Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Anthony Novell"'
Autor:
Allegra Conti, Francoise Geffroy, Hermes A. S. Kamimura, Anthony Novell, Nicolas Tournier, Sébastien Mériaux, Benoit Larrat
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15488 (2022)
The blood-brain barrier (BBB) controls brain homeostasis; it is formed by vascular endothelial cells that are physically connected by tight junctions (TJs). The BBB expresses efflux transporters such as P-glycoprotein (P-gp) and breast cancer resista
Externí odkaz:
https://doaj.org/article/c52c5a2f9260499d9151b659b5641bc2
Autor:
Chiara Bastiancich, Samantha Fernandez, Florian Correard, Anthony Novell, Benoit Larrat, Benjamin Guillet, Marie-Anne Estève
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2227 (2022)
Glioblastoma (GBM) is an aggressive and malignant primary brain tumor. The blood-brain barrier (BBB) limits the therapeutic options available to tackle this incurable tumor. Transient disruption of the BBB by focused ultrasound (FUS) is a promising a
Externí odkaz:
https://doaj.org/article/9586a11a8181499d9d361d611d5bdd62
Publikováno v:
Frontiers in Physics, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/b06dde9ab278421da96a0a381e20e6f2
Autor:
Charlotte Bérard, Stéphane Desgranges, Noé Dumas, Anthony Novell, Benoit Larrat, Mourad Hamimed, Nicolas Taulier, Marie-Anne Estève, Florian Correard, Christiane Contino-Pépin
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1498 (2022)
The management of brain diseases remains a challenge, particularly because of the difficulty for drugs to cross the blood–brain barrier. Among strategies developed to improve drug delivery, nano-sized emulsions (i.e., nanoemulsions), employed as na
Externí odkaz:
https://doaj.org/article/47fe15a5d2e34e3db4a06336a18d74b6
Publikováno v:
Frontiers in Physics, Vol 8 (2020)
Since its discovery in 2001, the interest in the low-intensity focused ultrasound (FUS)-mediated blood-brain barrier (BBB) disruption to deliver genes and drugs to brain tissue has increased steadily. Increasingly sophisticated sonication protocols a
Externí odkaz:
https://doaj.org/article/2ea4ca25656747d78408bdc50f1ba922
Autor:
Gaëlle Hugon, Sébastien Goutal, Ambre Dauba, Louise Breuil, Benoit Larrat, Alexandra Winkeler, Anthony Novell, Nicolas Tournier
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1752 (2021)
Focused ultrasound in combination with microbubbles (FUS) provides an effective means to locally enhance the delivery of therapeutics to the brain. Translational and quantitative imaging techniques are needed to noninvasively monitor and optimize the
Externí odkaz:
https://doaj.org/article/8725d3f997024c7cada22894fcce8252
Autor:
Marie-Solenne Felix, Emilie Borloz, Khaled Metwally, Ambre Dauba, Benoit Larrat, Valerie Matagne, Yann Ehinger, Laurent Villard, Anthony Novell, Serge Mensah, Jean-Christophe Roux
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1245 (2021)
Gene therapy represents a powerful therapeutic tool to treat diseased tissues and provide a durable and effective correction. The central nervous system (CNS) is the target of many gene therapy protocols, but its high complexity makes it one of the m
Externí odkaz:
https://doaj.org/article/9ae232de04cf41178cf94772dee6a02c
Autor:
Ambre Dauba, Anthony Delalande, Hermes A. S. Kamimura, Allegra Conti, Benoit Larrat, Nicolas Tsapis, Anthony Novell
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1125 (2020)
The blood-brain barrier is the primary obstacle to efficient intracerebral drug delivery. Focused ultrasound, in conjunction with microbubbles, is a targeted and non-invasive way to disrupt the blood-brain barrier. Many commercially available ultraso
Externí odkaz:
https://doaj.org/article/e4126ff1b52c4c018066200613739225
Autor:
Solène Marie, Irene Hernández-Lozano, Louise Breuil, Wadad Saba, Anthony Novell, Jean-Luc Gennisson, Oliver Langer, Charles Truillet, Nicolas Tournier
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 486 (2020)
The multidrug resistance-associated protein 2 (MRP2) mediates the biliary excretion of drugs and metabolites. [99mTc]mebrofenin may be employed as a probe for hepatic MRP2 activity because its biliary excretion is predominantly mediated by this trans
Externí odkaz:
https://doaj.org/article/a71a0ed0ba2f4ff096e080b6732a0ca2
Autor:
Chloé J Arthuis, Anthony Novell, Florian Raes, Jean-Michel Escoffre, Stéphanie Lerondel, Alain Le Pape, Ayache Bouakaz, Franck Perrotin
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169850 (2017)
PURPOSE:This preclinical study aimed to evaluate placental oxygenation in pregnant rats by real-time photoacoustic (PA) imaging on different days of gestation and to specify variations in placental oxygen saturation under conditions of maternal hypox
Externí odkaz:
https://doaj.org/article/cf010694b805466a83a17c4fdab76f1e