Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Anthony O. King"'
Autor:
Nobuyoshi Yasuda, Anthony O. King
Publikováno v:
Organometallics in Process Chemistry ISBN: 9783540016038
Organometallics in Process Chemistry
Organometallics in Process Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b624542463d8ab54e2f3ea72bc8e0d0
https://doi.org/10.1007/b94551
https://doi.org/10.1007/b94551
Autor:
Chie Kadowaki, Yoshinori Kohmura, Donald R. Gauthier, Kazunobu Igawa, David A. Conlon, Shinji Kato, Shigemitsu Okada, Anthony O. King, Yong-Li Zhong, Brenda Pipik, Akihiro Takezawa, Robert A. Reamer, Jaemoon Lee, Hua Zhou, David Askin
Publikováno v:
Organic Process Research & Development. 12:1245-1252
A practical and efficient synthesis of the potent HIV integrase inhibitor 1 is described. Starting from readily available 3,4-dihydro-2H-pyran, the six-step synthesis features a through process without purification of any of the intermediates until t
Autor:
Rob D. Larsen, Ralph P. Volante, Michel Journet, Ali Shafiee, Mirlinda Biba, Edward J. J. Grabowski, Anthony O. King, Jean-François Marcoux, Dalian Zhao, Veena Upadhyay, Kevin R. Campos, Edward G. Corley, Richard D. Tillyer
Publikováno v:
Tetrahedron: Asymmetry. 16:3094-3098
Three racemic esters including indole-ethyl ester 1 as well as its related derivatives 3 and 4 in Scheme 1, all synthetic intermediates for the preparation of chiral compound 5 , were used as substrates to evaluate the catalytic potentials of a panel
Autor:
David M. Tschaen, Fengrui Lang, Edward G. Corley, Kimberly A. Savary, Feng Xu, Jimmy O. DaSilva, Amude M. Kassim, Anthony O. King, Robert D. Larsen, Peter G. Dormer, Johnnie L. Leazer, Lisa DiMichele
Publikováno v:
Tetrahedron Letters. 45:5429-5432
A general method for the preparation of syn -2,3-disubstituted-2,3-dihydro-1,4-benzoxathiin rings from 2-mercaptoethanols and quinone ketals is presented. This ring system is produced by Michael addition of a 2-mercaptoethanol to a quinone ketal, fol
Autor:
Xin Wang, Weirong Chen, Lushi Tan, Paul J. Reider, Lisa F. Frey, Philippe Dagneau, Anthony O. King, Cheng-yi Chen, Richard D. Tillyer, Feng Xu, Edward J. J. Grabowski, Paul D. O’Shea, Dalian Zhao
Publikováno v:
Tetrahedron. 58:7403-7410
Two synthetic strategies to the COX-2 specific inhibitor 1 have been described that allowed its preparation in large quantities in 79% overall yield from (S)-2-hydroxy-2-methylbutyric acid. These studies have led to the identification of an efficient
Autor:
Sarah Stahl, Xin Wang, Richard D. Tillyer, Philippe Dagneau, Paul D. O’Shea, Anthony O. King, Michel Chartrain, Randolph Greasham
Publikováno v:
Biocatalysis and Biotransformation. 18:471-477
The screening of 144 microbial strains yielded several suitable biocatalysts for the asymmetric bioreduction of an allylic ketosulfone to its corresponding (R)-alcohol. The production of the desired enantiomer with elevated optical purity (ee > 90%)
Asymmetric direduction of 1,2-indanedione to cis (1S,2R) indanediol by Trichosporon cutaneum MY 1506
Publikováno v:
Journal of Bioscience and Bioengineering. 88:495-499
Cis (1 S ,2 R ) indanediol is a potential precursor to (−)- cis (1 S ,2 R )-1-aminoindan-2-ol, a key chiral synthon for a leading HIV protease inhibitor, Crixivan® (Indinavir). A potential route to the biosynthesis of this important precursor, the
Autor:
Margaret M. Faul, Xianghong Wang, Emilio E. Bunel, Laurie B. Schenkel, Johann Chan, Robert D. Larsen, Anthony O. King, Paul J. Reider, Michael J. Martinelli, John G. Allen, Anil S. Guram
Publikováno v:
Organic Letters. 8:1787-1789
[reaction: see text] New air-stable PdCl(2){P(t)Bu(2)(p-R-Ph)}(2) (R = H, NMe(2), CF(3),) complexes represent simple, general, and efficient catalysts for the Suzuki-Miyaura cross-coupling reactions of aryl halides including five-membered heteroaryl
Publikováno v:
Tetrahedron Letters. 38:2641-2644
A convenient and economical in situ preparation of DIP-Chloride tm from NaBH4, BCl3 and α-pinene is described. Its application in the asymmetric reduction of representative aralkyl ketones is presented.