malignancies, for which it’s deregulation by genomic events such as translocation or amplification can be either disease-defining or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89314690ba0c723bc64f8f7a148b8638
https://doi.org/10.1101/2020.07.13.200238
https://doi.org/10.1101/2020.07.13.200238
Autor:
Laia Sadeghi, Anthony P. H. Wright, Gustav Arvidsson, Magali Merrien, André Görgens, Birgitta Sander, C. I. Edvard Smith, Agata M. Wasik
Publikováno v:
Cancers
Cancers, Vol 12, Iss 1143, p 1143 (2020)
Cancers, Vol 12, Iss 1143, p 1143 (2020)
Interactions between lymphoma cells and stromal cells play a key role in promoting tumor survival and development of drug resistance. We identified differences in key signaling pathways between the JeKo-1 and REC-1 mantle cell lymphoma (MCL) cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e0b9d6f3c1d09877eb8f8396fae60b
https://doi.org/10.1101/2020.03.06.980235
https://doi.org/10.1101/2020.03.06.980235
Autor:
Alf Grandien, Agata M. Wasik, Birgitta Sander, Birger Christensson, Gustav Arvidsson, Martin Lord, Anthony P. H. Wright
Publikováno v:
Haematologica. 103:e594-e597
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29b826865d1ec7a7474a122382b297a3
https://doi.org/10.3324/haematol.2018.197467
https://doi.org/10.3324/haematol.2018.197467
Autor:
Evdokiya Salamanova, Lennart Nilsson, Do-Hyoung Kim, Joana Costeira-Paulo, Anthony P. H. Wright, Kyou-Hoon Han
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1862:1452-1461
Background Adaptive mutations that alter protein functionality are enriched within intrinsically disordered protein regions (IDRs), thus conformational flexibility correlates with evolvability. Pre-structured motifs (PreSMos) with transient propensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72555150b538f90c7fd9ccf011cb5e2
https://doi.org/10.1016/j.bbagen.2018.03.015
https://doi.org/10.1016/j.bbagen.2018.03.015
Publikováno v:
Haematologica
A subset of hematologic cancer patients is refractory to treatment or suffers relapse, due in part to minimal residual disease, whereby some cancer cells survive treatment. Cell-adhesion-mediated drug resistance is an important mechanism, whereby can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766110a1947dc0f09f90c41f3e054bc1
https://doi.org/10.3324/haematol.2017.182048
https://doi.org/10.3324/haematol.2017.182048
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11009 (2010)
We have previously demonstrated that subsets of Ssn6/Tup target genes have distinct requirements for the Schizosaccharomyces pombe homologs of the Tup1/Groucho/TLE co-repressor proteins, Tup11 and Tup12. The very high level of divergence in the histo
Externí odkaz:
https://doaj.org/article/13775ddddbc84be88370700d37afb58d