Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Anthony M. Edwards"'
Autor:
M. N. Berry, Anthony M. Edwards
It is thirty years since the technique of high-yield preparation of isolated hepatocytes, by collagenase perfusion of the liver, was published. The original method described by Berry and Friend has undergone many minor modifications by other workers,
Autor:
Anthony M. Edwards, Chow H. Lee
Publikováno v:
Journal of Cellular Physiology. 187:336-344
Studies in vivo using inhibitors of eicosanoid synthesis suggested that prostaglandins may play a role in mediating tumor promotion in liver by agents such as phenobarbital (PB). However, it is not clear whether any stimulation of arachidonic acid me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6203ed01da11539a7e2efcfad7c3c66
https://doi.org/10.1002/jcp.1083
https://doi.org/10.1002/jcp.1083
Publikováno v:
Journal of cellular physiology. 195(1)
The mechanisms of tumor promotion in liver by various xenobiotics of diverse structure are not well understood. However, these tumor promoters share the ability to exert growth-stimulatory effects on hepatocytes. Our laboratory has been utilizing nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630616f9554d1cf865dc51dab9838a0e
https://pubmed.ncbi.nlm.nih.gov/12599209
https://pubmed.ncbi.nlm.nih.gov/12599209
Autor:
Anthony M. Edwards, Chow H. Lee
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 81(1)
Among the chemical compounds of varied structure which possess liver tumour-promoting are steroids, such as estrogens, pregnenolone derivatives and anabolic steroids. Although the mechanism(s) of tumour promotion in liver by these xenobiotics is not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34db8dc64a5053d360544d27ce49c6b3
https://pubmed.ncbi.nlm.nih.gov/12127039
https://pubmed.ncbi.nlm.nih.gov/12127039
Autor:
Chow H. Lee, Anthony M. Edwards
Publikováno v:
Archives of toxicology. 77(3)
Mechanism(s) of tumour promotion in liver by estrogens and other xenobiotics such as alpha-hexachlorocyclohexane (HCH), 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) and phenobarbital (PB), are not well understood although it is clear that grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f37f82fe922702aa29ecb914a6331f6
https://pubmed.ncbi.nlm.nih.gov/12632255
https://pubmed.ncbi.nlm.nih.gov/12632255
Autor:
Anthony M. Edwards, Chow H. Lee
Publikováno v:
Carcinogenesis. 22(9)
The mechanism(s) of tumour promotion in liver by estrogens is not well understood although growth stimulation is known to be one important element of their action. As a basis for studying mechanisms of growth control by estrogens, effects of both nat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::532684d68961df1036ba196e0c6f7c71
https://pubmed.ncbi.nlm.nih.gov/11532870
https://pubmed.ncbi.nlm.nih.gov/11532870
Publikováno v:
The Hepatocyte Review ISBN: 9789048154029
Investigators have a variety of reasons for studying the factors that determine the ability of hepatocytes to grow, and for pursuing some of these studies utilising the relatively defined and easily-manipulated conditions of cell culture. There are i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1419065cff4e04ec327314b5524e0a58
https://doi.org/10.1007/978-94-017-3345-8_7
https://doi.org/10.1007/978-94-017-3345-8_7
Autor:
Anthony M. Edwards, Michael N. Berry
Publikováno v:
The Hepatocyte Review
Acknowledgements. Preface. Isolated hepatocytes: forty years on M.N. Berry. Isolation and culture of human hepatocytes M.J. Gomez-Lechon, J.V. Castell. Isolation and culture of porcine hepatocytes H.G. Koebe, et al. Preparation and properties of isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1969ae34bf32ca7ea94e97173bbc935f
https://doi.org/10.1007/978-94-017-3345-8
https://doi.org/10.1007/978-94-017-3345-8
Publikováno v:
Journal of cellular physiology. 155(1)
This study examines the effects of extracellular Ca2+ concentrations, [Ca2+]o, and of treatments known to modulate intracellular Ca2+ levels on the extent and timing of DNA synthesis in primary cultures of adult rat hepatocytes. In cultures exposed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a92f7829973aa6346b3dff5142d09bdf
https://pubmed.ncbi.nlm.nih.gov/8468368
https://pubmed.ncbi.nlm.nih.gov/8468368
Publikováno v:
Carcinogenesis. 11(5)
Mechanism(s) of tumor promotion in liver by xenobiotics such as hexachlorocyclohexane (HCH), 1,1,1-trichloro-2,2-bis (4-chlorophenyl)ethane (DDT) and phenobarbital (PB) are not understood in detail although growth-stimulatory effects may be significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c31511e382f7bd384767848075a9bb
https://pubmed.ncbi.nlm.nih.gov/1692266
https://pubmed.ncbi.nlm.nih.gov/1692266