Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Anthony J. Kim"'
Autor:
Nina P. Connolly, Amol C. Shetty, Jesse A. Stokum, Ina Hoeschele, Marni B. Siegel, C. Ryan Miller, Anthony J. Kim, Cheng-Ying Ho, Eduardo Davila, J. Marc Simard, Scott E. Devine, John H. Rossmeisl, Eric C. Holland, Jeffrey A. Winkles, Graeme F. Woodworth
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract Glioma is a unique neoplastic disease that develops exclusively in the central nervous system (CNS) and rarely metastasizes to other tissues. This feature strongly implicates the tumor-host CNS microenvironment in gliomagenesis and tumor pro
Externí odkaz:
https://doaj.org/article/f2d89c7796d7442691323a555b449266
Autor:
Sunipa Majumdar, Aniket S. Wadajkar, Hanan Aljohani, Mark A. Reynolds, Anthony J. Kim, Meenakshi Chellaiah
Publikováno v:
International Journal of Cell Biology, Vol 2019 (2019)
We have recently demonstrated that a small molecular weight amino-terminal peptide of L-plastin (10 amino acids; “MARGSVSDEE”) suppressed the phosphorylation of endogenous L-plastin. Therefore, the formation of nascent sealing zones (NSZs) and bo
Externí odkaz:
https://doaj.org/article/3c50101b68414a9d82d173968ead2803
Autor:
Bryan G. Harder, Mylan R. Blomquist, Junwen Wang, Anthony J. Kim, Graeme F. Woodworth, Jeffrey A. Winkles, Joseph C. Loftus, Nhan L. Tran
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Glioblastoma (GBM) is one of the most common, deadly, and difficult-to-treat adult brain tumors. Surgical removal of the tumor, followed by radiotherapy (RT) and temozolomide (TMZ) administration, is the current treatment modality, but this regimen o
Externí odkaz:
https://doaj.org/article/0c2fd300726c436ebd4d086c12e334b5
Autor:
Nikhil Pandey, Valentina Simon, Marina Mazur, Gijung Kwak, Richard C. Boucher, Siddharth Kaup Shenoy, Eric Han, Namho Kim, Susan E Birket, Jason Rodriguez, Jung Soo Suk, Steven M. Rowe, Justin Hanes, Anthony J. Kim, Xinyuan Zuo, Alessandra Livraghi-Butrico
Publikováno v:
Thorax
IntroductionInhaled gene therapy of muco-obstructive lung diseases requires a strategy to achieve therapeutically relevant gene transfer to airway epithelium covered by particularly dehydrated and condensed mucus gel layer. Here, we introduce a synth
Autor:
Christine P. Carney, Anshika Kapur, Pavlos Anastasiadis, Rodney M. Ritzel, Chixiang Chen, Graeme F. Woodworth, Jeffrey A. Winkles, Anthony J. Kim
Publikováno v:
Molecular pharmaceutics.
Triple-negative breast cancer (TNBC) patients with brain metastasis (BM) face dismal prognosis due to the limited therapeutic efficacy of the currently available treatment options. We previously demonstrated that paclitaxel-loaded PLGA-PEG nanopartic
Autor:
Sumiao Pang, Anshika Kapur, Keri Zhou, Pavlos Anastasiadis, Nicholas Ballirano, Anthony J. Kim, Jeffrey A. Winkles, Graeme F. Woodworth, Huang‐Chiao Huang
Publikováno v:
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. 14(5)
Laser interstitial thermal therapy (LITT) guided by magnetic resonance imaging (MRI) is a new treatment option for patients with brain and non-central nervous system (non-CNS) tumors. MRI guidance allows for precise placement of optical fiber in the
Autor:
Jeffrey A. Winkles, Anthony J. Kim, Nikhil Pandey, Anshika Kapur, Graeme F. Woodworth, Christine P. Carney, Aniket S. Wadajkar, Jimena G. Dancy
Publikováno v:
Cancer Research. 81:PS18-24
Despite dramatic improvements in the treatment of primary breast cancers, there currently are no effective targeted therapeutics for women diagnosed with metastatic triple negative breast cancer (mTNBC), resulting in an overall survival of just ~13 m
Publikováno v:
Advanced Drug Delivery Reviews. 189:114522
Autor:
Nikhil, Pandey, Pavlos, Anastasiadis, Christine P, Carney, Pranjali P, Kanvinde, Graeme F, Woodworth, Jeffrey A, Winkles, Anthony J, Kim
Publikováno v:
Advanced Drug Delivery Reviews. 188:114415
Glioblastoma (GBM) is the most common malignant adult brain cancer with no curative treatment strategy. A significant hurdle in GBM treatment is effective therapeutic delivery to the brain-invading tumor cells that remain following surgery within fun
Autor:
Graeme F. Woodworth, Nikhil Pandey, Anthony J. Kim, Jeffrey A. Winkles, Christine P. Carney, Anshika Kapur
Publikováno v:
Drug Delivery and Translational Research
Brain metastases (BMs) are the most common type of brain tumor, and the incidence among breast cancer (BC) patients has been steadily increasing over the past two decades. Indeed, ~ 30% of all patients with metastatic BC will develop BMs, and due to