Zobrazeno 1 - 10
of 420
pro vyhledávání: '"Anthony L, Cunningham"'
Autor:
Lok Bahadur Shrestha, Katie Tungatt, Anupriya Aggarwal, Aija Stubis, Nicole L. Fewings, Christina Fichter, Anouschka Akerman, Chaturaka Rodrigo, Nicodemus Tedla, Sharon Lee, Andrew R. Lloyd, Fabienne Brilot, Warwick J. Britton, Anthony Kelleher, Ian D. Caterson, Mark W. Douglas, Rebecca Rockett, Stuart G. Tangye, James A. Triccas, Stuart G. Turville, Kerrie J. Sandgren, Rowena A. Bull, Anthony L. Cunningham, Tania Sorrell, Warwick Britton, Mark Maclean, Joanne Camilleri, Mark Douglas, Rowena Bull, Kerrie Sandgren, Yang Song, Lijun Mao, Amy Phu, Allison Sigmund, Sophie Beard, Ian Caterson, Stephanie Hunt, Anne Marie Vande More, Rama Kandasamy, Jen Kok, Jennifer Byrne, Andrew Lloyd, James Triccas, Stuart Tangye, Stuart Turville, Matthew O’Sullivan, Megan Steain, Sarah Baird, Chansavath Phetsouphanh, Yanran Zhao
Publikováno v:
EBioMedicine, Vol 110, Iss , Pp 105461- (2024)
Summary: Background: Current literature informs us that bivalent vaccines will generate a broader serum neutralizing antibody response to multiple SARS-CoV-2 variants, but studies on how this breadth relates to the memory B cell (MBC) and T cell resp
Externí odkaz:
https://doaj.org/article/dd032d7e0346406cbaf41c8673aab9d8
Publikováno v:
Infectious Diseases and Therapy, Vol 13, Iss 7, Pp 1439-1459 (2024)
Abstract Herpes zoster (HZ) is caused by reactivation of latent infection of varicella zoster virus (VZV) in sensory (cranial, dorsal root) ganglia. Major risk factors for HZ are increasing age and immunosuppression. HZ ophthalmicus (HZO) is a subset
Externí odkaz:
https://doaj.org/article/70065b6bbdcc4a0682d5d91d82263ffb
Publikováno v:
Viruses, Vol 16, Iss 11, p 1790 (2024)
Herpes simplex virus (HSV) is sexually transmitted via the anogenital mucosa where it initially infects epidermal keratinocytes and mononuclear phagocytes (MNPs). It then spreads to the dorsal root ganglion via sensory nerve endings, to remain latent
Externí odkaz:
https://doaj.org/article/85a962a98f954dafb7737d1b0559da3b
Autor:
Freja A Warner van Dijk, Orion Tong, Thomas R O'Neil, Kirstie M Bertram, Kevin Hu, Heeva Baharlou, Erica E Vine, Kate Jenns, Martijn P Gosselink, James W Toh, Tim Papadopoulos, Laith Barnouti, Gregory J Jenkins, Gavin Sandercoe, Muzlifah Haniffa, Kerrie J Sandgren, Andrew N Harman, Anthony L Cunningham, Najla Nasr
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1012351 (2024)
AXL+ Siglec-6+ dendritic cells (ASDC) are novel myeloid DCs which can be subdivided into CD11c+ and CD123+ expressing subsets. We showed for the first time that these two ASDC subsets are present in inflamed human anogenital tissues where HIV transmi
Externí odkaz:
https://doaj.org/article/1e4028ffe06646b1b34da8e1a361e6ce
Autor:
Kevin Danastas, Gerry Guo, Jessica Merjane, Nathan Hong, Ava Larsen, Monica Miranda-Saksena, Anthony L. Cunningham
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Herpes simplex virus-1 (HSV-1) has evolved mechanisms to evade the host immune system and limit the antiviral effects induced by interferon (IFN) produced by local epithelial and immune cells. In this study, we determined the effects of type
Externí odkaz:
https://doaj.org/article/f3457912712941b1824858ab60759adc
Autor:
