Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Anthony P. Albino"'
Autor:
Christoph Heuck, John D. Shaughnessy, Bart Barlogie, Anthony P. Albino, Pingping Qu, Sarah K. Johnson, Qing Zhang
Publikováno v:
International Journal of Hematology. 94:321-333
Despite improvement in therapeutic efficacy, multiple myeloma (MM) remains incurable with a median survival of approximately 10 years. Gene-expression profiling (GEP) can be used to elucidate the molecular basis for resistance to chemotherapy through
Publikováno v:
Cell Cycle. 9:2170-2176
Cigarette smoke (CS) is the major cause of lung cancer and contributes to the development of other malignancies. Attempts have been made to construct reduced toxicity cigarettes, presumed to have diminished genotoxic potential. One such product on th
Autor:
Gene Gillman, Frank Traganos, T. Jeffrey Clark, Patrick Rainey, Anthony P. Albino, Ellen D. Jorgensen, Hong Zhao, Zbigniew Darzynkiewicz, Diana Gietl
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 678:43-52
Differentiation among American cigarettes relies primarily on the use of proprietary tobacco blends, menthol, tobacco substitutes, paper porosity, paper additives, and filter ventilation. These characteristics substantially alter per cigarette yields
Autor:
R. Patrick Rainey, Tianrong Cheng, Diana Gietl, Anthony P. Albino, Andy Stinson, Xuling Shi, I. Gene Gillman
Publikováno v:
Toxicology Mechanisms and Methods. 19:401-409
Oxidative stress in biological systems can result in radical-induced lipid peroxidation (LPO), which can lead to the production of secondary reactive by-products such as 4-hydroxy-2-nonenal (HNE), malondialdehyde (MDA), acrolein, and acetaldehyde. Th
Publikováno v:
Molecular Medicine. 15:268-274
The ability to quit smoking successfully displays substantial heritability in classical and molecular genetic studies. Twin studies suggest that some of the genetics for the ability to quit overlap with genetic components of nicotine dependence, but
Autor:
Anthony P. Albino
Publikováno v:
Pigment Cell Research. 3:199-218
Publikováno v:
Nicotine & Tobacco Research. 10:1139-1148
A randomized double-blind, active controlled, parallel group, multi-center phase II clinical trial was conducted to evaluate the efficacy of reduced-nicotine cigarettes as a novel smoking cessation treatment (under Investigational Device Exemption 69
Autor:
Toshiki Tanaka, Wei Dai, Anthony P. Albino, Hong Zhao, H. Dorota Halicka, Frank Traganos, Xuan Huang, Zbigniew Darzynkiewicz
Publikováno v:
Cytometry Part A. :648-661
This review covers the topic of cytometric assessment of activation of Ataxia telangiectasia mutated (ATM) protein kinase and histone H2AX phosphorylation on Ser139 in response to DNA damage, particularly the damage that involves formation of DNA dou
Autor:
Anthony P, Gulati, Yang-Ming, Yang, David, Harter, Asok, Mukhopadhyay, Bharat B, Aggarwal, Bharat A, Aggarwal, Deborah L, Benzil, John, Whysner, Anthony P, Albino, Raj, Murali, Meena, Jhanwar-Uniyal
Publikováno v:
Molecular Carcinogenesis. 45:26-37
The roles of the mitogen-activated kinase protein (MAPK) pathway, nuclear factor-kappa B (NF-κB), and activator protein-1 (AP-1) in cellular responses to growth factors and mitogen are well established. However, the manner by which these proliferati
Global Gene Expression Analysis of Human Bronchial Epithelial Cells Treated with Tobacco Condensates
Publikováno v:
Cell Cycle. 3:1152-1166
Gene expression patterns were assessed in normal human bronchial epithelial (NHBE) cells exposed to cigarette smoke condensates (CSC) from commercial cigarettes in order to develop a better understanding of the genomic impact of tobacco exposure, and