Výsledky vyhledávání - "Anthony P Albert"

Akademický článek

Hormone-stimulated modulation of endocytic trafficking in osteoclasts

Autor: Gudrun eStenbeck, Kevin M Lawrence, Anthony P Albert

Publikováno v: Frontiers in Endocrinology, Vol 3 (2012)

A precise control of vesicular trafficking is crucial not only for osteoclastic bone resorption, but also for the crosstalk between osteoclasts and osteoblasts, which regulates bone homeostasis. In addition to the release of growth factors and modula

Externí odkaz: https://doaj.org/article/c8d4de03679d4ee2ba4a7f033a8da765

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Akademický článek

Stimulation of the calcium‐sensing receptor induces relaxations through CGRP and NK1 receptor‐mediated pathways in male rat mesenteric arteries

Autor: Simonette R. E. Carlton‐Carew, Harry Z. E. Greenberg, Iain A. Greenwood, Anthony P. Albert

Publikováno v: Physiological Reports, Vol 12, Iss 12, Pp n/a-n/a (2024)

Abstract Stimulation of the calcium‐sensing receptor (CaSR) regulates vascular contractility, but cellular mechanisms involved remain unclear. This study investigated the role of perivascular sensory nerves in CaSR‐induced relaxations of male rat

Externí odkaz: https://doaj.org/article/34c84558b7e340b2a30044c6527452af

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Akademický článek

Differential FSH Glycosylation Modulates FSHR Oligomerization and Subsequent cAMP Signaling

Autor: Uchechukwu T. Agwuegbo, Emily Colley, Anthony P. Albert, Viktor Y. Butnev, George R. Bousfield, Kim C. Jonas

Publikováno v: Frontiers in Endocrinology, Vol 12 (2021)

Follicle-stimulating hormone (FSH) and its target G protein-coupled receptor (FSHR) are essential for reproduction. Recent studies have established that the hypo-glycosylated pituitary FSH glycoform (FSH21/18), is more bioactive in vitro and in vivo

Externí odkaz: https://doaj.org/article/0be72419f62b4829957f4e9975955289

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Marked oestrous cycle-dependent regulation of rat arterial KV7.4 channels driven by GPER1

Autor: Samuel N. Baldwin, Elizabeth A. Forrester, Natalie Z. M. Homer, Ruth Andrew, Vincenzo Barrese, Jennifer B. Stott, Brant E. Isakson, Anthony P. Albert, Iain A. Greenwood

Publikováno v: Baldwin, S N, Forrester, E A, Homer, N Z M, Andrew, R, Barrese, V, Stott, J B, Isakson, B E, Albert, A P & Greenwood, I A 2022, ' Marked oestrous cycle-dependent regulation of rat arterial KV7.4 channels driven by GPER1 ', British Journal of Pharmacology . https://doi.org/10.1111/bph.15947

Background and purposeKcnq-encoded KV7 channels (termed KV7.1-5) regulate vascular smooth muscle cell (VSMC) contractility at rest and as downstream targets of receptor mediated responses. However, the current literature focuses predominantly on male

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e0759f0cd9255b04c25a24fb956c0a
https://www.pure.ed.ac.uk/ws/files/313271074/British_J_Pharmacology_2022_Baldwin_Marked_oestrous_cycle_dependent_regulation_of_rat_arterial_KV7_4_channels_driven.pdf

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Marked oestrous cycle-dependent regulation of rat arterial K

Autor: Samuel N, Baldwin, Elizabeth A, Forrester, Natalie Z M, Homer, Ruth, Andrew, Vincenzo, Barrese, Jennifer B, Stott, Brant E, Isakson, Anthony P, Albert, Iain A, Greenwood

Publikováno v: British journal of pharmacologyREFERENCES.

