Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Anthony M. Carr"'
Autor:
Sarah K. Wooller, Samantha Dias, Lisa Woodbine, Frances M. G. Pearl, Graeme Benstead-Hume, Anthony M. Carr
In this paper we explore computational approaches that enable us to identify genes that have become essential in individual cancer cell lines. Using recently published experimental cancer cell line gene essentiality data, human protein-protein intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8fae2c7e09b1da2b84c1b73b75929d
Autor:
Sarah Lambert, Jackie A. Pearce, Peter J. McHugh, Sarah J. Mason, Louise J. Barber, Anthony M. Carr, John A. Hartley
Drugs that produce covalent interstrand cross-links (ICLs) in DNA remain central to the treatment of cancer, but the cell cycle checkpoints activated by ICLs have received little attention. We have used the fission yeast, Schizosaccharomyces pombe, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1278b4f5e37adb440084da9c034dbc7e
https://ora.ox.ac.uk/objects/uuid:dd7ff598-3167-420a-9791-25fd9549d42d
https://ora.ox.ac.uk/objects/uuid:dd7ff598-3167-420a-9791-25fd9549d42d
Publikováno v:
Molecular Biology of the Cell. 15:851-860
A coordinated transcriptional response to DNA-damaging agents is required to maintain genome stability. We have examined the global gene expression responses of the fission yeast Schizosaccharomyces pombe to ionizing radiation (IR) by using DNA micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d0335b190a6252e2a616ef97a05066
https://doi.org/10.1091/mbc.e03-08-0569
https://doi.org/10.1091/mbc.e03-08-0569
Autor:
Anthony M. Carr, Aera Jo, Fenghua Yuan, Gwang Hyeon Gwon, Yanbin Zhang, Yunje Cho, Youngchang Kim, Adam T. Watson, Youngran Kim, Yaqi Liu, Thomas J. Etheridge
Fanconi anemia (FA) is an autosomal recessive genetic disorder caused by defects in any of 15 FA genes responsible for processing DNA interstrand cross-links (ICLs). The ultimate outcome of the FA pathway is resolution of cross-links, which requires
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ec3ff50f45b30961c207c8976dd514
http://sro.sussex.ac.uk/id/eprint/50604/4/Genes_Dev.-2014-Gwon-2276-90.pdf
http://sro.sussex.ac.uk/id/eprint/50604/4/Genes_Dev.-2014-Gwon-2276-90.pdf
Autor:
Elaine M. Taylor, Anthony M. Carr
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1378:55-58
This meeting served to juxtapose the fundamental studies on the distinct pathways which maintain genomic stability with work that addresses the phenotypic consequences of loss of genomic stability in humans. This created an exciting environment where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::150dc0e7891917d183c2676d88df1780
https://doi.org/10.1016/s0304-419x(98)00025-0
https://doi.org/10.1016/s0304-419x(98)00025-0
Autor:
Anthony M. Carr, G. Paul H. van Heusden, Peter A. T. Schrader, Dominic J. F. Griffiths, Jon C. Ford, H. Yde Steensma, Thomas F. C. Chin-A-Woeng
Publikováno v:
European Journal of Biochemistry. 229:45-53
The 14-3-3 proteins comprise a family of highly conserved acidic proteins. Several activities have been ascribed to these proteins, including activation of tyrosine and tryptophan hydroxylases in the presence of calcium/calmodulin-dependent protein k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94d88995de69d83a1e80bb653a678ef9
https://doi.org/10.1111/j.1432-1033.1995.0045l.x
https://doi.org/10.1111/j.1432-1033.1995.0045l.x
Autor:
Per U. Christensen, Viesturs Simanis, Johanne M. Murray, Joanne Porte, Kirsten E. Mundt, Kay Hofmann, Thomas Caspari, Anthony M. Carr, Iain M. Hagan, Jonathan B. A. Millar, Constantinos Brikos
Publikováno v:
Current biology : CB. 9(23)
The COP9/signalosome complex is conserved from plant to mammalian cells. In Arabidopsis, it regulates the nuclear abundance of COP1, a transcriptional repressor of photomorphogenic development [1,2]. All COP (constitutive photomorphogenesis) mutants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704d503884d90c7aa6b41c45d266ae7d
https://pubmed.ncbi.nlm.nih.gov/10607571
https://pubmed.ncbi.nlm.nih.gov/10607571
Publikováno v:
Molecular biology of the cell. 10(9)
To survive damage to the genome, cells must respond by activating both DNA repair and checkpoint responses. Using genetic screens in the fission yeast Schizosaccharomyces pombe, we recently isolated new genes required for DNA damage checkpoint contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1962cd385ef2554560b75486b1ef387
https://pubmed.ncbi.nlm.nih.gov/10473635
https://pubmed.ncbi.nlm.nih.gov/10473635
Publikováno v:
Biochemical Society Transactions. 23:331S-331S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4de58078737e9c6f230d9a4d8cc729c
https://doi.org/10.1042/bst023331s
https://doi.org/10.1042/bst023331s
Autor:
Steven F. Lee, Helen Armes, Thomas J. Etheridge, Anthony M. Carr, Alex Herbert, David Klenerman, David Lando
Publikováno v:
Biophysical Journal. (2):199a
Super-resolution techniques such as PALM and STORM are an exciting development allowing researchers to break the diffraction limit imposed by the diffraction of light. Our group works on understanding the systems of DNA repair and replication restart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd7aa76d8ab0bafa2c34618166378a1