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pro vyhledávání: '"Anthony Olarerin-George"'
Autor:
Robert J.J. Jansens, Anthony Olarerin-George, Ruth Verhamme, Aashiq Mirza, Samie Jaffrey, Herman W. Favoreel
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107310- (2023)
Summary: The mechanisms by which viruses regulate host mRNAs during infection are still poorly understood. Several host transcripts that encode proteins that contribute to the anti-viral response contain the N6-methyladenosine nucleotide (m6A). In th
Externí odkaz:
https://doaj.org/article/e57474c9300949e4b9427ebb94b1dd9e
Autor:
Lauren Anton, Ann DeVine, Erzsebet Polyak, Anthony Olarerin-George, Amy G. Brown, Marni J. Falk, Michal A. Elovitz
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Preeclampsia is associated with first trimester placental dysfunction. miR-210, a small non-coding RNA, is increased in the preeclamptic placenta. The effects of elevated miR-210 on placental function remain unclear. The objectives of this study were
Externí odkaz:
https://doaj.org/article/c806569c0f524865aa399ef75ec565a9
Autor:
Robert J.J. Jansens, Ruth Verhamme, Aashiq H. Mirza, Anthony Olarerin-George, Cliff Van Waesberghe, Samie R. Jaffrey, Herman W. Favoreel
Publikováno v:
CELL REPORTS
Chemical modifications of mRNA, the so-called epitranscriptome, represent an additional layer of post -tran-scriptional regulation of gene expression. The most common epitranscriptomic modification, N6-methylade-nosine (m6A), is generated by a multi-
Autor:
Ryan J, Ries, Sara, Zaccara, Pierre, Klein, Anthony, Olarerin-George, Sim, Namkoong, Brian F, Pickering, Deepak P, Patil, Hojoong, Kwak, Jun Hee, Lee, Samie R, Jaffrey
Publikováno v:
Nature
N6-methyladenosine (m6A) is the most prevalent modified nucleotide in mRNA1,2, with ~25% of mRNAs containing at least one m6A. Methylation of mRNA to form m6A is required for diverse cellular and physiological processes3. Although the presence of m6A