Výsledky vyhledávání - "Anthony M. Cumming"

Contact Activation Inhibition and Platelet Rich Plasma Are Required in Order to Differentiate Bleeders from Non-Bleeders in FXI Deficiency Using the Thrombin Generation Assay

Autor: Charles R. M. Hay, Paula H B Bolton-Maggs, Gillian N Pike, Jecko Thachil, John Burthem, Anthony M Cumming

Publikováno v: Blood. 124:696-696

Introduction: FXI deficiency is characterised by a variable bleeding tendency. No clear correlation exists between bleeding and either FXI:C level or genotype. Some patients with major FXI deficiency (FXI:C Aims: To identify the optimal TG assay cond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4489a7d0be7faa1f1e794b489e7f741f
https://doi.org/10.1182/blood.v124.21.696.696

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Two Factor XI Concentrates Correct Impaired Thrombin Generation in Major FXI Deficiency but Are Not Equivalent in Their Effect

Autor: Megan Sutherland, Jecko Thachil, John Burthem, Brenda Sempasa, Paula H B Bolton-Maggs, Gillian N Pike, Anthony M Cumming, Charles R. M. Hay

Publikováno v: Blood. 124:1519-1519

Introduction: Factor XI (FXI) deficiency is an autosomally inherited bleeding disorder characterised by an increased risk of excessive bleeding following trauma or surgery. However, considerable phenotypic heterogeneity of the bleeding tendency is ob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c7f4397bd6b93190980ccff13afce5d
https://doi.org/10.1182/blood.v124.21.1519.1519

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Polymerase chain reaction amplification of two polymorphic simple repeat sequences within the von Willebrand factor gene: application to family studies in von Willebrand disease

Autor: Richard T. Wensley, Anthony M. Cumming, Aileen M Burn, Kate Pendry, John G. Armstrong

Publikováno v: Human genetics. 89(2)

We have used the polymerase chain reaction to amplify two variable number of tandem repeats (VNTRs) within a region of repetitive DNA located in intron 40 of the von Willebrand factor (vWf) gene. Heterozygosity for VNTR I was observed in 30 out of 39

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebd3955376f378ae51c4bc15576f659
https://pubmed.ncbi.nlm.nih.gov/1587530

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