Kcnq-encoded KRT-qPCR, immunocytochemistry, proximity ligation assay and wire myography were performed in renal and mesenteric arteries. Circulating sex hormone concentrations were determined by liquid chromatography-tandem mass spectrometry. Whole-c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::78a9a1461ae21d9714d146660e14053f
https://pubmed.ncbi.nlm.nih.gov/36085551

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Obligatory role for PKCδ in PIP 2 ‐mediated activation of store‐operated TRPC1 channels in vascular smooth muscle cells

Autor: William A. Large, Anthony P. Albert, Miguel Martín-Aragón Baudel, Jian Shi

Publikováno v: The Journal of Physiology. 598:3911-3925

Key points In vascular smooth muscle cells (VSMCs), activation of Ca2+ -permeable store-operated channels (SOCs) composed of canonical transient receptor potential channel 1 (TRPC1) subunits mediate Ca2+ entry pathways which regulate contraction, pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91944b6109e0d6ccc37e64901b1331b8
https://doi.org/10.1113/jp279947

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Obligatory role for PKCδ in PIP

Autor: Miguel A S, Martín-Aragón Baudel, Jian, Shi, William A, Large, Anthony P, Albert

Publikováno v: The Journal of physiology. 598(18)

In vascular smooth muscle cells (VSMCs), activation of CaIn vascular smooth muscle cells (VMSCs), stimulation of Ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ae9afe41e65a600670689244024e9e22
https://pubmed.ncbi.nlm.nih.gov/33080052

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Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced nitric oxide production and vasorelaxation in rabbit mesenteric arteries

Autor: Harry Z.E. Greenberg, Kazi S. Jahan, Anthony P. Albert, Alexander Zargaran, W-S Vanessa Ho, Dhanak M Khan, Simonette R E Carlton-Carew

Publikováno v: Vascular Pharmacology

Stimulation of calcium-sensing receptors (CaSR) by increasing the external calcium concentration (Ca2 +]o) induces endothelium-dependent vasorelaxation through nitric oxide (NO) production and activation of intermediate Ca2 +-activated K+ currents (I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809723402bae15fc244e85278aff9484
https://doi.org/10.1016/j.vph.2017.08.005

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MARCKS mediates vascular contractility through regulating interactions between voltage-gated Ca2+ channels and PIP2

Autor: Harry Z.E. Greenberg, Miguel Martín-Aragón Baudel, Vincenzo Barrese, Iain A. Greenwood, Kazi S. Jahan, Sam Khavandi, Jian Shi, Anthony P. Albert

Publikováno v: Vascular Pharmacology
Jahan, K S, Shi, J, Greenberg, H Z E, Khavandi, S, Baudel, MM-A, Barrese, V, Greenwood, I A & Albert, A P 2020, ' MARCKS mediates vascular contractility through regulating interactions between voltage-gated Ca2+ channels and PIP2 ', Vascular Pharmacology . https://doi.org/10.1016/j.vph.2020.106776

Phosphatidylinositol 4,5-bisphosphate (PIP2) acts as substrate and unmodified ligand for Gq-protein-coupled receptor signalling in vascular smooth muscle cells (VSMCs) that is central for initiating contractility. The present work investigated how PI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af39a0baec6600a1546fdabd04263c12
http://europepmc.org/articles/PMC7549404

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Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced relaxations and nitric oxide production in mesenteric arteries: comparative study using wild-type and TRPC1-/- mice

Autor: Kazi S. Jahan, Anthony P. Albert, Alexander Zargaran, Lutz Birnbaumer, Simonette R E Carlton-Carew, Harry Z.E. Greenberg

Publikováno v: Channels. 2019, 13(1)
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
Channels
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Fil: Greenberg, Harry Z. E. University of London. Vascular Biology Research Centre, Molecular & Clinical Sciences Research Institute; Inglaterra Fil: Carlton Carew, Simonette R. E. University of London. Vascular Biology Research Centre, Molecular & C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0b9e55d65fcab7f8c4bbd1b5d073d2e
https://repositorio.uca.edu.ar/handle/123456789/9807

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