Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Anthony M Ford"'
Publikováno v:
Leukemia. 37:47-52
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00157b2b346ebf3e05748cb473f82a0
https://doi.org/10.1038/s41375-022-01756-1
https://doi.org/10.1038/s41375-022-01756-1
Publikováno v:
Leukemia. 35:1258-1264
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5c45d2f03997b52c7c77489d97eb2c1
https://doi.org/10.1038/s41375-021-01211-7
https://doi.org/10.1038/s41375-021-01211-7
Autor:
Filipa Esteves, Joana M. Xavier, Anthony M. Ford, Cátia Rocha, Paul D.P. Pharoah, Carlos Caldas, Suet-Feung Chin, Ana-Teresa Maia
Introduction: Translation of genome-wide association study (GWAS) findings into preventive approaches is challenged by the identification of the causal risk variants and the understanding of the biological mechanisms by which they act. We present usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652175f5b0611071282c18e89f3ed6b5
https://hdl.handle.net/10400.1/18654
https://hdl.handle.net/10400.1/18654
Autor:
Sampada Bhagwat, Eva Duthil, Heidi Kiil Blomhoff, Marta Maria Burman, Seham Skah, Ellen Ruud, Elin Hallan Naderi, Karin Margaretha Gilljam, Nina Richartz, Anthony M. Ford
Publikováno v:
Blood Advances. 3:3181-3190
Acute lymphoblastic leukemia (ALL) develops in the bone marrow in the vicinity of stromal cells known to promote tumor development and treatment resistance. We previously showed that the cyclooxygenase (COX) inhibitor indomethacin prevents the abilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a454b1c8dddda9ff6ecd76fa7809badb
https://doi.org/10.1182/bloodadvances.2019000473
https://doi.org/10.1182/bloodadvances.2019000473
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1868:521-526
Childhood acute lymphoblastic leukaemia (ALL) with MLL rearrangement (MLL-r) is an aggressive disease still associated with a high mortality rate. Recent investigations have identified co-operating mutations in the RAS pathway and although the functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afec516f3cae726134cddf970356935
https://doi.org/10.1016/j.bbcan.2017.10.005
https://doi.org/10.1016/j.bbcan.2017.10.005
Autor:
Carle Grobbelaar, Anthony M. Ford
Publikováno v:
Journal of Oncology
Journal of Oncology, Vol 2019 (2019)
Journal of Oncology, Vol 2019 (2019)
Acute lymphoblastic leukaemia (ALL) is the most common cancer of childhood. Although the overall survival of children with ALL is now more than 90%, leukaemia remains one of the leading causes of death from disease. In developed countries, the overal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb535e23c36def63c1e30dda1f4b241d
https://pubmed.ncbi.nlm.nih.gov/31737072
https://pubmed.ncbi.nlm.nih.gov/31737072
Autor:
Yan-jing Tang, T. H. Liu, X. L. Guo, L. H. Zhang, L. Chen, Ying Huang, L. G. Liu, Tariq Enver, Q. J. Ye, Feng Liu, Dengli Hong, Anthony M. Ford, Li Wang, X. Liu, Jingyan Tang, Guo-Qiang Chen, H. Zhu, J. Q. Mi, Benshang Li, Y. Zhang
Publikováno v:
Leukemia. 31:1079-1086
The origin of cancers is associated with etiology as well as therapeutics. Several studies reveal that malignancies in children can originate in utero. However, a diagnostic approach to distinguish between cancers initiated pre- or postnatally is abs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700fe46b7613a8678e7faae0c554428e
https://doi.org/10.1038/leu.2016.313
https://doi.org/10.1038/leu.2016.313
Autor:
Christopher M, Kirkham, James N F, Scott, Xiaoling, Wang, Alastair L, Smith, Adam P, Kupinski, Anthony M, Ford, David R, Westhead, Peter G, Stockley, Roman, Tuma, Joan, Boyes
Publikováno v:
Molecular cell. 74(3)
V(D)J recombination is essential to generate antigen receptor diversity but is also a potent cause of genome instability. Many chromosome alterations that result from aberrant V(D)J recombination involve breaks at single recombination signal sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db3e6c6de0286f92592cebef5d9282ca
https://pubmed.ncbi.nlm.nih.gov/30905508
https://pubmed.ncbi.nlm.nih.gov/30905508
Autor:
Anthony M. Ford, Britt Gustafsson, Gustaf Leijonhufvud, Kristin Mattsson, Gordana Bogdanovic, Kim Ramme, Emma Honkaniemi
Publikováno v:
Pediatric bloodcancer. 65(11)
SCL/TAL1 interrupting locus (STIL)-T-cell acute leukaemia (TAL1) fusion genes are present in approximately 11-27% of children with paediatric T-cell acute lymphoblastic leukaemia (T-ALL), but the developmental timing of the rearrangement is still unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aaf30e651438c535c7149ce93b1dba3
https://pubmed.ncbi.nlm.nih.gov/29968961
https://pubmed.ncbi.nlm.nih.gov/29968961
PAX5alterations in genetically unclassified childhood Precursor B-cell acute lymphoblastic leukaemia
Autor:
Anthony M. Ford, Philip Ancliff, Sarah Inglott, Carryl Dryden, Irina Stasevich, Nicola Austin, Helena Kempski, Dilys Addy, Steve Chatters, Owen Williams, Jane Chalker
Publikováno v:
British Journal of Haematology. 171:263-272
Here, we report a high incidence of PAX5 abnormalities observed in 32/68 (47%) of patients with genetically unclassified childhood precursor B-cell acute lymphoblastic leukaemia (pre-B ALL). Various deletions, gains, mutations and rearrangements of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4d6f6e7f70f795854bd6867cf1f484
https://doi.org/10.1111/bjh.13543
https://doi.org/10.1111/bjh.13543