Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Anthony J. R. Hickey"'
Autor:
Lyvia R. Bowering, Tristan J. McArley, Jules B. L. Devaux, Anthony J. R. Hickey, Neill A. Herbert
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Marine organisms are under threat from a simultaneous combination of climate change stressors, including warming sea surface temperatures (SST), marine heatwave (MHW) episodes, and hypoxic events. This study sought to investigate the impacts of these
Externí odkaz:
https://doaj.org/article/db64a9e2ccf3439dbbcacb39f89ca84a
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Temperature is a key factor that affects all levels of organization. Minute shifts away from thermal optima result in detrimental effects that impact growth, reproduction and survival. Metabolic rates of ectotherms are especially sensitive t
Externí odkaz:
https://doaj.org/article/5e37441785ec4cc7af6aba19227ba2ad
Autor:
Hsiang-Wei Wang, Cameron Bringans, Anthony J. R. Hickey, John A. Windsor, Paul A. Kilmartin, Anthony R. J. Phillips
Publikováno v:
Signals, Vol 2, Iss 1, Pp 138-158 (2021)
Oxidative stress plays a pivotal role in the pathogenesis of many diseases, but there is no accurate measurement of oxidative stress or antioxidants that has utility in the clinical setting. Cyclic Voltammetry is an electrochemical technique that has
Externí odkaz:
https://doaj.org/article/ff27a1daaa934a44953be7b6a45966af
Autor:
Johanes K. Kasim, Jiwon Hong, Anthony J. R. Hickey, Anthony R. J. Phillips, John A. Windsor, Paul W. R. Harris, Margaret A. Brimble, Iman Kavianinia
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 287 (2023)
Pancreatic ductal adenocarcinoma remains a highly debilitating condition with no effective disease-modifying interventions. In our search for natural products with promising anticancer activity, we identified the aminolipopeptide trichoderin A as a p
Externí odkaz:
https://doaj.org/article/4a4bf5fdacd7466e878c6d5f128b7748
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231091 (2020)
Acute heat shock has previously been shown to improve subsequent low O2 (hypoxia) tolerance in an intertidal fish species, a process known as cross-tolerance, but it is not known whether this is a widespread phenomenon. This study examined whether a
Externí odkaz:
https://doaj.org/article/dce880d73c3347398d6c8b2bc68cd849
Autor:
Chantal A. Pileggi, Christopher P. Hedges, Randall F. D’Souza, Brenan R. Durainayagam, Nina Zeng, Vandre C. Figueiredo, Anthony J. R. Hickey, Cameron J. Mitchell, David Cameron-Smith
Publikováno v:
European Journal of Applied Physiology. 123:249-260
Autor:
Jules B. L. Devaux, Christopher P. Hedges, Nigel Birch, Neill Herbert, Gillian M. C. Renshaw, Anthony J. R. Hickey
Publikováno v:
Frontiers in Physiology, Vol 9 (2019)
The vertebrate brain is generally very sensitive to acidosis, so a hypoxia-induced decrease in pH is likely to have an effect on brain mitochondria (mt). Mitochondrial respiration (JO2) is required to generate an electrical gradient (ΔΨm) and a pH
Externí odkaz:
https://doaj.org/article/bcf0e336f7a6442691a0eafd0a400902
Autor:
Jules B. L. Devaux, Chris P. Hedges, Nigel Birch, Neill Herbert, Gillian M. C. Renshaw, Anthony J. R. Hickey
Publikováno v:
Journal of Comparative Physiology B.
While oxygen is essential for oxidative phosphorylation, O2 can form reactive species (ROS) when interacting with electrons of mitochondrial electron transport system. ROS is dependent on O2 pressure (PO2) and has traditionally been assessed in O2 sa
Autor:
Shouryadipta Ghosh, Kenneth Tran, Lea M D Delbridge, Anthony J R Hickey, Eric Hanssen, Edmund J Crampin, Vijay Rajagopal
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 12, p e1006640 (2018)
Recent electron microscopy data have revealed that cardiac mitochondria are not arranged in crystalline columns but are organised with several mitochondria aggregated into columns of varying sizes spanning the cell cross-section. This raises the ques
Externí odkaz:
https://doaj.org/article/685ae461511743d199a4935553e960f2
Publikováno v:
Functional Ecology. 35:2282-2293