Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Anthony L DeVico"'
Autor:
Zahra Rikhtegaran Tehrani, Saman Saadat, Ebtehal Saleh, Xin Ouyang, Niel Constantine, Anthony L DeVico, Anthony D Harris, George K Lewis, Shyam Kottilil, Mohammad M Sajadi
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0237828 (2020)
There is an urgent need for an accurate antibody test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We have developed 3 ELISA methods, trimer spike IgA, trimer spike IgG, and nucleocapsid IgG, for detecting anti-SARS-CoV-2 antibod
Externí odkaz:
https://doaj.org/article/f5201487a4cd453aab1a89885fdc7429
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004772 (2015)
The HIV-1 envelope glycoprotein, gp120, undergoes multiple molecular interactions and structural rearrangements during the course of host cell attachment and viral entry, which are being increasingly defined at the atomic level using isolated protein
Externí odkaz:
https://doaj.org/article/1498c8861af24c17814d35e7d36923f7
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3481 (2008)
It is well established that paracrine secretion of anti-viral CCR5 ligands by CD8+ and CD4+ T cells can block the infection of activated CD4+ T cells by R5 and dual-tropic isolates of HIV-1. By contrast, because CD4+ T cells can be infected by HIV-1
Externí odkaz:
https://doaj.org/article/75e9c4b37a814b788ce5f8a598889d1c
Autor:
Andrew R. Crowley, Matthew R. Mehlenbacher, Mohammad M. Sajadi, Anthony L. DeVico, George K. Lewis, Margaret E. Ackerman
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTAntibody-mediated effector functions are widely considered to unfold according to an associative model of IgG-Fcγ receptor (FcγR) interactions. The associative model presupposes that Fc receptors cannot discriminate antigen-bound IgG from f
Externí odkaz:
https://doaj.org/article/5559437caf7c436bac7eade70d7f9afd
Autor:
Sameer Kumar, Souradip Dasgupta, Mohammad M. Sajadi, Greg A. Snyder, Anthony L. DeVico, Krishanu Ray
Publikováno v:
Viruses, Vol 16, Iss 3, p 407 (2024)
Efforts to develop vaccine and immunotherapeutic countermeasures against the COVID-19 pandemic focus on targeting the trimeric spike (S) proteins of SARS-CoV-2. Vaccines and therapeutic design strategies must impart the characteristics of virion S fr
Externí odkaz:
https://doaj.org/article/193ec3555637476e9a6bce05a277c5e1
Autor:
Ben Atkinson, Abdolrahim Abassi, Mohammad M. Sajadi, Zahra Rikhtegaran Tehrani, Nhut M. Le, Hegang H. Chen, Edward Sausville, Anthony L. DeVico, George K. Lewis, Xiaoxuan Fan, Alonso Heredia
Publikováno v:
AIDS Research and Human Retroviruses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d53235f185a05e18595475f4fb6fe96
https://doi.org/10.1089/aid.2022.0181
https://doi.org/10.1089/aid.2022.0181
Autor:
Lydiah Mutumbi, Guido Ferrari, Jennifer Schwartz, Charles E. L. B. Davis, Kelli Greene, Robin Flinko, Monica W. Gerber, Jennifer Husson, Raphael Gottardo, Amy Nelson, Joel V Chua, Celia Mahoney, Bruce L. Gilliam, Ka Wing J. Lam, George K. Lewis, Robert C. Gallo, Ilia Prado, Hongmei Gao, Georgia D. Tomaras, Dan Dong, William Fulp, Timothy R. Fouts, Nicole L. Yates, Mohammad M. Sajadi, Anthony L. DeVico, Bryan T. Mayer, David C. Montefiori
Publikováno v:
Vaccine
A major challenge for HIV vaccine development is to raise anti-envelope antibodies capable of recognizing and neutralizing diverse strains of HIV-1. Accordingly, a full length single chain (FLSC) of gp120-CD4 chimeric vaccine construct was designed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3541c6b8bcd449ca7fe0a723447b8758
https://doi.org/10.1016/j.vaccine.2021.05.090
https://doi.org/10.1016/j.vaccine.2021.05.090
Autor:
William D. Tolbert, Dung N. Nguyen, Marina Tuyishime, Andrew R. Crowley, Yaozong Chen, Shalini Jha, Derrick Goodman, Valerie Bekker, Sarah V. Mudrak, Anthony L. DeVico, George K. Lewis, James F. Theis, Abraham Pinter, M. Anthony Moody, David Easterhoff, Kevin Wiehe, Justin Pollara, Kevin O. Saunders, Georgia D. Tomaras, Margaret Ackerman, Guido Ferrari, Marzena Pazgier
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2022)
Frontiers in Immunology, Vol 12 (2022)
Passive transfer of monoclonal antibodies (mAbs) of human origin into Non-Human Primates (NHPs), especially those which function predominantly by a Fc-effector mechanism, requires an a priori preparation step, in which the human mAb is reengineered t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6569222b0302a8a78bb5336287122a7a
http://europepmc.org/articles/PMC8770954
http://europepmc.org/articles/PMC8770954
Publikováno v:
Trends in Molecular Medicine. 25:228-240
After years of continuous exposure to HIV envelope antigens, a minority of HIV-infected individuals develop a cognate polyclonal humoral response comprising very potent and extremely cross-reactive neutralizing antibodies [broadly neutralizing antibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbbaf9df4ca739cab60070b38b522414
https://doi.org/10.1016/j.molmed.2019.01.007
https://doi.org/10.1016/j.molmed.2019.01.007
Autor:
Young Do Kwon, Yin Lin, Paolo Lusso, Peng Zhang, Qingbo Liu, Anthony L. DeVico, Mohammad M. Sajadi, Michael S. Seaman, Zahra Rikhtegaran-Tehrani, Peter D. Kwong, Huiyi Miao
Publikováno v:
J Virol
Broadly neutralizing antibodies (bNAbs) are the focus of increasing interest for human immunodeficiency virus type-1 (HIV-1) prevention and treatment. Although several bNAbs are already under clinical evaluation, the development of antibodies with ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68439e54389c8b9d3014a01a4bd1d705
https://pubmed.ncbi.nlm.nih.gov/33827946
https://pubmed.ncbi.nlm.nih.gov/33827946