Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anthony K. Mittermaier"'
Autor:
Roberto El-Khoury, Veronica Macaluso, Christopher Hennecker, Anthony K. Mittermaier, Modesto Orozco, Carlos González, Miguel Garavís, Masad J. Damha
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-10 (2023)
The oligonucleotide d(TC5) forms a well-characterized tetrameric i-motif in solution; however, the isolation of dimeric and trimeric intermediates remains challenging. Here, the authors report that 2′-deoxy-2′-fluoroarabinocytidine substitutions
Externí odkaz:
https://doaj.org/article/4633b3ce480d4d24a7df7ba24c55d47e
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Isothermal titration calorimetry (ITC) involves accurately measuring the heat that is released or absorbed in real time when one solution is titrated into another. This technique is usually used to measure the thermodynamics of binding reactions. How
Externí odkaz:
https://doaj.org/article/7dbdc05d098b4d659cf21d1184924699
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Complex assembly pathways often involve transient, partly-formed intermediates that are challenging to characterize. Here, the authors present a simple and rapid spectroscopic thermal hysteresis method for mapping the energy landscapes of supramolecu
Externí odkaz:
https://doaj.org/article/69a96f65f7364d2ebdc35ca9920a4ee7
Autor:
Justin M. Di Trani, Stephane De Cesco, Rebecca O’Leary, Jessica Plescia, Claudia Jorge do Nascimento, Nicolas Moitessier, Anthony K. Mittermaier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
There is growing evidence that the kinetics of interactions between inhibitors and their targets can strongly impact therapeutic efficacy. Here the authors describe an isothermal titration calorimetry-based method that can rapidly quantify inhibition
Externí odkaz:
https://doaj.org/article/695ef23f7e8d4d87a44cc9ad450d7ebc
Publikováno v:
Chemistry – A European Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::500278e20338e17b2b0f63141cb2eef1
https://doi.org/10.1002/chem.202300080
https://doi.org/10.1002/chem.202300080
Autor:
Julia K. Stille, Jevgenijs Tjutrins, Guanyu Wang, Felipe A. Venegas, Christopher Hennecker, Andrés M. Rueda, Itai Sharon, Nicole Blaine, Caitlin E. Miron, Sharon Pinus, Anne Labarre, Jessica Plescia, Mihai Burai Patrascu, Xiaocong Zhang, Alexander S. Wahba, Danielle Vlaho, Mitchell J. Huot, T. Martin Schmeing, Anthony K. Mittermaier, Nicolas Moitessier
Publikováno v:
European Journal of Medicinal Chemistry
Severe diseases such as the ongoing COVID-19 pandemic, as well as the previous SARS and MERS outbreaks, are the result of coronavirus infections and have demonstrated the urgent need for antiviral drugs to combat these deadly viruses. Due to its esse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1caa31a79967b02adbbfb04cbc82d5
http://europepmc.org/articles/PMC8665847
http://europepmc.org/articles/PMC8665847
Autor:
Julia Stille, Jevgenijs Tjutrins, Guanyu Wang, Felipe A. Venegas, Christopher Hennecker, Andres Mauricio Rueda, Itai Sharon, Nicole Blaine, Caitlin E. Miron, Sharon Pinus, Anne Labarre, Jessica Plescia, Mihai Burai Patrascu, Xiaocong Zhang, Alexander S. Wahba, Danielle Vlaho, Mitchell Huot, T. Martin Schmeing, Anthony K Mittermaier, Nicolas Moitessier
Severe diseases such as the ongoing COVID-19 pandemic, as well as the previous SARS and MERS outbreaks, are the result of coronavirus infections and have demonstrated the urgent need for antiviral drugs to combat these deadly viruses. Due to its esse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a36d8047a6c9ad0b9b6ffb8666e7f58
https://doi.org/10.33774/chemrxiv-2021-5twk7-v3
https://doi.org/10.33774/chemrxiv-2021-5twk7-v3
Autor:
Robert W, Harkness, Christopher, Hennecker, J Tassilo, Grün, Anja, Blümler, Alexander, Heckel, Harald, Schwalbe, Anthony K, Mittermaier
Publikováno v:
Nucleic Acids Research
G-quadruplexes (G4s) are four-stranded, guanine-rich nucleic acid structures that can influence a variety of biological processes such as the transcription and translation of genes and DNA replication. In many cases, a single G4-forming nucleic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93e4cad2cbcc91d33e077a113632d0c9
https://pubmed.ncbi.nlm.nih.gov/33469659
https://pubmed.ncbi.nlm.nih.gov/33469659
Autor:
Julia Stille, Jevgenijs Tjutrins, Guanyu Wang, Felipe A. Venegas, Christopher Hennecker, Andres Mauricio Rueda, Caitlin E. Miron, Sharon Pinus, Anne Labarre, Jessica Plescia, Mihai Burai Patrascu, Danielle Vlaho, Mitchell Huot, Anthony K Mittermaier, Nicolas Moitessier
Severe diseases such as the ongoing COVID-19 pandemic, as well as the previous SARS and MERS outbreaks, are the result of coronavirus infections and have demonstrated the urgent need for antiviral drugs to combat these deadly viruses. Due to its esse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b917bcf453eb7c43395b652c44f04f9
https://doi.org/10.26434/chemrxiv.13087742.v1
https://doi.org/10.26434/chemrxiv.13087742.v1