Výsledky vyhledávání - "Anthony La Delfa"

Implementation and Evaluation of an IPAC SWAT Team Mobilized to Long-Term Care and Retirement Homes During the COVID-19 Pandemic: A Pragmatic Health System Innovation

Autor: Anthony La Delfa, Kevin Katz, Monakshi Sawhney, James Schembri, Diana Adams, Karoleen Abdel-Shahied, Michael J. Lamb, Tamara Belfer

Publikováno v: Journal of the American Medical Directors Association

Long-term care facilities (LTCFs), retirement homes (RHs), and other congregate care settings in Canada and worldwide have experienced significant COVID-19 outbreaks. As a health system response, our acute care hospital in Toronto, Ontario, Canada, d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a038a7cf3e2ecb173e7ff7b7993b83ac
http://europepmc.org/articles/PMC7833812

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Second-Hand Smoke As a Predictor of Smoking Cessation Among Lung Cancer Survivors

Autor: Frances A. Shepherd, Prakruthi R. Palepu, Luke Harland, Geoffrey Liu, Steven Habbous, Aidin Kashigar, Natasha B. Leighl, David P. Goldstein, Lawson Eng, Ehab Fadhel, Henrique Hon, Sinead Cuffe, Xin Qiu, Andrew Pierre, Jie Su, Anthony La Delfa, Wei Xu, Peter Selby

Publikováno v: Journal of Clinical Oncology. 32:564-570

Purpose Second-hand smoke (SHS; ie, exposure to smoking of friends and spouses in the household) reduces the likelihood of smoking cessation in noncancer populations. We assessed whether SHS is associated with cessation rates in lung cancer survivors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5064a0f1e73fe25b514815614fdab9
https://doi.org/10.1200/jco.2013.50.9695

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Comorbidity and prognosis in head and neck cancers: Differences by subsite, stage, and human papillomavirus status

Autor: Anthony La Delfa, Shao Hui Huang, John Waldron, Fei-Fei Liu, Ehab Fadhel, Luke Harland, Brian O'Sullivan, Steven Habbous, David P. Goldstein, Geoffrey Liu, Wei Xu

Publikováno v: Head & Neck. 36:802-810

Background The prognostic utility of comorbidity on head and neck cancer may differ by subsite, stage, and human papillomavirus (HPV) status. Methods We reviewed the medical records of 4953 patients with head and neck cancer for comorbidity (Charlson

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e0135b571348a72cd84dca3e4f92583
https://doi.org/10.1002/hed.23360

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Ubiquitin-specific Protease 7 Is a Regulator of Ubiquitin-conjugating Enzyme UbE2E1*

Autor: Majda Mohamed, Feroz Sarkari, Vivian Saridakis, Yi Sheng, Faryal Shaikh, Rahima Khatun, Keith Wheaton, Anthony La Delfa, Lori Frappier, Cheryl H. Arrowsmith

Ubiquitin-specific protease 7 (USP7) is a deubiquitinating enzyme found in all eukaryotes that catalyzes the removal of ubiquitin from specific target proteins. Here, we report that UbE2E1, an E2 ubiquitin conjugation enzyme with a unique N-terminal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a8035af8c58e82dabc558197973d68
https://europepmc.org/articles/PMC3675629/

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The changing incidence of human papillomavirus-associated oropharyngeal cancer using multiple imputation from 2000 to 2010 at a Comprehensive Cancer Centre

Autor: Ehab Fadhel, Bayardo Perez-Ordonez, John Waldron, Luke Harland, Wei Xu, Anthony La Delfa, Karen P. Chu, Brian O'Sullivan, Angela Hui, Ilan Weinreb, Steven Habbous, David Goldstein, Shao Hui Huang, Xin Qiu, Fei-Fei Liu, Geoffrey Liu

Publikováno v: Cancer epidemiology. 37(6)

Human papillomavirus (HPV) is a risk and prognostic factor for oropharyngeal cancer (OPC). Determining whether the incidence of HPV-associated OPC is rising informs health policy.HPV status was ascribed using p16 immunohistochemistry in 683/1474 OPC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5fbfab389df55959a748befb9f20905
https://pubmed.ncbi.nlm.nih.gov/24184275

