Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anthony Ndifor"'
Autor:
Jonathan D. Oliner, Robert Radinsky, Richard Kendall, Tom Boone, Luke Li, Donald M. McDonald, Beverly L. Falcón, Isaac J. Hayward, Anthony Ndifor, Shao Xiong Wang, Linh Nguyen, Eunju Hurh, Russell Cattley, Grant Shimamoto, Eric Hsu, Mark L. Michaels, Seog Joon Han, Haejin Kim, David Cordover, Paul Hughes, Sean Caenepeel, Karen Rex, Ling Wang, James McCabe, Brad Bolon, Juan Estrada, Ji-Rong Sun, Tani Ann Lee, Dongyin Yu, Juan Leal, Stephen Kaufman, Hosung Min, James Bready, Angela Coxon
Supplementary Figure 3 from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing Peptibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2934ed8c6f207f77eea17ceb99211e41
https://doi.org/10.1158/1535-7163.22486041.v1
https://doi.org/10.1158/1535-7163.22486041.v1
Autor:
Jonathan D. Oliner, Robert Radinsky, Richard Kendall, Tom Boone, Luke Li, Donald M. McDonald, Beverly L. Falcón, Isaac J. Hayward, Anthony Ndifor, Shao Xiong Wang, Linh Nguyen, Eunju Hurh, Russell Cattley, Grant Shimamoto, Eric Hsu, Mark L. Michaels, Seog Joon Han, Haejin Kim, David Cordover, Paul Hughes, Sean Caenepeel, Karen Rex, Ling Wang, James McCabe, Brad Bolon, Juan Estrada, Ji-Rong Sun, Tani Ann Lee, Dongyin Yu, Juan Leal, Stephen Kaufman, Hosung Min, James Bready, Angela Coxon
AMG 386 is an investigational first-in-class peptide-Fc fusion protein (peptibody) that inhibits angiogenesis by preventing the interaction of angiopoietin-1 (Ang1) and Ang2 with their receptor, Tie2. Although the therapeutic value of blocking Ang2 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28fc85f3746b4b3881e43684fd11d58a
https://doi.org/10.1158/1535-7163.c.6532206.v1
https://doi.org/10.1158/1535-7163.c.6532206.v1
Autor:
Jonathan D. Oliner, Robert Radinsky, Richard Kendall, Tom Boone, Luke Li, Donald M. McDonald, Beverly L. Falcón, Isaac J. Hayward, Anthony Ndifor, Shao Xiong Wang, Linh Nguyen, Eunju Hurh, Russell Cattley, Grant Shimamoto, Eric Hsu, Mark L. Michaels, Seog Joon Han, Haejin Kim, David Cordover, Paul Hughes, Sean Caenepeel, Karen Rex, Ling Wang, James McCabe, Brad Bolon, Juan Estrada, Ji-Rong Sun, Tani Ann Lee, Dongyin Yu, Juan Leal, Stephen Kaufman, Hosung Min, James Bready, Angela Coxon
Supplementary Methods, Figure Legends, and References from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing Peptibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f1f07abbb748f03b8d216b421c4503
https://doi.org/10.1158/1535-7163.22486035
https://doi.org/10.1158/1535-7163.22486035
Autor:
Jonathan D. Oliner, Robert Radinsky, Richard Kendall, Tom Boone, Luke Li, Donald M. McDonald, Beverly L. Falcón, Isaac J. Hayward, Anthony Ndifor, Shao Xiong Wang, Linh Nguyen, Eunju Hurh, Russell Cattley, Grant Shimamoto, Eric Hsu, Mark L. Michaels, Seog Joon Han, Haejin Kim, David Cordover, Paul Hughes, Sean Caenepeel, Karen Rex, Ling Wang, James McCabe, Brad Bolon, Juan Estrada, Ji-Rong Sun, Tani Ann Lee, Dongyin Yu, Juan Leal, Stephen Kaufman, Hosung Min, James Bready, Angela Coxon
Supplementary Figure 1 from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing Peptibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423e5ef205e090bf0f7e3fd936b186f7
https://doi.org/10.1158/1535-7163.22486047
https://doi.org/10.1158/1535-7163.22486047
Autor:
Jonathan D. Oliner, Robert Radinsky, Richard Kendall, Tom Boone, Luke Li, Donald M. McDonald, Beverly L. Falcón, Isaac J. Hayward, Anthony Ndifor, Shao Xiong Wang, Linh Nguyen, Eunju Hurh, Russell Cattley, Grant Shimamoto, Eric Hsu, Mark L. Michaels, Seog Joon Han, Haejin Kim, David Cordover, Paul Hughes, Sean Caenepeel, Karen Rex, Ling Wang, James McCabe, Brad Bolon, Juan Estrada, Ji-Rong Sun, Tani Ann Lee, Dongyin Yu, Juan Leal, Stephen Kaufman, Hosung Min, James Bready, Angela Coxon
Supplementary Figure 2 from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing Peptibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101a3ffc436ea2111d452cdf846600a7
