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pro vyhledávání: '"Anthony J. Pacitti"'
Autor:
Anthony J. Pacitti, Wiley W. Souba
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 16:569-578
The bloodstream provides a readily available pool of amino acids, which can be taken up by all cells of the body to support the myriad of biochemical reactions that are essential for life. The transport of amino acids into the cytoplasm occurs via fu
Publikováno v:
Annals of Surgery. 216:353-362
Human growth hormone (GH) has been shown to improve nitrogen balance in surgical patients and to decrease urea production. This has been thought to be due primarily to an increase in protein synthesis in skeletal muscle. Little attention has focused
Publikováno v:
Journal of Surgical Research. 51:46-53
The mechanisms by which hepatic alanine consumption is increased during endotoxemia were investigated to gain further insight into the altered amino acid metabolism which characterizes critical illness. Rats were studied 12 hr after receiving endotox
Autor:
Mohan K. Raizada, Jaime F. Puig, Fulton T. Crews, Nicholas J. Guzman, Colin Sumners, Anthony J. Pacitti
Publikováno v:
Brain Research. 527:318-325
Binding of [125I]HEAT to membranes prepared from primary cultures of astrocytic glial cells was time-dependent and 70-85% specific. Various adrenergic agonists and antagonists competed for [125I]HEAT binding according to the potencies of prazosin gre
Publikováno v:
JPEN. Journal of parenteral and enteral nutrition. 19(1)
Endotoxemia is characterized by a marked increase in the uptake of amino acids by the liver, but the regulation of this response has not been fully elucidated. In the current study, we investigated the potential role of prostaglandins as mediators of
Publikováno v:
The Journal of surgical research. 54(5)
Glutamine uptake by the liver is accelerated during endotoxemia, but little is known regarding the influence of sepsis on the plasma membrane transport systems catalyzing hepatic glutamine uptake. We hypothesized that this augmented uptake was due to
Publikováno v:
The Journal of surgical research. 53(3)
The mechanisms underlying the accelerated hepatic consumption of glutamine that occurs during endotoxemia were investigated in rats 12 hr after treatment with Escherichia coli lipopolysaccharide. Hepatic glutamine delivery and consumption were calcul
Publikováno v:
Surgical oncology. 1(2)
The mechanisms potentially controlling the net release of glutamine by the liver that occurs in tumour-bearing rats were investigated. Studies were undertaken when the tumour comprised approximately 7% (15 +/- 2 g) of total body weight. Hepatic gluta
Publikováno v:
Journal of neurochemistry. 47(4)
Neuronal cells in primary culture from 1-day-old brains of normotensive, Wistar-Kyoto strain (WKY) and spontaneously hypertensive (SH) rats have been utilized to study the expression of α1-adrenergic receptors. Binding of a selective α1 antagonist,