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pro vyhledávání: '"Anthony K. Edmonds"'
Autor:
Andrew McGown, Anthony K. Edmonds, Daniel Guest, Verity L. Holmes, Chris Dadswell, Ramón González-Méndez, Charles A. I. Goodall, Mark C. Bagley, Barnaby W. Greenland, John Spencer
Publikováno v:
Molecules, Vol 27, Iss 16, p 5052 (2022)
A cheap, conventional, sealed heating reactor proved to be a useful alternative to a microwave reactor in the synthesis of a >20-member MIDA boronate library (MIDA = N-methyliminodiacetic acid). Reaction times were 10 min and work-ups were minimal, s
Externí odkaz:
https://doaj.org/article/603bad55e2d14c40b1509e83123af597
Autor:
Anthony K. Edmonds, Catherine S. Oakes, Storm Hassell-Hart, Didier Bruyère, Graham J. Tizzard, Simon J. Coles, Robert Felix, Hannah J. Maple, Graham P. Marsh, John Spencer
Publikováno v:
Organic & Biomolecular Chemistry. 20:4021-4029
ISOX-DUAL is a dual inhibitor of CBP/p300 (IC50 = 0.65 μM) and BRD4 (IC50 = 1.5 μM) bromodomains, and a useful chemical probe for epigenetic research. Aspects of the published synthetic route to this compound and its analogues are small-scale, poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2887fa7399a36e96d3c07b03b74f0a76
https://doi.org/10.1039/d2ob00609j
https://doi.org/10.1039/d2ob00609j