MT1 and MT2 Melatonin Receptors: A Therapeutic Perspective

Autor: Jiabei Liu, Margarita L. Dubocovich, Marina Popovska-Gorevski, Ekue B. Adamah-Biassi, Shannon J. Clough, Anthony J. Hutchinson

Publikováno v: Annual Review of Pharmacology and Toxicology. 56:361-383

Melatonin, or 5-methoxy-N-acetyltryptamine, is synthesized and released by the pineal gland and locally in the retina following a circadian rhythm, with low levels during the day and elevated levels at night. Melatonin activates two high-affinity G p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a83c10f3879b3f317a7b85d2b733e4
https://doi.org/10.1146/annurev-pharmtox-010814-124742

List of Contributors

Autor: Renata Rigacci Abdalla, Tomohiro Abekawa, Przemysław Adamczyk, Wendy Adams, Peter H. Addy, Yukio Ago, María Álvaro-Bartolomé, Martina Andellini, Matthew E. Andrzejewski, Gustavo A. Angarita, Mariana Angoa-Pérez, John H. Anneken, Luís Antunes, Yalda Hosseinzadeh Ardakani, Mustafa Aydin, Nima Badri, Ram C. Bajpai, Daniel José Barbosa, Alfonso Barrós-Loscertales, Debasish Basu, Benjamin Becker, Jacob T. Beckley, Pablo García Bermejo, Laís F. Berro, Amanda L. Blaker, Ede Bodoki, Krzysztof Borowiak, Scott E. Bowen, Patricia A. Broderick, Berit Brogaard, Giovana Brolese, T.M. Brunt, T. Buchborn, Eduardo R. Butelman, Raul Caetano, Sónia Campos, Sofija V. Canavan, João Paulo Capela, Manolo Carta, Félix Carvalho, Lucia Carvelli, Briony J. Catlow, Young-Tae Chang, Himanshu K. Chaturvedi, Lela Chilachava, Aree Choodum, Shannon J. Clough, Vanessa Coelho-Santos, Ana Maria Coimbra, Stuart A. Collins, Bru Cormand, Albert Dahan, Elias Dakwar, Antonio Dávalos E., Cor de Jong, Maria de Lourdes Bastos, Marc R. Del Bigio, Teresa Dembińska, Ugur Deveci, D.C. Dieterich, Boukje Dijkstra, Dean E. Dluzen, Margarita L. Dubocovich, Carlos García Esperón, Chun-Kai Fang, Vahid Farnia, Luís Félix, Noelia Fernàndez-Castillo, Daniel Flack, Elisabeth Frauger, Joel Frohlich, Daniela F. Fukushiro, Daniel A. García, M. Julia García-Fuster, Jesús A. García-Sevilla, Eric L. Garland, Dimitria Electra Gatzia, Lia Gelazonia, Abhishek Ghosh, Roy Gigengack, Senobar Golshani, Joana Gonçalves, Javier González-Maeso, Ingmar Gorman, David K. Grandy, G. Grecksch, Alissa M. Greer, Gary A. Gudelsky, Casey Guillot, Joshua M. Gulley, Yoko Hagino, Robert M. Hallock, Emily R. Hankosky, James B. Hanks, Carl Hart, H.W.W. Hasselmann, Hirotake Hida, Sarah E. Hodges, Nicole Holder, André W. Hollais, V. Höllt, Jiri Horacek, Matthew O. Howard, Fleur Margaret Howells, Skye Hsin-Hsien Yeh, Mei Huang, Anthony J. Hutchinson, Jeng-Jong Hwang, Kazutaka Ikeda, Jennifer E. Iudicello, Ahmad Jalloh, Bardia Jamali, Nadezhda Japaridze, Eiichi Jodo, Chantele Joordens, Rasmon Kalayasiri, Rama Kamal, Etsuko Kamegaya, Tadahiro Katayama, Adam W. Keasling, Ruri Kikura-Hanajiri, Matthew Kirkpatrick, Béla Kiss, Rita Kočárová, Saurabh S. Kokane, Mary Jeanne Kreek, Peter R. Kufahl, Donald M. Kuhn, Takeshi Kumazawa, Snezana Kusljic, Krzysztof Łabuz, Maryse Lapeyre-Mestre, Ronaldo Ramos Laranjeira, Andrew J. Lawrence, Byung Dae Lee, Ricardo Alexandre Leitão, L. Stan Leung, Chiang-Shan R. Li, Meng Li, Qing Lin, Felicia Loghin, Elena López-Cancio M., Jennifer Lyke, Michael Lyvers, Scott Macdonald, Clarice Sandi Madruga, Michael Maes, Timothy J. Maher, Jingyi Ma, Chitra D. Mandyam, Claudia Mardones, Gina Martin, Luciana Massaro, Toshio Matsuda, M.T.B. McMaster, Richard H. Melloni, Herbert Y. Meltzer, Joëlle Micallef, Maria Mironidou-Tzouveleki, Masayoshi Mishina, Sandro Mitsuhiro, Christian Montag, Elisabeth Moore, Erin E. Morgan, Peter T. Morgan, Satoshi Morimoto, Thomas R. Morrison, Anna Moszczynska, Akihiro Mouri, Antonio Napolitano, Nichole M. Neugebauer, Niamh NicDaeid, Charles D. Nichols, Martin Nizama-Valladolid, Yukihiro Noda, Nicole A. Northrop, M. Foster Olive, Rory D. Ostrow, Linda C.J. Oudejans, Tomas Palenicek, Arvind Pandey, Mariusz Papp, Ioannis D. Passos, Madan Kumar Paudel, Maria A. Perillo, Christina J. Perry, Nataša Petronijević, Siripan Phattanarudee, Ilana Pinsky, Nino Pochkhidze, Anca Pop, Marianne Possa, Barbara Potocka-Banaś, Boris B. Quednow, Nevena V. Radonjić, Lakshmi Rajagopal, Marta Ribasés, Lesley A. Ricci, Carola Vergara Rosales, Mohammad-Reza Rouini, Juan Sanchez-Ramos, Renan Santos-Baldaia, Siddharth Sarkar, Kaori Sasaki-Tabata, Naomi Sato, Tomonori Sato, Wakako Sawada, Silvia Bassani Schuch, Setsuko Sekita, Eduardo Alvear Serrano, Behjat Sheikholeslami, Osamu Shirota, Ana Paula Silva, Nicola Simola, Derek P. Simon, Ichiro Sora, Anne Orgler Sordi, Mitchell G. Spring, Katarzyna Stebelska, Haruhiko Sugimura, Yoshiaki Suzuki, Kazuhiro Takuma, Hiroyuki Tanaka, Meshkat Torkamanian, Pasarapa Towiwat, Anahí V. Turina, Filip Tyls, J.G.C. van Amsterdam, W. van den Brink, Maarten van den Buuse, John Darrell Van Horn, Martijn van Noorden, Monique van Velzen, Carlos Venâncio, Dietrich von Baer, Lisia von Diemen, Martin Walter, Fang Wang, Erica Weber, Petr Winkler, Steven Paul Woods, John J. Woodward, Chun-Fu Wu, Raphael Wuo-Silva, Wang Xu, Bryan K. Yamamoto, Hideko Yamamoto, Toshifumi Yamamoto, Jing-Yu Yang, Duanting Zhai, Mzia Zhvania, Jordan K. Zjawiony

