Výsledky vyhledávání - "Anthony Kales"

Adverse Effects of Modest Sleep Restriction on Sleepiness, Performance, and Inflammatory Cytokines

Autor: Edward O. Bixler, H. Follett, George P. Chrousos, Anthony Kales, Alexandros N. Vgontzas, Hung Mo Lin, E. Zoumakis

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 89:2119-2126

Total sleep restriction in humans is associated with increased daytime sleepiness, decreased performance, and hormonal/metabolic disturbances. The effects of mild chronic sleep restriction that mimic real life are not known. To assess the effects of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7f49f818bbbcf0ac3aae3edeaf93cfb
https://doi.org/10.1210/jc.2003-031562

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Impaired Nighttime Sleep in Healthy OldVersusYoung Adults Is Associated with Elevated Plasma Interleukin-6 and Cortisol Levels: Physiologic and Therapeutic Implications

Autor: Anthony Kales, George P. Chrousos, Alexandros N. Vgontzas, Paolo Prolo, Edward O. Bixler, Hung Mo Lin, Antonio Vela-Bueno, Manolis Zoumakis

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 88:2087-2095

IL-6 and TNF alpha secretion is increased by sleep loss or restriction. IL-6 secretion progressively increases with age, yet its association with decreased quality and quantity of sleep in old adults is unknown. This study examined the alteration of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed562e52a91a34c80050b5e971c1129
https://doi.org/10.1210/jc.2002-021176

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Chronic insomnia is associated with a shift of interleukin-6 and tumor necrosis factor secretion from nighttime to daytime

Autor: Anthony Kales, Paolo Prolo, Dimitris A. Papanicolaou, Alexandros N. Vgontzas, Edward O. Bixler, Hung Mo Lin, George P. Chrousos, Antonio Vela-Bueno, M. Zoumakis

Publikováno v: Metabolism. 51:887-892

Chronic insomnia, by far the most commonly encountered sleep disorder in medical practice, is characterized by difficulty falling or staying asleep at night and increased fatigue during the day. Interleukin-6 (IL-6) and tumor necrosis factor (TNF) ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b88b041722e2c64ad19e985b606396
https://doi.org/10.1053/meta.2002.33357

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Insomnia in Central Pennsylvania

Autor: Edward O. Bixler, Antonio Vela-Bueno, Hung Mo Lin, Anthony Kales, Alexandros N. Vgontzas

Publikováno v: Journal of Psychosomatic Research. 53:589-592

Objective: Establish the association between insomnia and various physical and mental health symptoms as well as objective measures of sleep disturbance while controlling for age, gender and BMI in a large random sample of the general public. Methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940bbe3fa644aa3bb251f35523e7c3cc
https://doi.org/10.1016/s0022-3999(02)00450-6

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Prevalence of Sleep-disordered Breathing in Women

Autor: Anthony Kales, Antonio Vela-Bueno, Alexandros N. Vgontzas, Hung Mo Lin, Thomas R. Ten Have, Jennifer Rein, Edward O. Bixler

Publikováno v: American Journal of Respiratory and Critical Care Medicine. 163:608-613

The prevalence of sleep-disordered breathing has not been well studied in women, especially in terms of the effects of age, body mass index (BMI), and menopause. We evaluated this question using a two-phase random sample from the general population.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628d9fa816d98734231e41c2fcf27a23
https://doi.org/10.1164/ajrccm.163.3.9911064

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Middle-Aged Men Show Higher Sensitivity of Sleep to the Arousing Effects of Corticotropin-Releasing Hormone Than Young Men: Clinical Implications

Autor: Annmarie M. Wittman, Antonio Vela-Bueno, Edward O. Bixler, Hung Mo Lin, Keith Zachman, Anthony Kales, Alexandros N. Vgontzas, George P. Chrousos

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 86:1489-1495

The prevalence of insomnia associated with emotional stress increases markedly in middle-age. Both the top and end hormones of the hypothalamic-pituitary-adrenal axis, i.e. CRH and glucocorticoids, stimulate arousal/wakefulness and inhibit slow wave

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffbcfd1647a1c21f535f6db9e0a3f56c
https://doi.org/10.1210/jcem.86.4.7370

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Polycystic Ovary Syndrome Is Associated with Obstructive Sleep Apnea and Daytime Sleepiness: Role of Insulin Resistance1

Autor: Anthony Kales, Richard S. Legro, Allison Grayev, George P. Chrousos, Edward O. Bixler, Alexandros N. Vgontzas

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 86:517-520

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of premenopausal women, characterized by chronic hyperandrogenism, oligoanovulation, and insulin resistance. Obstructive sleep apnea (OSA) and excessive daytime sleepiness (EDS) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0d9088120d7b5bb59c96112551757239
https://doi.org/10.1210/jcem.86.2.7185

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Differences in Nocturnal and Daytime Sleep Between Primary and Psychiatric Hypersomnia: Diagnostic and Treatment Implications

Autor: C Criley, Anthony Kales, Antonio Vela-Bueno, Edward O. Bixler, Alexandros N. Vgontzas

Publikováno v: Psychosomatic Medicine. 62:220-226

OBJECTIVE The differential diagnosis of primary (idiopathic) vs. psychiatric hypersomnia is challenging because of the lack of specific clinical or laboratory criteria differentiating these two disorders and the frequent comorbidity of mental disorde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492030a189f90a62269c1685fdfea8da
https://doi.org/10.1097/00006842-200003000-00013

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Sleep deprivation effects on the activity of the hypothalamic-pituitary-adrenal and growth axes: potential clinical implications

Autor: George P. Chrousos, Alexandros N. Vgontzas, Philip W. Gold, Edward O. Bixler, George Mastorakos, Anthony Kales

Publikováno v: Clinical Endocrinology. 51:205-215

OBJECTIVES Although several studies have shown that sleep deprivation is associated with increased slow wave sleep during the recovery night, the effects of sleep deprivation on cortisol and growth hormone (GH) secretion the next day and recovery nig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5fb03e42481732702727489a3fc6170
https://doi.org/10.1046/j.1365-2265.1999.00763.x

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Circadian Interleukin-6 Secretion and Quantity and Depth of Sleep

Autor: Angela Lotsikas, Paolo Prolo, Anthony Kales, Dimitris A. Papanicolaou, George P. Chrousos, Edward O. Bixler, Ma-Li Wong, Philip W. Gold, George Mastorakos, Keith Zachman, Ramon C. Hermida, Julio Licinio, Alexandros N. Vgontzas

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 84:2603-2607

Patients with pathologically increased daytime sleepiness and fatigue have elevated levels of circulating interleukin-6 (IL-6). The latter is an inflammatory cytokine, which causes sickness manifestations, including somnolence and fatigue, and activa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeafc122329de00a4ba28d2963dad6ed
https://doi.org/10.1210/jcem.84.8.5894

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