Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Anthony Owens"'
Autor:
Danielle O. Sambo, Min Lin, Anthony Owens, Joseph J. Lebowitz, Ben Richardson, Darin A. Jagnarine, Madhur Shetty, Meghan Rodriquez, Taiwo Alonge, Mishaal Ali, Jonathan Katz, Long Yan, Marcelo Febo, L. Keith Henry, Adriaan W. Bruijnzeel, Lynette Daws, Habibeh Khoshbouei
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
The dopamine transporter (DAT), a regulator of dopamine homeostasis in the brain, and sigma-1 receptor (σ1R), an endoplasmic reticulum membrane protein, are both implicated in drug addiction. In this work, the authors investigate how σ1R modulates
Externí odkaz:
https://doaj.org/article/0d6245895b2e42a080e1391355fcd9ae
Autor:
Nikki Clauss, Anthony Owens, Melissa Vitela, Melodi Bowman, Geogianna Gould, Wouter Koek, Lynette Daws
Publikováno v:
The FASEB Journal. 35
Autor:
Hsiao Huei Wu, Lynette C. Daws, Harald H. Sitte, Wouter Koek, Isabella Salzer, W. Anthony Owens, Stefan Boehm, Oliver Kudlacek, Piper H. Williams, Mia Apuschkin, Georgianna G. Gould, Peter Chiba, Ulrik Gether, Diethart Schmid, Felix P. Mayer
Publikováno v:
Mayer, F P, Schmid, D, Owens, W A, Gould, G G, Apuschkin, M, Kudlacek, O, Salzer, I, Boehm, S, Chiba, P, Williams, P H, Wu, H-H, Gether, U, Koek, W, Daws, L C & Sitte, H H 2018, ' An unsuspected role for organic cation transporter 3 in the actions of amphetamine ', Neuropsychopharmacology, vol. 43, pp. 2408-2417 . https://doi.org/10.1038/s41386-018-0053-5
Neuropsychopharmacology
Neuropsychopharmacology
Amphetamine abuse is a major public health concern for which there is currently no effective treatment. To develop effective treatments, the mechanisms by which amphetamine produces its abuse-related effects need to be fully understood. It is well kn
Autor:
Nicole Speed, Christine Saunders, Adeola R Davis, W Anthony Owens, Heinrich J G Matthies, Sanaz Saadat, Jack P Kennedy, Roxanne A Vaughan, Rachael L Neve, Craig W Lindsley, Scott J Russo, Lynette C Daws, Kevin D Niswender, Aurelio Galli
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25169 (2011)
BackgroundThe prevalence of obesity has increased dramatically worldwide. The obesity epidemic begs for novel concepts and therapeutic targets that cohesively address "food-abuse" disorders. We demonstrate a molecular link between impairment of a cen
Externí odkaz:
https://doaj.org/article/05ed995f3cb24c789dbad3cf779f0c17
Autor:
Jason M Williams, W Anthony Owens, Gregory H Turner, Christine Saunders, Concetta Dipace, Randy D Blakely, Charles P France, John C Gore, Lynette C Daws, Malcolm J Avison, Aurelio Galli
Publikováno v:
PLoS Biology, Vol 5, Iss 10, p e274 (2007)
The behavioral effects of psychomotor stimulants such as amphetamine (AMPH) arise from their ability to elicit increases in extracellular dopamine (DA). These AMPH-induced increases are achieved by DA transporter (DAT)-mediated transmitter efflux. Re
Externí odkaz:
https://doaj.org/article/e61452d86ad3472b8a241502322e631b
Publikováno v:
The FASEB Journal. 33
Publikováno v:
The FASEB Journal. 32
Autor:
Deana M. Apple, Wouter Koek, Sonia Cano, Nathan C. Mitchell, W. Anthony Owens, Melissa Vitela, Nicole L. Baganz, Lynette C. Daws, Georgianna G. Gould, Rebecca E. Horton
Publikováno v:
Journal of Neuroscience. 33:10534-10543
Mood disorders cause much suffering and lost productivity worldwide, compounded by the fact that many patients are not effectively treated by currently available medications. The most commonly prescribed antidepressant drugs are the selective seroton
Publikováno v:
Neuromethods ISBN: 9781493937639
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f527591c5f984a18dfbf416466e9ccfd
https://doi.org/10.1007/978-1-4939-3765-3_4
https://doi.org/10.1007/978-1-4939-3765-3_4
Autor:
Ana Carneiro, Elaine Sanders-Bush, Charisma R. Shah, W. Anthony Owens, Brent J. Thompson, Hideki Iwamoto, Ran Ye, Jennifer E. Sauer, Padmanabhan Mannangatti, Douglas G. McMahon, James S. Sutcliffe, Jordan Cohen, Lynette C. Daws, Randy D. Blakely, Jacqueline N. Crawley, Christopher L. Muller, Travis M. Kerr, Sammanda Ramamoorthy, Jeremy Veenstra-VanderWeele, Tammy Jessen
Publikováno v:
Proceedings of the National Academy of Sciences. 109:5469-5474
Fifty years ago, increased whole-blood serotonin levels, or hyperserotonemia, first linked disrupted 5-HT homeostasis to Autism Spectrum Disorders (ASDs). The 5-HT transporter (SERT) gene ( SLC6A4 ) has been associated with whole blood 5-HT levels an