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ec7ea3eba339fb059bdd8a8e402a84b
https://doi.org/10.1016/b978-0-12-800212-4.01002-5

Genetic deletion of MT1and MT2melatonin receptors differentially abrogates the development and expression of methamphetamine-induced locomotor sensitization during the day and the night in C3H/HeN mice

Autor: Randall L. Hudson, Margarita L. Dubocovich, Anthony J. Hutchinson

Publikováno v: Journal of Pineal Research. 53:399-409

This study explored the role of the melatonin receptors in methamphetamine (METH)-induced locomotor sensitization during the light and dark phases in C3H/HeN mice with genetic deletion of theMT1 and/or MT2 melatonin receptors. Six daily treatments wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1255c176c8f5903a123de8d490c4c2fe
https://doi.org/10.1111/j.1600-079x.2012.01010.x

Induction of angiogenic immediate early genes by activation of FP prostanoid receptors in cultured human ciliary smooth muscle cells

Autor: Anthony J. Hutchinson, John W. Regan, Wei Xu, Chih Ling Chou, David F. Woodward, S. C. Coons, W. Daniel Stamer

Publikováno v: Current eye research. 35(5)

Agonists of the F prostanoid receptor for prostaglandin F2alpha exert. exert an ocular hypotensive effect that has been attributed to increased aqueous humor outflow through the uveoscleral pathway. Although tissue remodeling of the ciliary muscle ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd389c69e7144d8bedb384062b30139
https://pubmed.ncbi.nlm.nih.gov/20450254

PGF2α Stimulates FP Prostanoid Receptor Mediated Crosstalk Between Ras/Raf Signaling and Tcf Transcriptional Activation

Autor: Anthony J. Hutchinson, Davelene D. Israel, Wei Xu, Chih Ling Chou, John W. Regan

Prostaglandin-F(2alpha) (PGF(2alpha)) is a product of the cyclooxygenase pathway and is a local signaling molecule that activates a G-protein coupled prostanoid receptor named FP. FP receptors can stimulate T-cell factor (Tcf) transcriptional activat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb6510c4d6d6b983a68eefa349bc8ff
https://europepmc.org/articles/PMC2734959/