https://doi.org/10.1158/1535-7163.22486044.v1
https://doi.org/10.1158/1535-7163.22486044.v1
Autor:
Jonathan D. Oliner, Robert Radinsky, Richard Kendall, Tom Boone, Luke Li, Donald M. McDonald, Beverly L. Falcón, Isaac J. Hayward, Anthony Ndifor, Shao Xiong Wang, Linh Nguyen, Eunju Hurh, Russell Cattley, Grant Shimamoto, Eric Hsu, Mark L. Michaels, Seog Joon Han, Haejin Kim, David Cordover, Paul Hughes, Sean Caenepeel, Karen Rex, Ling Wang, James McCabe, Brad Bolon, Juan Estrada, Ji-Rong Sun, Tani Ann Lee, Dongyin Yu, Juan Leal, Stephen Kaufman, Hosung Min, James Bready, Angela Coxon
Supplementary Figure 4 from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing Peptibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f0a5f009cdf18244a8365e54904ef38
https://doi.org/10.1158/1535-7163.22486038
https://doi.org/10.1158/1535-7163.22486038
Autor:
Anne E. Fitzgerald, Tatiana Koudriakova, Kevin J. Coe, Anthony Ndifor, Cathy Preville, Christine Dugovic, Neelakandha S. Mani, Nicholas I. Carruthers, Michele C. Rizzolio, Timothy W. Lovenberg, Brock T. Shireman, Diane Nepomuceno, Coate Heather R, Daniel J. Pippel, Brian Lord, Allison Brett Douglas, Curt A. Dvorak, Pascal Bonaventure
Publikováno v:
ACS Med Chem Lett
[Image: see text] The orexin system consists of two neuropeptides (orexin-A and orexin-B) that exert their mode of action on two receptors (orexin-1 and orexin-2). While the role of the orexin-2 receptor is established as an important modulator of sl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b157e2b40c4b8187c17e0918f6f2afc
https://doi.org/10.1021/acsmedchemlett.0c00085
https://doi.org/10.1021/acsmedchemlett.0c00085
Publikováno v:
Toxicologic pathology. 49(6)
Fetal examinations in embryo-fetal developmental (EFD) studies are based on macroscopic and dissecting microscopic evaluations, and histopathology is rarely performed other than to confirm macroscopic findings. Fetal lens examination is therefore gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4c0e8a4f5da422a1082be0091ebdd7
https://pubmed.ncbi.nlm.nih.gov/34128434
https://pubmed.ncbi.nlm.nih.gov/34128434
Autor:
James R Shoblock, Sandra R. Chaplan, Anthony Ndifor, Steven W. Sutton, Nicholas I. Carruthers, Robin Halter, Michele C. Rizzolio, Ian Fraser, Tatiana Koudriakova, Pascal Bonaventure, Sujin Yun, Leah Aluisio, Christine Dugovic, Zuleima Aguilar, Jonathan Shelton, Brian Lord, Natalie Welty, Timothy W. Lovenberg, Michael A. Letavic, Diane Nepomuceno
Publikováno v:
ResearcherID
Dual orexin receptor antagonists have been shown to promote sleep in various species, including humans. Emerging research indicates that selective orexin-2 receptor (OX2R) antagonists may offer specificity and a more adequate sleep profile by preserv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a22e350290152292370d7db2d63f57
https://doi.org/10.1124/jpet.115.225466
https://doi.org/10.1124/jpet.115.225466
Autor:
Ann J. Barbier, Steven B Sands, Lilian Y Li, Anthony Ndifor, Chandra R. Shah, Kirsten L. Morton, Michael A. Letavic, Timothy W. Lovenberg, Anne Bonneville, Heather McAllister, Neelakandha S. Mani, Ian Fraser, Kiev S. Ly, Richard Apodaca, Nicholas I. Carruthers, Manoj Bajpai, Swanson Devin M, Michelle Kramer, Christine Dugovic, Sandra S Snook, Chennagiri R. Pandit, Jonathan Shelton, Wei Xiao, Leah Aluisio, Pascal Bonaventure, Brian Lord, S Diane Nepomuceno
Publikováno v:
ACS Medicinal Chemistry Letters. 6:450-454
The preclinical characterization of novel phenyl(piperazin-1-yl)methanones that are histamine H3 receptor antagonists is described. The compounds described are high affinity histamine H3 antagonists. Optimization of the physical properties of these h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb111c3b07b944a678c3abee290cc57f
https://doi.org/10.1021/ml5005156
https://doi.org/10.1021/ml5005156