Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Anthony M Couturier"'
Autor:
Marjorie Fournier, Amélie Rodrigue, Larissa Milano, Jean-Yves Bleuyard, Anthony M Couturier, Jacob Wall, Jessica Ellins, Svenja Hester, Stephen J Smerdon, László Tora, Jean-Yves Masson, Fumiko Esashi
Publikováno v:
eLife, Vol 11 (2022)
The tumour suppressor PALB2 stimulates RAD51-mediated homologous recombination (HR) repair of DNA damage, whilst its steady-state association with active genes protects these loci from replication stress. Here, we report that the lysine acetyltransfe
Externí odkaz:
https://doaj.org/article/5d62dc5a4b634c96b8938dd0c1b86dd9
Autor:
Martijn S Luijsterburg, Dimitris Typas, Marie-Christine Caron, Wouter W Wiegant, Diana van den Heuvel, Rick A Boonen, Anthony M Couturier, Leon H Mullenders, Jean-Yves Masson, Haico van Attikum
Publikováno v:
eLife, Vol 6 (2017)
DNA double-strand breaks (DSB) elicit a ubiquitylation cascade that controls DNA repair pathway choice. This cascade involves the ubiquitylation of histone H2A by the RNF168 ligase and the subsequent recruitment of RIF1, which suppresses homologous r
Externí odkaz:
https://doaj.org/article/8ceed8f982b241459d4fdb5dea866975
Autor:
Denis Velic, Anthony M. Couturier, Maria Tedim Ferreira, Amélie Rodrigue, Guy G. Poirier, Fabrice Fleury, Jean-Yves Masson
Publikováno v:
Biomolecules, Vol 5, Iss 4, Pp 3204-3259 (2015)
For decades, radiotherapy and chemotherapy were the two only approaches exploiting DNA repair processes to fight against cancer. Nowadays, cancer therapeutics can be a major challenge when it comes to seeking personalized targeted medicine that is bo
Externí odkaz:
https://doaj.org/article/4f2b0fefb4634be288e144c58e4225c7
Autor:
Marjorie Fournier, Amélie Rodrigue, Larissa Milano, Jean-Yves Bleuyard, Anthony M Couturier, Jacob Wall, Jessica Ellins, Svenja Hester, Stephen J Smerdon, László Tora, Jean-Yves Masson, Fumiko Esashi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6424866fa079b9cbdcfe348f823190f5
https://doi.org/10.7554/elife.57736.sa2
https://doi.org/10.7554/elife.57736.sa2
Autor:
Anthony M. Couturier, Fumiko Esashi, Jessica L Ellins, Marjorie Fournier, Laszlo Tora, Svenja Hester, Stephen J. Smerdon, Jean-Yves Bleuyard
The tumour suppressor PALB2 stimulates error-free repair of DNA breaks, whilst its steady-state chromatin association protects active genes from genotoxic stress. Here, we report that the lysine acetyltransferases 2A and 2B (KAT2A/B), commonly known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cfb98dc02c9a411d11e2febf4fa1354
https://hal.archives-ouvertes.fr/hal-02992877/document
https://hal.archives-ouvertes.fr/hal-02992877/document
Autor:
Brian Josephson, Sarah Faulkner, Fumiko Esashi, Tom Watts, Anthony M. Couturier, Benjamin G. Davis
A wealth ofin vivoevidence demonstrates the physiological importance of histone H3 trimethylation at lysine 36 (H3K36me3), to which chromodomain-containing proteins, such as MRG15, bind preferentially compared to their dimethyl (H3K36me2) counterpart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ee0e8dc6f6c72c7e599cd23337657c
https://doi.org/10.1101/2020.04.30.070136
https://doi.org/10.1101/2020.04.30.070136
Autor:
Marjorie Fournier, Jean-Yves Bleuyard, Anthony M. Couturier, Jessica Ellins, Svenja Hester, Stephen J. Smerdon, László Tora, Fumiko Esashi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3265b3a76daa7140f4f167cdedab7ca6
https://doi.org/10.15252/rc.2022136566
https://doi.org/10.15252/rc.2022136566
Autor:
Anthony M. Couturier, Jean-Yves Masson, Stéphanie Bérubé, Joshi Niraj, Laure Guitton-Sert, Karine Drapeau, Yan Coulombe, Marie-Christine Caron
Publikováno v:
Nucleic Acids Research
Fanconi anemia (FA) is a recessive genetic disorder characterized by congenital abnormalities, progressive bone-marrow failure, and cancer susceptibility. The FA pathway consists of at least 21 FANC genes (FANCA-FANCV), and the encoded protein produc
Autor:
Amélie Rodrigue, Anthony M. Couturier, Jean-Yves Masson, Joshi Niraj, Anne-Marie Mes-Masson, Yan Coulombe, Anne-Marie Patenaude, Jason N. Berman, Graham Dellaire, Javier M. Di Noia, Victoria L. Bentley, Hubert Fleury, Joris Pauty
Publikováno v:
Nucleic Acids Research
APRIN (PDS5 cohesin associated factor B) interacts with both the cohesin complex and the BRCA2 tumor suppressor. How APRIN influences cohesion and DNA repair processes is not well understood. Here, we show that APRIN is recruited to DNA damage sites.
Autor:
Yan Coulombe, Graham Dellaire, Anthony M. Couturier, Joris Pauty, Amélie Rodrigue, Jean-Yves Masson, Marie-Christine Caron
Publikováno v:
Nucleic Acids Research
Europe PubMed Central
Europe PubMed Central
One typical mechanism to promote genomic instability, a hallmark of cancer, is to inactivate tumor suppressors, such as PALB2. It has recently been reported that mutations in PALB2 increase the risk of breast cancer by 8–9-fold by age 40 and the li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94d0a27827034bbe0f713bcf724be06
https://ora.ox.ac.uk/objects/uuid:2587c05b-6d15-45df-a00d-9a2671922ee8
https://ora.ox.ac.uk/objects/uuid:2587c05b-6d15-45df-a00d-9a2671922ee8