Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Anthony M. C. Brown"'
Autor:
Randall A Dass, Aishe A Sarshad, Brittany B Carson, Jennifer M Feenstra, Amanpreet Kaur, Ales Obrdlik, Matthew M Parks, Varsha Prakash, Damon K Love, Kristian Pietras, Rosa Serra, Scott C Blanchard, Piergiorgio Percipalle, Anthony M C Brown, C Theresa Vincent
Publikováno v:
PLoS Genetics, Vol 12, Iss 8, p e1006217 (2016)
Ribosome biogenesis is essential for cell growth and proliferation and is commonly elevated in cancer. Accordingly, numerous oncogene and tumor suppressor signaling pathways target rRNA synthesis. In breast cancer, non-canonical Wnt signaling by Wnt5
Externí odkaz:
https://doaj.org/article/5285d630defb47bba294796a1bfeabe4
Autor:
Natalia L. Klyachko, Anthony M. C. Brown, Valentina A. Shchedrina, A A Zakhariants, Irina G. Gazaryan, S V Kazakov
Publikováno v:
Biochemistry (Moscow). 85:908-919
Elevation of intracellular Zn2+ following ischemia contributes to cell death by affecting mitochondrial function. Zn2+ is a differential regulator of the mitochondrial enzyme lipoamide dehydrogenase (LADH) at physiological concentrations (Ka = 0.1 µ
Autor:
Kun-Liang Guan, Zongbing You, Shaoqiong Chen, Denis C. Guttridge, Cun-Yu Wang, Anthony M. C. Brown, Ormond A. MacDougald, Zhaocheng Zhang, Gerard I. Evan, Daniel Saims, Jan Kitajewski
Publikováno v:
The Journal of Cell Biology
Aberrant activation of the Wnt/β-catenin signaling pathway is associated with numerous human cancers and often correlates with the overexpression or amplification of the c-myc oncogene. Paradoxical to the cellular transformation potential of c-Myc i
Autor:
Alexander M Many, Anthony M C Brown
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101800 (2014)
The characterization of mammary stem cells, and signals that regulate their behavior, is of central importance in understanding developmental changes in the mammary gland and possibly for targeting stem-like cells in breast cancer. The canonical Wnt/
Externí odkaz:
https://doaj.org/article/03298891e4834cdfa88ecc480256a908
Autor:
Mohammad Adileh, Anthony M. C. Brown, Louise R. Howe, Stefan Klingler, Lixing Zhang, Julie R. White, Maria Laura Martin, Richard Kolesnick, Xiaojing Ma
Publikováno v:
Cellular Signalling. 29:41-51
Recent evidence suggests that mammary cells expressing R-spondin receptor and Wnt pathway regulator Lgr5, regarded as a stem cell marker in multiple tissues, might represent mammary stem cells (MaSCs). Whether L gr5 marks a multipotent subpopulation
Autor:
Melissa McDowell, Gerlinde R. Van de Walle, Leen Bussche, Bethany A Syracuse, Gat Rauner, Richard A. Cerione, Marc A. Antonyak, Anthony M. C. Brown
Publikováno v:
Journal of Biological Chemistry. 291:24390-24405
Signaling mechanisms that regulate mammary stem/progenitor cell (MaSC) self-renewal are essential for developmental changes that occur in the mammary gland during pregnancy, lactation, and involution. We observed that equine MaSCs (eMaSCs) maintain t
Autor:
Francisca E. Cara, María Pinto Molina, Jenny C. Chang, Esperanza Muñoz-Muela, Carmen Hernández-Brenes, Gerardo García-Rivas, José A. Lorente, Sergio Granados-Principal, Anthony M. C. Brown, Adrián González-González, Marina Cruz-Lozano, Pedro Sánchez-Rovira, Juan A. Marchal
Publikováno v:
European journal of nutrition. 58(8)
This study was aimed to determine the impact of hydroxytyrosol (HT), a minor compound found in olive oil, on breast cancer stem cells (BCSCs) and the migration capacity of triple-negative breast cancer (TNBC) cell lines through the alteration of epit
Autor:
Hui Yang, Irene F. Choi, Trevor Williams, Maurizio Risolino, Marta Losa, Anthony M. C. Brown, Sameer Khan, James C. A. Hart, C. Theresa Vincent, Licia Selleri, Bingsi Li, Laura Quintana, Elisabetta Ferretti, Jennifer M. Feenstra, Robert Aho, Irina Grishina, Patrick Lewicki
Publikováno v:
Development.
Human cleft lip with or without cleft palate (CL/P) is a common craniofacial abnormality caused by impaired fusion of the facial prominences. We have previously reported that in the mouse embryo epithelial apoptosis mediates fusion at the seam where
Autor:
Marta, Losa, Maurizio, Risolino, Bingsi, Li, James, Hart, Laura, Quintana, Irina, Grishina, Hui, Yang, Irene F, Choi, Patrick, Lewicki, Sameer, Khan, Robert, Aho, Jennifer, Feenstra, C Theresa, Vincent, Anthony M C, Brown, Elisabetta, Ferretti, Trevor, Williams, Licia, Selleri
Publikováno v:
Development (Cambridge, England). 145(5)
Human cleft lip with or without cleft palate (CL/P) is a common craniofacial abnormality caused by impaired fusion of the facial prominences. We have previously reported that, in the mouse embryo, epithelial apoptosis mediates fusion at the seam wher
Autor:
Laura M. Rowland, Peter T. Fox, Andrew Robinson, Anthony M. C. Brown, Elliot Hong, John T. Sladky, Elaine S. Kawano, Leonardo Profenna, Stephen A. McGuire, Paul M. Sherman, Patrick Grogan, David F. Tate, Beenish Patel, Peter Kochunov
Publikováno v:
ResearcherID
To demonstrate that U-2 pilot occupational exposure to hypobaria leads to increased incidence of white matter hyperintensities (WMH) with a more uniform distribution throughout the brain irrespective of clinical neurologic decompression sickness hist