Wuji Zhang, Brendon Y. Chua, Kevin J. Selva, Lukasz Kedzierski, Thomas M. Ashhurst, Ebene R. Haycroft, Suzanne K. Shoffner-Beck, Luca Hensen, David F. Boyd, Fiona James, Effie Mouhtouris, Jason C. Kwong, Kyra Y. L. Chua, George Drewett, Ana Copaescu, Julie E. Dobson, Louise C. Rowntree, Jennifer R. Habel, Lilith F. Allen, Hui-Fern Koay, Jessica A. Neil, Matthew J. Gartner, Christina Y. Lee, Patiyan Andersson, Sadid F. Khan, Luke Blakeway, Jessica Wisniewski, James H. McMahon, Erica E. Vine, Anthony L. Cunningham, Jennifer Audsley, Irani Thevarajan, Torsten Seemann, Norelle L. Sherry, Fatima Amanat, Florian Krammer, Sarah L. Londrigan, Linda M. Wakim, Nicholas J. C. King, Dale I. Godfrey, Laura K. Mackay, Paul G. Thomas, Suellen Nicholson, Kelly B. Arnold, Amy W. Chung, Natasha E. Holmes, Olivia C. Smibert, Jason A. Trubiano, Claire L. Gordon, Thi H. O. Nguyen, Katherine Kedzierska
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The immune response to SARS-CoV-2 infection is variable but has been linked to prognosis and the development of severe immunopathology. Here the authors assess a range of immune parameters in both peripheral blood and respiratory samples, providing a
Externí odkaz:
https://doaj.org/article/3dbf74c705f948919beba2c6dc7dada4
Autor:
Racha Arnous, Sana Arshad, Kerrie Sandgren, Anthony L. Cunningham, Nicole Carnt, Andrew White
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Mucosal linings of the body, including the conjunctiva, are enriched in tissue-resident memory T cells (TRMs) whose defining feature is their continual tissue protection that does not rely on migration to lymphoid organs to elicit immune res
Externí odkaz:
https://doaj.org/article/97dbdb63436649749abc56ba2e565e74
Autor:
Anouschka Akerman, Vanessa Milogiannakis, Tyra Jean, Camille Esneau, Mariana Ruiz Silva, Timothy Ison, Christina Fichter, Joseph A. Lopez, Deborah Chandra, Zin Naing, Joanna Caguicla, Daiyang Li, Gregory Walker, Supavadee Amatayakul-Chantler, Nathan Roth, Sandro Manni, Thomas Hauser, Thomas Barnes, Anna Condylios, Malinna Yeang, Maureen Wong, Charles S.P. Foster, Kenta Sato, Sharon Lee, Yang Song, Lijun Mao, Allison Sigmund, Amy Phu, Ann Marie Vande More, Stephanie Hunt, Mark Douglas, Ian Caterson, Warwick Britton, Kerrie Sandgren, Rowena Bull, Andrew Lloyd, Jamie Triccas, Stuart Tangye, Nathan W. Bartlett, David Darley, Gail Matthews, Damien J. Stark, Kathy Petoumenos, William D. Rawlinson, Ben Murrell, Fabienne Brilot, Anthony L. Cunningham, Anthony D. Kelleher, Anupriya Aggarwal, Stuart G. Turville
Publikováno v:
EBioMedicine, Vol 90, Iss , Pp 104545- (2023)
Summary: Background: The Omicron era of the COVID-19 pandemic commenced at the beginning of 2022 and whilst it started with primarily BA.1, it was latter dominated by BA.2 and the related sub-lineage BA.5. Following resolution of the global BA.5 wave
Externí odkaz:
https://doaj.org/article/c20ddc7898f64d7197436749654ce9c9
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Herpes simplex viruses (HSV) types 1 and 2 are ubiquitous infections in humans. They cause orofacial and genital herpes with occasional severe complications. HSV2 also predisposes individuals to infection with HIV. There is currently no vaccine or im
Externí odkaz:
https://doaj.org/article/d4c98ddd01204287b233f673d53f53fb
Autor:
Joon Hyung Kim, John Diaz-Decaro, Ning Jiang, Shinn-Jang Hwang, Eun Ju Choo, Maribel Co, Andrew Hastie, David Shu Cheong Hui, Junya Irimajiri, Jacob Lee, Edward Man-Fuk Leung, Haiwen Tang, Tomomi Tsuru, Philip Watson, Zhenhua Wu, Chong-Jen Yu, Yanfei Yuan, Toufik Zahaf, Anthony L. Cunningham, Anne Schuind
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 7, Pp 2050-2057 (2021)
In two large clinical trials (ZOE-50 [NCT01165177] and ZOE-70 [NCT01165229]), two doses of the adjuvanted recombinant zoster vaccine (RZV) demonstrated >90% efficacy (VE) against herpes zoster (HZ) in adults ≥50 years of age (YOA). This post-hoc an
Externí odkaz:
https://doaj.org/article/3f26a5280f08465fa9cb53f30f8d89cb