Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Anthony J. Ricci"'
Autor:
Christopher J. Buswinka, David B. Rosenberg, Rubina G. Simikyan, Richard T. Osgood, Katharine Fernandez, Hidetomi Nitta, Yushi Hayashi, Leslie W. Liberman, Emily Nguyen, Erdem Yildiz, Jinkyung Kim, Amandine Jarysta, Justine Renauld, Ella Wesson, Haobing Wang, Punam Thapa, Pierrick Bordiga, Noah McMurtry, Juan Llamas, Siân R. Kitcher, Ana I. López-Porras, Runjia Cui, Ghazaleh Behnammanesh, Jonathan E. Bird, Angela Ballesteros, A. Catalina Vélez-Ortega, Albert S. B. Edge, Michael R. Deans, Ksenia Gnedeva, Brikha R. Shrestha, Uri Manor, Bo Zhao, Anthony J. Ricci, Basile Tarchini, Martín L. Basch, Ruben Stepanyan, Lukas D. Landegger, Mark A. Rutherford, M. Charles Liberman, Bradley J. Walters, Corné J. Kros, Guy P. Richardson, Lisa L. Cunningham, Artur A. Indzhykulian
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-11 (2024)
Abstract Our sense of hearing is mediated by cochlear hair cells, of which there are two types organized in one row of inner hair cells and three rows of outer hair cells. Each cochlea contains 5–15 thousand terminally differentiated hair cells, an
Externí odkaz:
https://doaj.org/article/4c70d4dac13244659ba71b69b8f67db0
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Wang et al. use high-speed imaging to examine the in situ movement of inner hair-cell stereocilia in the mouse ear. They report that these individual cilia move semi-independently within their given bundle, which forms part of a larger complex within
Externí odkaz:
https://doaj.org/article/d16692023cfe401bbdb201df2c95017d
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100637- (2021)
Summary: Fluorescence recovery after photobleaching (FRAP) has been widely used to monitor membrane properties by measuring the lateral diffusion of fluorescent particles. This protocol describes how to perform two-photon FRAP on the stereocilia of l
Externí odkaz:
https://doaj.org/article/b372e7e3dbd54d669ffc3c2fd7418245
Autor:
Anthony W. Peng, Alexandra L. Scharr, Giusy A. Caprara, Dailey Nettles, Charles R. Steele, Anthony J. Ricci
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Hair cell mechanosensitivity resides in the sensory hair bundle, an apical protrusion of actin-filled stereocilia arranged in a staircase pattern. Hair bundle deflection activates mechano-electric transduction (MET) ion channels located near the tops
Externí odkaz:
https://doaj.org/article/e957b52154a5429793b1c52e38e83d51
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101773- (2020)
Summary: The lipid bilayer plays a pivotal role in force transmission to many mechanically-gated channels. We developed the technology to monitor membrane diffusivity in order to test the hypothesis positing that Ca2+ regulates open probability (Po)
Externí odkaz:
https://doaj.org/article/2926d4fde4e84c6388c2c738304fb37d
Autor:
Alfred L. Nuttall, Anthony J. Ricci, George Burwood, James M. Harte, Stefan Stenfelt, Per Cayé-Thomasen, Tianying Ren, Sripriya Ramamoorthy, Yuan Zhang, Teresa Wilson, Thomas Lunner, Brian C. J. Moore, Anders Fridberger
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
The sound envelope is important for speech perception. Here, the authors look at mechanisms by which the sound envelope is encoded, finding that it arises from distortion produced by mechanoelectrical transduction channels. Surprisingly, the envelope
Externí odkaz:
https://doaj.org/article/475cbf140b9d4b45bc152aec6233e3f8
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
The inner ear houses the sensory epithelium responsible for vestibular and auditory function. The sensory epithelia are driven by pressure and vibration of the fluid filled structures in which they are embedded so that understanding the homeostatic m
Externí odkaz:
https://doaj.org/article/0a6df84d9c8c44e890a4b047eefd7d76
Autor:
Clive P. Morgan, Hongyu Zhao, Meredith LeMasurier, Wei Xiong, Bifeng Pan, Piotr Kazmierczak, Matthew R. Avenarius, Michael Bateschell, Ruby Larisch, Anthony J. Ricci, Ulrich Müller, Peter G. Barr-Gillespie
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Hair cells of the inner ear transduce mechanical stimuli like sound or head movements into electrical signals, which are propagated to the central nervous system. The hair-cell mechanotransduction channel remains unidentified. We tested whether three
Externí odkaz:
https://doaj.org/article/d575ed1e6a8c4635817fbfe708a330e9
Autor:
Sandra Meese, Andreia P. Cepeda, Felix Gahlen, Christopher M. Adams, Ralf Ficner, Anthony J. Ricci, Stefan Heller, Ellen Reisinger, Meike Herget
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 9 (2017)
Otoferlin is essential for fast Ca2+-triggered transmitter release from auditory inner hair cells (IHCs), playing key roles in synaptic vesicle release, replenishment and retrieval. Dysfunction of otoferlin results in profound prelingual deafness. De
Externí odkaz:
https://doaj.org/article/24114096d00b4d8cb595cc8804cae68c
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Aminoglycosides are potent antibiotics deployed worldwide despite their known side-effect of sensorineural hearing loss. The main etiology of this sensory deficit is death of inner ear sensory hair cells selectively triggered by aminoglycosides. For
Externí odkaz:
https://doaj.org/article/85e5ea0a937c44898a54cae239fc7f15