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Validation of a one-page patient-reported Charlson comorbidity index questionnaire for upper aerodigestive tract cancer patients

Autor: Anthony La Delfa, John Waldron, Wei Xu, Shao Hui Huang, Luke Harland, Geoffrey Liu, Karen P. Chu, Ehab Fadhel, Brian O'Sullivan, Amy Wong, Doris Howell, Bin Sun, Jolie Ringash, Steven Habbous, David Goldstein

Publikováno v: Oral oncology. 49(5)

Cancer patients have a wide range of comorbidities that are important confounders for biomarker and clinical studies of prognosis and outcome. Comorbidities can be captured using the Charlson Comorbidity Index (CCI) through abstraction of medical rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4450bf4b8e4ab28cfb6b34910cf181b
https://pubmed.ncbi.nlm.nih.gov/23291295

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Further insight into substrate recognition by USP7: structural and biochemical analysis of the HdmX and Hdm2 interactions with USP7

Autor: Vivian Saridakis, Lori Frappier, Cheryl H. Arrowsmith, Anthony La Delfa, Feroz Sarkari, Yi Sheng

Publikováno v: Journal of molecular biology. 402(5)

Ubiquitin-specific protease 7 (USP7) catalyzes the deubiquitination of several substrate proteins including p53 and Hdm2. We have previously shown that USP7, and more specifically its amino-terminal domain (USP7-NTD), interacts with distinct regions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd428369d1866f2f1b30f7d7ff72043c
https://pubmed.ncbi.nlm.nih.gov/20713061

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Developing a comprehensive smoking cessation program in patients with lung cancer: The role of social smoking environments

Autor: Lawson Eng, Henrique Hon, Sinead Cuffe, Andrew Pierre, Aidin Kashigar, Anthony La Delfa, Steven Habbous, Natasha B. Leighl, Jie Su, Peter Selby, David P. Goldstein, Geoffrey Liu, Luke Harland, Ehab Fadhel, Wei Xu, Prakruthi R. Palepu, Xin Qiu

Publikováno v: Journal of Clinical Oncology. 30:75-75

75 Background: Smoking during cancer treatment negatively impacts outcome, survival, and quality of life. Social smoking environments (SSEs) (i.e., smoking in household, peers, and spouse) influence cessation rates in non-cancer patients, but are und

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b7919b07e96715b5ff01057a7d68a449
https://doi.org/10.1200/jco.2012.30.34_suppl.75

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Social environment as a predictor of smoking cessation and recidivism in lung cancer survivors

Autor: Anthony La Delfa, Luke Harland, Jie Su, Wei Xu, Natasha B. Leighl, Geoffrey Liu, Andrew Pierre, Prakruthi R. Palepu, David P. Goldstein, Aidin Kashigar, Lawson Eng, Henrique Hon, Sinead Cuffe, Steven Habbous, Ehab Fadhel

Publikováno v: Journal of Clinical Oncology. 30:9032-9032

9032 Background: Smoking during cancer treatment negatively impacts treatment, survival and quality of life. Lung cancer patients with a smoking history often continue to smoke; some ex-smokers re-start after diagnosis. Social environment impacts ces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7f4b16b0b593357ec63ba971b807d87d
https://doi.org/10.1200/jco.2012.30.15_suppl.9032

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Abstract 666: The effect of comorbidity, smoking and alcohol on survival of head and neck cancer anatomic subsites: A retrospective analysis of 4689 patients

Autor: Brian O'Sullivan, John W.F. Waldron, Angela Hui, Anthony La Delfa, Luke Harland, Geoffrey Liu, Karen P. Chu, Wei Xu, Shao Hui Huang, Steven Habbous, David Goldstein, Susie Su

Publikováno v: Cancer Research. 72:666-666

Background: Increased age and greater comorbidity are independent predictors of worse survival in nasopharyngeal and squamous cell cancers of the head and neck (HNC). The Charlson Comorbidity Index (CCI) provides a quantitative measure of comorbidity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc436274a9d1a8a32dd9a8e5aa681776
https://doi.org/10.1158/1538-7445.am2012-666

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